Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases (Q28240495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9182527%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases (English)

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Neural precursor cell expressed, developmentally down-regulated 4

3 November 2019

main subject

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Ubiquitin protein ligase E3A

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Ubiquitin-conjugating enzyme E2D 2A

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Zeta-chain (TCR) associated protein kinase

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author

Shigetsugu Hatakeyama

series ordinal

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3 November 2019

J P Jensen

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3 November 2019

A M Weissman

series ordinal

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3 November 2019

language of work or name

English

0 references

publication date

1 June 1997

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Journal of Biological Chemistry

3 November 2019

published in

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3 November 2019

volume

272

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3 November 2019

issue

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3 November 2019

page(s)

15085-15092

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3 November 2019

1 reference

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The ubiquitin-proteasome proteolytic pathway

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Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

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Roles of ubiquitinylation in proteolysis and cellular regulation

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Structure and functions of the 20S and 26S proteasomes

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Ubiquitin-dependent protein degradation

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Regulating protein degradation by ubiquitination

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Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

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Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

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A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

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The ubiquitin-conjugation system

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The ubiquitin system for protein degradation

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

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The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

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A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

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Degradation of the proto-oncogene product c-Fos by the ubiquitin proteolytic system in vivo and in vitro: identification and characterization of the conjugating enzymes

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Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

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Degradation of G alpha by the N-end rule pathway

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Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

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Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

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Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

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Identification of a set of genes with developmentally down-regulated expression in the mouse brain

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Characterization of a novel protein-binding module--the WW domain

21 January 2018

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The rsp5-domain is shared by proteins of diverse functions

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Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

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Identification of a family of closely related human ubiquitin conjugating enzymes

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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

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T cell antigen receptor ubiquitination is a consequence of receptor-mediated tyrosine kinase activation

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Association of human papillomavirus types 16 and 18 E6 proteins with p53.

21 January 2018

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Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent

21 January 2018

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The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

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The ubc-2 gene of Caenorhabditis elegans encodes a ubiquitin-conjugating enzyme involved in selective protein degradation

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53

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ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

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E6-AP directs the HPV E6-dependent inactivation of p53 and is representative of a family of structurally and functionally related proteins.

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The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme

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Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor

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Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes

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NF-kappa B: a lesson in family values

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Isolation, characterization, and partial purification of a novel ubiquitin-protein ligase, E3. Targeting of protein substrates via multiple and distinct recognition signals and conjugating enzymes

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The transmembrane domain of a carboxyl-terminal anchored protein determines localization to the endoplasmic reticulum

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The yeast UBC4 ubiquitin conjugating enzyme monoubiquitinates itself in vivo: evidence for an E2-E2 homointeraction

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Identifiers

DOI

10.1074/JBC.272.24.15085

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9182527%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9182527%20AND%20SRC:MED&resulttype=core&format=json