Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers (Q28275567)

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7 January 2021

Inactive type II and type I receptors for TGF beta are dominant inhibitors of TGF beta-dependent transcription

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7 January 2021

Receptors for the TGF-beta ligand family

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7 January 2021

Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA

1 reference

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7 January 2021

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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7 January 2021

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

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7 January 2021

Betaglycan presents ligand to the TGF beta signaling receptor.

1 reference

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7 January 2021

Function of the Type V Transforming Growth Factor β Receptor in Transforming Growth Factor β-induced Growth Inhibition of Mink Lung Epithelial Cells

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7 January 2021

Mechanism of activation of the TGF-beta receptor

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7 January 2021

Positive and negative regulation of type II TGF-beta receptor signal transduction by autophosphorylation on multiple serine residues

1 reference

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7 January 2021

The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues

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7 January 2021

Determination of type I receptor specificity by the type II receptors for TGF-beta or activin

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7 January 2021

Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases

1 reference

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7 January 2021

The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands

1 reference

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7 January 2021

A transforming growth factor beta type I receptor that signals to activate gene expression

1 reference

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7 January 2021

Transforming Growth Factor (TGF-β)-specific Signaling by Chimeric TGF-β Type II Receptor with Intracellular Domain of Activin Type IIB Receptor

1 reference

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7 January 2021

A kinase subdomain of transforming growth factor-β (TGF-β) type I receptor determines the TGF-β intracellular signaling specificity

1 reference

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7 January 2021

Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.

1 reference

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7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970299-4

7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

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7 January 2021

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1 reference

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7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

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7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

1 reference

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7 January 2021

Smad6 inhibits signalling by the TGF-beta superfamily

1 reference

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7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

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7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970299-4

7 January 2021

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

1 reference

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7 January 2021

Characterization of functional domains within Smad4/DPC4

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970299-4

7 January 2021

DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970299-4

7 January 2021

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 reference

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7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

1 reference

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7 January 2021

1 reference

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7 January 2021

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

1 reference

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7 January 2021

Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

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7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

1 reference

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7 January 2021

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

1 reference

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7 January 2021

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

1 reference

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7 January 2021

The types II and III transforming growth factor-beta receptors form homo-oligomers

1 reference

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7 January 2021

Ligand-induced dimerization of the extracellular domain of the TGF-beta receptor type II.

1 reference

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7 January 2021

Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.

1 reference

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7 January 2021

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

1 reference

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7 January 2021

Controlling Signal Transduction with Synthetic Ligands

1 reference

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7 January 2021

TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins

1 reference

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7 January 2021

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

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7 January 2021

Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen

1 reference

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7 January 2021

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970299-4

7 January 2021

Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization

1 reference

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7 January 2021

Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins

1 reference

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7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

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7 January 2021

Phosphorylation-dependent interaction of the cytoplasmic domains of the type I and type II transforming growth factor-beta receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970299-4

7 January 2021

Ligand-independent activation of transforming growth factor (TGF) beta signaling pathways by heteromeric cytoplasmic domains of TGF-beta receptors

1 reference

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7 January 2021

Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment

1 reference

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7 January 2021

Biosynthesis of the type I and type II TGF-beta receptors. Implications for complex formation

1 reference

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7 January 2021

Processing of the transforming growth factor beta type I and II receptors. Biosynthesis and ligand-induced regulation

1 reference

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7 January 2021

Chimeric granulocyte/macrophage colony-stimulating factor/transforming growth factor-beta (TGF-beta) receptors define a model system for investigating the role of homomeric and heteromeric receptors in TGF-beta signaling

1 reference

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7 January 2021

Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes.

1 reference

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7 January 2021

Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta

1 reference

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7 January 2021

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

1 reference

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7 January 2021

Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization

1 reference

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7 January 2021