Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections (Q27023470)

Expert Review of Vaccines

1 March 2014

4 references

23 March 2019

20 June 2019

24 June 2019

28 May 2020

5 references

23 March 2019

20 June 2019

24 June 2019

28 May 2020

1 reference

1 reference

321-31

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Creative Commons Attribution-NonCommercial 3.0 Unported

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23 March 2019

20 June 2019

24 June 2019

on focus list of Wikimedia project

28 May 2020

ScienceSource

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21 March 2017

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Ascaris suum draft genome

21 March 2017

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21 March 2017

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21 March 2017

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21 March 2017

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

21 March 2017

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Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis

21 March 2017

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Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm

21 March 2017

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How effective is school-based deworming for the community-wide control of soil-transmitted helminths?

21 March 2017

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Genomic-bioinformatic analysis of transcripts enriched in the third-stage larva of the parasitic nematode Ascaris suum

21 March 2017

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Soil-transmitted helminth infections: updating the global picture

21 March 2017

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7 April 2017

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Molecular characterization of Trichinella spiralis aminopeptidase and its potential as a novel vaccine candidate antigen against trichinellosis in BALB/c mice

28 September 2017

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Global trends in neglected tropical disease control and elimination: impact on child health

28 September 2017

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Rapid re-infection with soil-transmitted helminths after triple-dose albendazole treatment of school-aged children in Yunnan, People's Republic of China

28 September 2017

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The Human Hookworm Vaccine

28 September 2017

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A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae.

28 September 2017

1 reference

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Cloning, expression and characterization of a Trichinella spiralis serine protease gene encoding a 35.5 kDa protein

28 September 2017

1 reference

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Screening of early antigen genes of adult-stage Trichinella spiralis using pig serum from different stages of early infection

28 September 2017

1 reference

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Vaccination of mice with an antigenic serine protease-like protein elicits a protective immune response against Trichinella spiralis infection.

28 September 2017

1 reference

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Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome

28 September 2017

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Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects

28 September 2017

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Trichuris muris: a model of gastrointestinal parasite infection

28 September 2017

1 reference

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Phylogenetic evidence that two distinct Trichuris genotypes infect both humans and non-human primates

28 September 2017

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Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR.

28 September 2017

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Genetic diversity of Ascaris in southwestern Uganda

28 September 2017

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Helminth parasites in pigs: new challenges in pig production and current research highlights

28 September 2017

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Identification and characterization of protective epitope of Trichinella spiralis paramyosin

28 September 2017

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The potential economic value of a hookworm vaccine

28 September 2017

1 reference

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The presence of serum anti-Ascaris lumbricoides IgE antibodies and of Trichuris trichiura infection are risk factors for wheezing and/or atopy in preschool-aged Brazilian children

28 September 2017

1 reference

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Ascaris suum: RNAi mediated silencing of enolase gene expression in infective larvae

28 September 2017

1 reference

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Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review

28 September 2017

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Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus

28 September 2017

1 reference

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Characterisation of the protective immune response following subcutaneous vaccination of susceptible mice against Trichuris muris

28 September 2017

1 reference

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Characterisation of effector mechanisms at the host:parasite interface during the immune response to tissue-dwelling intestinal nematode parasites

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Antigen selection for future anti-Trichuris vaccines: a comparison of cytokine and antibody responses to larval and adult antigen in a primary infection.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Species-specific antibody responses to the recombinant 53-kilodalton excretory and secretory proteins in mice infected with Trichinella spp.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Hookworm vaccines: past, present, and future

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Antigens from Ascaris suum trigger in vitro macrophage NO production.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Mice intranasally immunized with a recombinant 16-kilodalton antigen from roundworm Ascaris parasites are protected against larval migration of Ascaris suum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Intranasal immunization with recombinant Ascaris suum 14-kilodalton antigen coupled with cholera toxin B subunit induces protective immunity to A. suum infection in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Natural immunity to Ascaris lumbricoides associated with immunoglobulin E antibody to ABA-1 allergen and inflammation indicators in children.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Some gastro-intestinal parasites of zoonotic (public health) importance commonly observed in old world non-human primates in Kenya

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Structural and functional analysis of a glutathione S-transferase from Ascaris suum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

The effect of immunization of pigs with Ascaris suum cuticle components on the development of resistance to parenteral migration during a challenge infection.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Efficacy of oral vaccination against the murine intestinal parasite Trichuris muris is dependent upon host genetics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

An ultraviolet-attenuated egg vaccine for swine ascariasis: parameters affecting the development of protective immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Seasonal pneumonitis with eosinophilia. A study of larval ascariasis in Saudi Arabs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Ascaris suum: protective immunity in pigs immunized with products from eggs and larvae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Helminth infections of humans: mathematical models, population dynamics, and control.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Ascaris suum: development of intestinal immunity to infective second-stage larvae in swine.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Molecular cloning and partial characterization of a nematode-specific 24 kDa protein from Ascaris suum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Genetic structure and epidemiology of Ascaris populations: patterns of host affiliation in Guatemala

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Antigenic cross-reactivity between the human whipworm, Trichuris trichiura, and the mouse trichuroids Trichuris muris and Trichinella spiralis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Ascaris suum enolase is a potential vaccine candidate against ascariasis

31 May 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

21 January 2018

Ascaris and ascariasis

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

Resistance against migrating ascaris suum larvae in pigs immunized with infective eggs or adult worm antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

Immunization of rabbits with nematode Ascaris lumbricoides antigens induces antibodies cross-reactive to house dust mite Dermatophagoides farinae antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

Pig Ascaris: an important source of human ascariasis in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

Cloning and characterisation of a highly immunoreactive 37 kDa antigen with multi-immunoglobulin domains from the swine roundworm Ascaris suum

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

A DNA vaccine co-expressing Trichinella spiralis MIF and MCD-1 with murine ubiquitin induces partial protective immunity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

Oral vaccination with Ts87 DNA vaccine delivered by attenuated Salmonella typhimurium elicits a protective immune response against Trichinella spiralis larval challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.2014.872035

[Construction of expression vector of ALAg and immune protection of its recombinant protein induced in mice].

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

The ABA-1 allergen of Ascaris lumbricoides: sequence polymorphism, stage and tissue-specific expression, lipid binding function, and protein biophysical properties

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934375

Soil-transmitted helminthiases: number of children treated in 2011

28 November 2018

1 reference

12 December 2020

Identification of surface proteins and antigens from larval stages of Ascaris suum by two-dimensional electrophoresis

1 reference

12 December 2020

The effect of challenge and trickle Trichuris muris infections on the polarisation of the immune response

1 reference

12 December 2020

Human Trichuris-specific antibody responses in vaccinated hu-PBL-SCID mice

1 reference

12 December 2020

Functional antigens of Trichuris muris. The stimulation of immunity by vaccination of mice with somatic antigen preparations

1 reference

12 December 2020

Immunization of pigs against experimental Ascaris suum infection by feeding ultraviolet-attenuated eggs

1 reference

12 December 2020

Specific cross-immunity between Trichinella spiralis and Trichuris muris: immunization with heterologous infections and antigens and transfer of immunity with heterologous immune mesenteric lymph node cells

1 reference

12 December 2020

Ascaris suum--vaccination of mice with liposome encapsulated antigen

1 reference

12 December 2020

Comparative study of Trichuris trichiura from non-human primates and from man, and their difference with T. suis

1 reference

12 December 2020

Identification and characterization of excreted/secreted products of Trichuris trichiura

1 reference

12 December 2020

High levels of protection induced by a 40-mer synthetic peptide vaccine against the intestinal nematode parasite Trichinella spiralis

1 reference

12 December 2020

Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion

1 reference

12 December 2020

Vaccination with recombinant Ascaris suum 24-kilodalton antigen induces a Th1/Th2-mixed type immune response and confers high levels of protection against challenged Ascaris suum lung-stage infection in BALB/c mice

1 reference

12 December 2020

Production of Ascaris suum As14 protein and its fusion protein with cholera toxin B subunit in rice seeds

1 reference

12 December 2020

10.1586/14760584.2014.872035

Identifiers

DOI

1 reference

1 reference

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PubMed publication ID

24392641

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