Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines (Q28218528)

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Azusa Shinohara

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Toshie Gamou

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Masaki Saito

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Akihiro Iwamatsu

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Ryuichi Sakai

Megabase-scale analysis of the origin of N-myc amplicons in human neuroblastomas

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language of work or name

English

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publication date

29 August 2002

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5823-34

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cites work

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Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

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Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain

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Shc signaling in differentiating neural progenitor cells

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Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

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Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

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Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

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Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

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Human N-myc is closely related in organization and nucleotide sequence to c-myc

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Expression of the ALK tyrosine kinase gene in neuroblastoma

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Affinity, specificity, and kinetics of the interaction of the SHC phosphotyrosine binding domain with asparagine-X-X-phosphotyrosine motifs of growth factor receptors

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Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

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An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells

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N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling

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Binding specificity and mutational analysis of the phosphotyrosine binding domain of the brain-specific adaptor protein ShcC.

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A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain

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ALK as a novel lymphoma-associated tumor antigen: identification of 2 HLA-A2.1-restricted CD8+ T-cell epitopes

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SH2 domains, interaction modules and cellular wiring

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

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Human-tumor-derived cell lines contain common and different transforming genes

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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Characterization of the kinase activity essential for tyrosine phosphorylation of p130Cas in fibroblasts

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Nucleotide sequence of the human N-myc gene

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Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin

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Alternative expression of Shc family members in nerve-injured motoneurons

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The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

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A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

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Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma.

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7 January 2021

Systematic peptide fragmentation of polyvinylidene difluoride(PVDF)-immobilized proteins prior to microsequencing

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7 January 2021

Prognostic indicators for neuroblastoma: stage, grade, DNA ploidy, MIB-1-proliferation index, p53, HER-2/neu and EGFr--a survival study

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Induction of terminal differentiation and apoptosis in human colonic carcinoma cells by brefeldin A, a drug affecting ganglioside biosynthesis

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The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons

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Long range periodicities in mouse satellite DNA

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