Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin (Q24652731)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19011242%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin (English)

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17 January 2020

0 references

1 reference

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17 January 2020

Min Chen

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17 January 2020

Mala Sinha

series ordinal

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17 January 2020

Bruce A Luxon

series ordinal

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17 January 2020

Anne R Bresnick

series ordinal

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17 January 2020

language of work or name

English

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publication date

14 November 2008

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17 January 2020

number of pages

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

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17 January 2020

volume

284

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17 January 2020

issue

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17 January 2020

page(s)

1484-1494

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The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells

17 January 2020

cites work

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7 April 2017

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Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression

7 April 2017

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S100A4, a mediator of metastasis

7 April 2017

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7 April 2017

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Characterization of the metastasis-associated protein, S100A4. Roles of calcium binding and dimerization in cellular localization and interaction with myosin

7 April 2017

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S100A7, S100A10, and S100A11 are transglutaminase substrates

7 April 2017

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28 September 2017

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Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition

28 September 2017

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LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells

28 September 2017

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Upregulation and redistribution of integrin alpha6beta4 expression occurs at an early stage in pancreatic adenocarcinoma progression

28 September 2017

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Ras stimulation of E2F activity and a consequent E2F regulation of integrin alpha6beta4 promote the invasion of breast carcinoma cells

28 September 2017

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p63 regulates an adhesion programme and cell survival in epithelial cells

28 September 2017

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Identification of large-scale molecular changes of Autotaxin(ENPP2) knock-down by small interfering RNA in breast cancer cells

28 September 2017

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NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2.

28 September 2017

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PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer

28 September 2017

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Beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis

28 September 2017

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Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells

28 September 2017

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28 September 2017

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Critical regulation of genes for tumor cell migration by AP-1.

28 September 2017

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The Met receptor and alpha 6 beta 4 integrin can function independently to promote carcinoma invasion

28 September 2017

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Lineage infidelity of MDA-MB-435 cells: expression of melanocyte proteins in a breast cancer cell line

28 September 2017

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S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis

28 September 2017

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Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors

28 September 2017

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ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma.

28 September 2017

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Further evidence to support the melanocytic origin of MDA-MB-435

28 September 2017

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beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

28 September 2017

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A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism

28 September 2017

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Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells

28 September 2017

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Structure and function of hemidesmosomes: more than simple adhesion complexes

28 September 2017

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Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells

28 September 2017

1 reference

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Modulation of myoepithelial-associated alpha6beta4 integrin in a breast cancer cell line alters invasive potential

28 September 2017

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Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours

28 September 2017

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Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance

28 September 2017

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Expression of the alpha6beta4 integrin provides prognostic information in bladder cancer.

30 May 2018

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The intracellular functions of alpha6beta4 integrin are regulated by EGF.

30 May 2018

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The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.

30 May 2018

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Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice

30 May 2018

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Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells

30 May 2018

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Crossref

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Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

21 January 2018

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The S100A4 Metastasis Factor Regulates Cellular Motility via a Direct Interaction with Myosin-IIA

21 January 2018

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The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis.

21 January 2018

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Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines

28 November 2018

1 reference

12 December 2020

High expression level of alpha 6 integrin in human breast carcinoma is correlated with reduced survival

1 reference

12 December 2020

Effect of mts1 (S100A4) expression on the progression of human breast cancer cells

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12 December 2020

Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene

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12 December 2020

Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer

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12 December 2020

Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion

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12 December 2020

Prognostic value of alpha 6 beta 4 integrin expression in breast carcinomas is affected by laminin production from tumor cells

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12 December 2020

Increased levels of alpha6 integrins are associated with the metastatic phenotype of human breast cancer cells

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12 December 2020

Identifiers

DOI

10.1074/JBC.M803997200

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19011242%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19011242%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19011242

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19011242%20AND%20SRC:MED&resulttype=core&format=json