Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2)

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Unique expression of major histocompatibility complex class I proteins in the absence of glucose trimming and calnexin association

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The N-terminal region of tapasin is required to stabilize the MHC class I loading complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The quantity of naturally processed peptides stably bound by HLA-A*0201 is significantly reduced in the absence of tapasin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Increased efficiency of folding and peptide loading of mutant MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Elucidation of the genetic basis of the antigen presentation defects in the mutant cell line .220 reveals polymorphism and alternative splicing of the tapasin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Calcium, a signaling molecule in the endoplasmic reticulum?

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Ca2+ regulation of interactions between endoplasmic reticulum chaperones.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The nature of the MHC class I peptide loading complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Rat tapasin: cDNA cloning and identification as a component of the class I MHC assembly complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Disulfide bond isomerization and the assembly of MHC class I-peptide complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

A role for calnexin in the assembly of the MHC class I loading complex in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

ER quality control: towards an understanding at the molecular level

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

How does TAP associate with MHC class I molecules?

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The role of ERp57 in disulfide bond formation during the assembly of major histocompatibility complex class I in a synchronized semipermeabilized cell translation system

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Identification of the Tapasin gene in the chicken major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Dependence of peptide binding by MHC class I molecules on their interaction with TAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Regulation of MHC class I heterodimer stability and interaction with TAP by tapasin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Sequence, linkage to H2-K, and function of mouse tapasin in MHC class I assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Interactions of HLA-B27 with the peptide loading complex as revealed by heavy chain mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Association of ERp57 with mouse MHC class I molecules is tapasin dependent and mimics that of calreticulin and not calnexin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Regulation of MHC class I transport by the molecular chaperone, calnexin (p88, IP90).

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The major and a minor class II beta-chain (B-LB ) gene flank the Tapasin gene in the B-F /B-L region of the chicken major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Dependence of elevated human leukocyte antigen class I molecule expression on increased heavy chain, light chain (beta 2-microglobulin), transporter associated with antigen processing, tapasin, and peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Translocation of long peptides by transporters associated with antigen processing (TAP).

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Physical and functional association of the major histocompatibility complex class I heavy chain alpha3 domain with the transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Tapasin enhances assembly of transporters associated with antigen processing-dependent and -independent peptides with HLA-A2 and HLA-B27 expressed in insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Evidence for successive peptide binding and quality control stages during MHC class I assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line .220.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Cloning and functional characterization of a subunit of the transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Peptide-bound major histocompatibility complex class I molecules associate with tapasin before dissociation from transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Tapasin is required for efficient peptide binding to transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Regulation of transporter associated with antigen processing by phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

ER60/ERp57 forms disulfide-bonded intermediates with MHC class I heavy chain

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Lateral diffusion of GFP-tagged H2Ld molecules and of GFP-TAP1 reports on the assembly and retention of these molecules in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Generation and TAP-mediated transport of peptides for major histocompatibility complex class I molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Kb, Kd, and Ld molecules share common tapasin dependencies as determined using a novel epitope tag.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Thermal stability of MHC class I-beta 2-microglobulin peptide complexes in the endoplasmic reticulum is determined by the peptide occupancy of the transporter associated with antigen processing complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Mechanisms of MHC class I--restricted antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Assembly of tapasin-associated MHC class I in the absence of the transporter associated with antigen processing (TAP).

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

A point mutation in HLA-A*0201 results in failure to bind the TAP complex and to present virus-derived peptides to CTL.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Distinct functions of tapasin revealed by polymorphism in MHC class I peptide loading

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Cutting edge: Tapasin is retained in the endoplasmic reticulum by dynamic clustering and exclusion from endoplasmic reticulum exit sites

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Major histocompatibility complex class I molecules interact with both subunits of the transporter associated with antigen processing, TAP1 and TAP2.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Calnexin expression does not enhance the generation of MHC class I-peptide complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Endogenous and exogenous factors contributing to the surface expression of HLA B27 on mutant APC.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Quantitative and qualitative influences of tapasin on the class I peptide repertoire.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Calnexin retains unassembled major histocompatibility complex class I free heavy chains in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

The major substrates for TAP in vivo are derived from newly synthesized proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Assembly, peptide loading, and transport of MHC class I molecules in a calnexin-negative cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Retention of empty MHC class I molecules by tapasin is essential to reconstitute antigen presentation in invertebrate cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Characterization of class I MHC folding intermediates and their disparate interactions with peptide and beta 2-microglobulin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Interaction of MHC class I molecules with the transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

MHC class I molecules form ternary complexes with calnexin and TAP and undergo peptide-regulated interaction with TAP via their extracellular domains

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Beta 2-microglobulin and calnexin can independently promote folding and disulfide bond formation in class I histocompatibility proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

HLA-B polymorphism affects interactions with multiple endoplasmic reticulum proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

A region of tapasin that affects L(d) binding and assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Disparate binding of chaperone proteins by HLA-A subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Calreticulin binds to the alpha1 domain of MHC class I independently of tapasin

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Deglucosylation of N-linked glycans is an important step in the dissociation of calreticulin-class I-TAP complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Definition and transfer of a serological epitope specific for peptide-empty forms of MHC class I.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021

Calnexin recognizes carbohydrate and protein determinants of class I major histocompatibility complex molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900103-7

7 January 2021