The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways (Q28236956)

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scientific article (publication date: 21 July 2006)

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English	The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways	scientific article (publication date: 21 July 2006)

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20 January 2020

The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways (English)

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20 January 2020

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Gwénola Boulday

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16644735%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Thibaut Quillard

4

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20 January 2020

Beatrice Charreau

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20 January 2020

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Juliette Fitau

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20 January 2020

Flora Coulon

3

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20 January 2020

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27 April 2006

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20 January 2020

Journal of Biological Chemistry

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20 January 2020

281

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20 January 2020

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20 January 2020

20148-20159

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20 January 2020

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Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Characterization of Lnk. An adaptor protein expressed in lymphocytes

1 reference

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Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

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Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice

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Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins

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Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk

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Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein

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A simplified system for generating recombinant adenoviruses

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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21 January 2018

Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

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Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways

1 reference

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NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation

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A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

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21 January 2018

Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways

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Role of Akt signaling in vascular homeostasis and angiogenesis

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Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types.

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Protein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo

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Modulation of endothelial cell apoptosis by heme oxygenase-1-derived carbon monoxide

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Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation

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Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

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21 January 2018

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

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21 January 2018

CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action

1 reference

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21 January 2018

Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alpha

1 reference

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21 January 2018

Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

1 reference

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21 January 2018

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10.1074/JBC.M510997200

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16644735%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16644735%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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