Receptor downregulation and multivesicular-body sorting (Q28131720)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0032510

endosome transport via multivesicular body sorting pathway

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0032509

late endosome to vacuole transport via multivesicular body sorting pathway

1 reference

Gene Ontology release 2020-05-02

Greg Odorizzi

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David J Katzmann

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Scott D Emr

series ordinal

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language of work or name

English

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publication date

December 2002

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published in

Nature Reviews Molecular Cell Biology

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volume

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issue

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page(s)

893-905

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cites work

The endocytic pathway: a mosaic of domains

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Endocytosis and molecular sorting

31 March 2020

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A small particulate component of the cytoplasm

31 March 2020

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An electron microscope study of the rat ovum.

31 March 2020

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Vesicle fusion and formation at the surface of pinocytic vacuoles in macrophages

31 March 2020

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Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts

31 March 2020

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Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431

31 March 2020

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Localization of the epidermal growth factor (EGF) receptor within the endosome of EGF-stimulated epidermoid carcinoma (A431) cells

31 March 2020

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Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

31 March 2020

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Compartmentalized signal transduction by receptor tyrosine kinases

31 March 2020

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Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes

31 March 2020

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Pool of ligand‐bound platelet‐derived growth factor β‐receptors remain activated and tyrosine phosphorylated after internalization

31 March 2020

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Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation

31 March 2020

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Regulation of signal transduction by endocytosis

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Endocytosis and mitogenic signaling

31 March 2020

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Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

31 March 2020

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The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

31 March 2020

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Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

31 March 2020

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Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

31 March 2020

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A function for monoubiquitination in the internalization of a G protein-coupled receptor

31 March 2020

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Monoubiquitin carries a novel internalization signal that is appended to activated receptors

31 March 2020

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Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase.

31 March 2020

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Uptake of the ATP-binding cassette (ABC) transporter Ste6 into the yeast vacuole is blocked in the doa4 Mutant

31 March 2020

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Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae

31 March 2020

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Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease

31 March 2020

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Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

31 March 2020

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The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

31 March 2020

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

31 March 2020

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The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

31 March 2020

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Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

31 March 2020

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

31 March 2020

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RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

31 March 2020

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Ubiquitin-independent entry into the yeast recycling pathway

31 March 2020

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Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

31 March 2020

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Epidermal growth factor induces ubiquitination of Eps15.

31 March 2020

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A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

31 March 2020

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

31 March 2020

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

31 March 2020

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Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

31 March 2020

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

31 March 2020

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Ubiquitin Sorts Proteins into the Intralumenal Degradative Compartment of the Late-Endosome/Vacuole

31 March 2020

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Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

31 March 2020

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A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

31 March 2020

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The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast

31 March 2020

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The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways

31 March 2020

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Role of Cue1p in ubiquitination and degradation at the ER surface

31 March 2020

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The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

31 March 2020

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Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

31 March 2020

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A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

31 March 2020

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TSG101 may be the prototype of a class of dominant negative ubiquitin regulators

31 March 2020

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Identification of homer as a homologue of the Wiskott-Aldrich syndrome protein suggests a receptor-binding function for WH1 domains

31 March 2020

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Multiple sorting pathways between the late Golgi and the vacuole in yeast

31 March 2020

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Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant

31 March 2020

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Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

31 March 2020

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Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

31 March 2020

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Structure and functional interactions of the Tsg101 UEV domain

31 March 2020

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Yeast mutants affecting possible quality control of plasma membrane proteins

31 March 2020

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ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking

31 March 2020

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Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

31 March 2020

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Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

31 March 2020

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The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

31 March 2020

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Hrs recruits clathrin to early endosomes

31 March 2020

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Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes

31 March 2020

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The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

31 March 2020

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Sorting of mannose 6-phosphate receptors mediated by the GGAs

31 March 2020

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Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains

31 March 2020

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Structural basis for recognition of acidic-cluster dileucine sequence by GGA1

31 March 2020

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Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

31 March 2020

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Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors

31 March 2020

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The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.

31 March 2020

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Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

31 March 2020

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A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase

31 March 2020

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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

31 March 2020

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Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p

31 March 2020

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A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

31 March 2020

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Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

31 March 2020

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Phosphoinositide signaling and the regulation of membrane trafficking in yeast

31 March 2020

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Location, location, location: membrane targeting directed by PX domains

31 March 2020

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SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

31 March 2020

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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

31 March 2020

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Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities

31 March 2020

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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

31 March 2020

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Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity

31 March 2020

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Human VPS34 is required for internal vesicle formation within multivesicular endosomes

31 March 2020

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Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis

31 March 2020

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Notch signaling: cell fate control and signal integration in development

31 March 2020

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Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development

31 March 2020

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

31 March 2020

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Nuclear access and action of notch in vivo

31 March 2020

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Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling.

31 March 2020

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Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta

31 March 2020

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neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

31 March 2020

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Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

31 March 2020

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Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

31 March 2020

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Ubiquitination of HIV-1 and MuLV Gag.

31 March 2020

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Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2

31 March 2020

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A role for ubiquitin ligase recruitment in retrovirus release

31 March 2020

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HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

31 March 2020

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Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

31 March 2020

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Ubiquitin and the control of protein fate in the secretory and endocytic pathways

31 March 2020

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

31 March 2020

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

31 March 2020

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Recognition of the polyubiquitin proteolytic signal

31 March 2020

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Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.

31 March 2020

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Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease

31 March 2020

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The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole

31 March 2020

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The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.

31 March 2020

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Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast

31 March 2020

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The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

31 March 2020

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Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor beta chain to late endocytic compartments

31 March 2020

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Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

31 March 2020

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Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

31 March 2020

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Dimensions Publication ID

31 March 2020

Identifiers

DOI

10.1038/NRM973

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1015443502

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Fatcat ID

release_5ufg7rmfdzc23h73l3bylzu7py

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Fatcat

https://api.fatcat.wiki/v0/release/5ufg7rmfdzc23h73l3bylzu7py