Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance (Q27655357)

Guillaume Stewart-Jones

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Mikkel Harndahl

Mikkel Harndahl

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Astrid K. N. Iversen

Astrid K N Iversen

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Andrew James McMichael

Andrew J McMichael

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Lars Fugger

Lars Fugger

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Yvonne Jones

E Yvonne Jones

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Soren Buus

Søren Buus

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Edmund Wee

Edmund Wee

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Jan Gerstoft

Jan Gerstoft

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author name string

Anne Burgevin

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Lone Friis

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Kasper Lamberth

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Chih-hao Chang

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Mirjana Weimershaus

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Nadja Akkad

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Hansjörg Schild

Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses

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language of work or name

English

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publication date

June 2009

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636-46

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cites work

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1728

Quantitative analysis of prion-protein degradation by constitutive and immuno-20S proteasomes indicates differences correlated with disease susceptibility

21 January 2018

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https://api.crossref.org/works/10.1038%2FNI.1728

CD8+ T cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNI.1728

Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

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12 December 2020

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.

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12 December 2020

A subset of HLA-B27 molecules contains peptides much longer than nonamers

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12 December 2020

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

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12 December 2020

Contribution of proline residue for efficient production of MHC class I ligands by proteasomes

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12 December 2020

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

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12 December 2020

Identification of self peptides bound to purified HLA-B27

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12 December 2020

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

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12 December 2020

Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer

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12 December 2020

Establishment of a quantitative ELISA capable of determining peptide - MHC class I interaction

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12 December 2020

Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses

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12 December 2020

Evolution and transmission of stable CTL escape mutations in HIV infection

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12 December 2020

Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific.

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12 December 2020

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

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12 December 2020

Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products

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12 December 2020

Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome

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12 December 2020

The peptide-binding motif for the human transporter associated with antigen processing

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12 December 2020

Three-dimensional structure of a peptide extending from one end of a class I MHC binding site

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12 December 2020

A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

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12 December 2020

Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles

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12 December 2020

Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay

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12 December 2020

Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication

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12 December 2020

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

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12 December 2020

Substrate selection by transporters associated with antigen processing occurs during peptide binding to TAP.

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12 December 2020

Impact of MHC class I diversity on immune control of immunodeficiency virus replication

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12 December 2020

Putative immunodominant human immunodeficiency virus-specific CD8(+) T-cell responses cannot be predicted by major histocompatibility complex class I haplotype

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12 December 2020

Physical association between MHC class I molecules and immunogenic peptides

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12 December 2020

Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.

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12 December 2020

Precise identification of a human immunodeficiency virus type 1 antigen processing mutant

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12 December 2020

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

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12 December 2020

T cell cross-reactivity and conformational changes during TCR engagement

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12 December 2020

Structural basis for degenerate recognition of natural HIV peptide variants by cytotoxic lymphocytes

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12 December 2020

Antigen processing by the proteasome

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12 December 2020

Portable flanking sequences modulate CTL epitope processing

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12 December 2020

Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27.

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12 December 2020

AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis

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12 December 2020

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope

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12 December 2020

A detailed analysis of the murine TAP transporter substrate specificity

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12 December 2020

Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1

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12 December 2020

HIV and SIV CTL escape: implications for vaccine design

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12 December 2020

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

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12 December 2020

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

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12 December 2020

Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum

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12 December 2020

Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection

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12 December 2020

Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

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12 December 2020

Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection

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12 December 2020