Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation (Q27640501)

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Molecular virology of hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Influence of viral quasispecies on effectiveness of interferon therapy in chronic hepatitis C patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C.

7 January 2021

1 reference

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Candidate targets for hepatitis C virus-specific antiviral therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Molecular targets for AIDS therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Closing in on HIV drug resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

7 January 2021

1 reference

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

De novo RNA synthesis catalyzed by HCV RNA-dependent RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

A mechanism for initiating RNA-dependent RNA polymerization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

A protein covalently linked to poliovirus genome RNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: purification and enzymatic analysis of the RNA-dependent RNA polymerase 3D(pol).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

A detailed model of reverse transcription and tests of crucial aspects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Only a small fraction of purified hepatitis C RNA-dependent RNA polymerase is catalytically competent: implications for viral replication and in vitro assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Measurement of HCV RdRp activity with C-terminal 21 aa truncated NS5b protein: optimization of assay conditions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Expression of hepatitis C virus NS5B protein: characterization of its RNA polymerase activity and RNA binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Structure of the RNA-dependent RNA polymerase of poliovirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Implementation of molecular replacement in AMoRe

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Oligomeric structures of poliovirus polymerase are important for function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the hepatitis C virus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Temperature-dependent equilibrium between the open and closed conformation of the p66 subunit of HIV-1 reverse transcriptase revealed by site-directed spin labelling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Solvent content of protein crystals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Processing of X-ray diffraction data collected in oscillation mode

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Raster3D Version 2.0. A program for photorealistic molecular graphics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Selection of 3'-template bases and initiating nucleotides by hepatitis C virus NS5B RNA-dependent RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0

Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901439-0