Restoring function in exhausted CD8 T cells during chronic viral infection (Q28289222)

object named as

Gordon J Freeman

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Arlene Sharpe

object named as

Arlene H Sharpe

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E. John Wherry

object named as

E John Wherry

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author name string

Daniel L Barber

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David Masopust

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Baogong Zhu

T cells and viral persistence: lessons from diverse infections

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language of work or name

English

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publication date

9 February 2006

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published in

Nature

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volume

439

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issue

7077

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page(s)

682-7

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cites work

1 reference

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Antigen-independent memory CD8 T cells do not develop during chronic viral infection

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

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Viral immune evasion due to persistence of activated T cells without effector function

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Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

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Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know

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Immunopathogenesis and immunotherapy in AIDS virus infections

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Immunology of hepatitis B virus and hepatitis C virus infection

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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The B7-CD28 superfamily

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Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

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B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

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Helping the CD8(+) T-cell response

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In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses

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CTLA-4: new insights into its biological function and use in tumor immunotherapy

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Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

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Modifications of CD8+ T cell function during in vivo memory or tolerance induction

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The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4+ T Cells

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PD-1 inhibits antiviral immunity at the effector phase in the liver

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Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

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Adoptive-cell-transfer therapy for the treatment of patients with cancer

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Therapeutic vaccines for chronic infections

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Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination

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Molecular and functional profiling of memory CD8 T cell differentiation.

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Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

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7 January 2021

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

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7 January 2021

Paradoxical role of programmed death-1 ligand 2 in Th2 immune responses in vitro and in a mouse asthma model in vivo

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Endothelial expression of PD‐L1 and PD‐L2 down‐regulates CD8+ T cell activation and cytolysis

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7 January 2021

Identifiers

DOI

10.1038/NATURE04444

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1018989545

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Fatcat ID

release_py2orypubnbszccjrgguy5loum

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16382236

1 reference

Consolidated OpenCitations Corpus – April 2017