TRPM2 links oxidative stress to NLRP3 inflammasome activation (Q24600251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23511475%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

TRPM2 links oxidative stress to NLRP3 inflammasome activation (English)

1 reference

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26 February 2020

1 reference

0 references

1 reference

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26 February 2020

Zhenyu Zhong

1 reference

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26 February 2020

Yougang Zhai

1 reference

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26 February 2020

Shuang Liang

1 reference

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26 February 2020

Yasuo Mori

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23511475%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Fayyaz S Sutterwala

1 reference

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26 February 2020

Liang Qiao

1 reference

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26 February 2020

language of work or name

English

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publication date

1 January 2013

1 reference

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26 February 2020

published in

Nature Communications

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26 February 2020

volume

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26 February 2020

page(s)

1611

1 reference

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

26 February 2020

cites work

1 reference

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

7 April 2017

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

7 April 2017

1 reference

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TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

7 April 2017

1 reference

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

7 April 2017

1 reference

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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

7 April 2017

1 reference

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Charge compensation during the phagocyte respiratory burst

7 April 2017

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A role for mitochondria in NLRP3 inflammasome activation

7 April 2017

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Gout-associated uric acid crystals activate the NALP3 inflammasome

7 April 2017

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

7 April 2017

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Cryopyrin activates the inflammasome in response to toxins and ATP

7 April 2017

1 reference

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ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

7 April 2017

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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

7 April 2017

1 reference

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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

7 April 2017

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Inflammasomes in health and disease

7 April 2017

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Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

7 April 2017

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The inflammasome NLRs in immunity, inflammation, and associated diseases

7 April 2017

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

7 April 2017

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NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

7 April 2017

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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

7 April 2017

1 reference

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

7 April 2017

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Critical role for calcium mobilization in activation of the NLRP3 inflammasome

7 April 2017

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Liposomal drug formulations in cancer therapy: 15 years along the road

27 September 2017

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The inflammasome: an integrated view

27 September 2017

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Liposomes: from a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine.

27 September 2017

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Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

27 September 2017

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Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome

27 September 2017

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Mitochondria in innate immune responses

27 September 2017

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Mitochondria: Sovereign of inflammation?

27 September 2017

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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

27 September 2017

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Inflammasomes and autoimmunity

27 September 2017

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TRPM2: a multifunctional ion channel for calcium signalling.

27 September 2017

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The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

27 September 2017

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Molecular mechanism of NLRP3 inflammasome activation

27 September 2017

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Voltage-gated proton channels find their dream job managing the respiratory burst in phagocytes

27 September 2017

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Malarial hemozoin is a Nalp3 inflammasome activating danger signal

27 September 2017

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CA-074Me protection against anthrax lethal toxin

27 September 2017

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Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

27 September 2017

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Cationic liposomes as vaccine adjuvants

27 September 2017

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Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokines

27 September 2017

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The inflammasome: first line of the immune response to cell stress

27 September 2017

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Female genital tract immunization: evaluation of candidate immunoadjuvants on epithelial cell secretion of CCL20 and dendritic/Langerhans cell maturation

27 September 2017

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Immunostimulation mechanism of LPD nanoparticle as a vaccine carrier.

27 September 2017

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TRPM2 Ca2+ channel regulates energy balance and glucose metabolism

27 September 2017

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Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

30 May 2018

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Biochemical effects of the hypoglycaemic compound diphenyleneiodonnium. Catalysis of anion-hydroxyl ion exchange across the inner membrane of rat liver mitochondria and effects on oxygen uptake

30 May 2018

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Dihydroisoquinolinones: the design and synthesis of a new series of potent inhibitors of poly(ADP-ribose) polymerase

30 May 2018

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Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

30 May 2018

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The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels

21 January 2018

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Measurement of sub-membrane [Ca2+] in adult myofibers and cytosolic [Ca2+] in myotubes from normal and mdx mice using the Ca2+ indicator FFP-18.

21 January 2018

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Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury.

21 January 2018

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Liposomes as immunological adjuvants

28 November 2018

1 reference

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Mitochondrial control of the NLRP3 inflammasome

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23511475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23511475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunostimulation of dendritic cells by cationic liposomes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23511475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS2608

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23511475%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

26 February 2020

ADS bibcode

2013NatCo...4.1611Z

0 references

1049295717

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23511475%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

23511475

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23511475%20AND%20SRC:MED&resulttype=core&format=json