Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1) (Q28280453)

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English	Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)	scientific article

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7 January 2020

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1) (English)

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7 January 2020

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placebo-controlled trial

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monoclonal antibody

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Alexandra Boer Kimball

2

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7 January 2020

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Kim A Papp

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Craig L Leonardi

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7 January 2020

Newman Yeilding

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7 January 2020

Cynthia Guzzo

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7 January 2020

Yuhua Wang

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7 January 2020

Shu Li

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7 January 2020

Lisa T Dooley

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7 January 2020

Kenneth B Gordon

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7 January 2020

PHOENIX 1 study investigators

10

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7 January 2020

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1 May 2008

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7 January 2020

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7 January 2020

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7 January 2020

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7 January 2020

1665-1674

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7 January 2020

1 reference

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What have we learned in dermatology from the biologic therapies?

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Biological therapies in the systemic management of psoriasis: International Consensus Conference

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2960725-4

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

1 reference

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Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

1 reference

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In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

1 reference

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Interleukin-12, interleukin-23, and psoriasis: current prospects

1 reference

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A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

1 reference

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Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial

1 reference

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

1 reference

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Sequential Treatment Assignment with Balancing for Prognostic Factors in the Controlled Clinical Trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2808%2960725-4

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Severe Psoriasis – Oral Therapy with a New Retinoid

1 reference

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Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use.

1 reference

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Validation of immunoassays used to assess immunogenicity to therapeutic monoclonal antibodies

1 reference

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Definitions of Measures of Effect Duration for Psoriasis Treatments

1 reference

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IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice

1 reference

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

1 reference

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The immunologic basis for the treatment of psoriasis with new biologic agents

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A proinflammatory activity of interleukin 8 in human skin: expression of the inducible nitric oxide synthase in psoriatic lesions and cultured keratinocytes

1 reference

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Cracking the cytokine code in psoriasis

1 reference

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7 January 2021

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IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human.

1 reference

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

1 reference

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The IL-12 family member p40 chain as a master switch and novel therapeutic target in psoriasis

1 reference

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A 50% reduction in the Psoriasis Area and Severity Index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis.

1 reference

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Risk of Myocardial Infarction in Patients With Psoriasis

1 reference

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1 reference

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The role of interleukin-12 in human infectious diseases: only a faint signature

1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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1 reference

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Adherence to treatment in patients with psoriasis.

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10.1016/S0140-6736(08)60725-4

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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7 January 2020

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1 reference

Consolidated OpenCitations Corpus – April 2017

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2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18486739%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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