Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2 (Q28199348)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11390377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2 (English)

1 reference

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TNFAIP3 interacting protein 2

8 November 2019

main subject

1 reference

Tumor necrosis factor, alpha-induced protein 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11390377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

S Van Huffel

1 reference

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8 November 2019

F Delaei

series ordinal

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8 November 2019

K Heyninck

series ordinal

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8 November 2019

D De Valck

series ordinal

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8 November 2019

language of work or name

English

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publication date

4 June 2001

1 reference

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Journal of Biological Chemistry

8 November 2019

published in

1 reference

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8 November 2019

volume

276

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8 November 2019

issue

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8 November 2019

page(s)

30216-30223

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Activators and target genes of Rel/NF-kappaB transcription factors

8 November 2019

cites work

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-kappaB.

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Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines

21 January 2018

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NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2

21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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Identification and characterization of an IkappaB kinase

21 January 2018

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

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The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

21 January 2018

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

21 January 2018

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Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

21 January 2018

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An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways

21 January 2018

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Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

21 January 2018

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The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

21 January 2018

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Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

21 January 2018

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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

21 January 2018

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MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

21 January 2018

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A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism

21 January 2018

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

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A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis

21 January 2018

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The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

21 January 2018

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The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6

21 January 2018

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The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

21 January 2018

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Functional redundancy of the zinc fingers of A20 for inhibition of NF-kappaB activation and protein-protein interactions

21 January 2018

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A20, an inhibitor of cell death, self-associates by its zinc finger domain

21 January 2018

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A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins

21 January 2018

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Optimization of experimental variables influencing reporter gene expression in hepatoma cells following calcium phosphate transfection

21 January 2018

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

21 January 2018

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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21 January 2018

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Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

21 January 2018

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Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

21 January 2018

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Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2

21 January 2018

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A20 zinc finger protein inhibits TNF-induced apoptosis and stress response early in the signaling cascades and independently of binding to TRAF2 or 14-3-3 proteins.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M100048200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11390377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11390377%20AND%20SRC:MED&resulttype=core&format=json