Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle (Q24555189)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11572976%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle (English)

1 reference

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11 November 2019

author

Bruce William Stillman

series ordinal

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11 November 2019

M Weinreich

1 reference

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11 November 2019

C Liang

series ordinal

1 reference

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11 November 2019

H H Chen

series ordinal

1 reference

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11 November 2019

language of work or name

English

0 references

publication date

1 September 2001

1 reference

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11 November 2019

number of pages

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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11 November 2019

volume

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11 November 2019

issue

1 reference

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11 November 2019

page(s)

11211-11217

1 reference

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DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p

11 November 2019

cites work

1 reference

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Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

24 March 2017

1 reference

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Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

24 March 2017

1 reference

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Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.

24 March 2017

1 reference

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mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cyclin-binding motifs are essential for the function of p21CIP1

24 March 2017

1 reference

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Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

24 March 2017

1 reference

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Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control

24 March 2017

1 reference

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Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

24 March 2017

1 reference

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Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7.

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

CLB5-dependent activation of late replication origins in S. cerevisiae.

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cdc7 is required throughout the yeast S phase to activate replication origins.

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Elevated recombination rates in transcriptionally active DNA

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Initiating DNA synthesis: from recruiting to activating the MCM complex

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Initiation of DNA replication in eukaryotic cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cell cycle checkpoints: preventing an identity crisis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cdc6 cooperates with Sic1 and Hct1 to inactivate mitotic cyclin-dependent kinases.

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Stepwise assembly of initiation proteins at budding yeast replication origins in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cyclin B-cdk1 kinase stimulates ORC- and Cdc6-independent steps of semiconservative plasmid replication in yeast nuclear extracts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The Cdc7 protein kinase is required for origin firing during S phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cyclins and the wiring of the yeast cell cycle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cell cycle control of DNA replication.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Regulating S phase: CDKs, licensing and proteolysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M-phase checkpoint

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

Deregulated cyclin E induces chromosome instability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

DNA damage checkpoint in budding yeast.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The Cdc28 inhibitor p40SIC1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58709

The fission yeast cdc18+ gene product couples S phase to START and mitosis

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201387198

A BAC-based physical map of the major autosomes of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201387198

Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201387198

The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201387198

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201387198

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

21 January 2018

1 reference

12 December 2020

Cell cycle. License withheld--geminin blocks DNA replication

1 reference

12 December 2020

The cyclin-dependent kinase inhibitory domain of the yeast Sic1 protein is contained within the C-terminal 70 amino acids

1 reference

12 December 2020

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

1 reference

12 December 2020

CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis

1 reference

12 December 2020

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1 reference

12 December 2020

p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast

1 reference

12 December 2020

p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase

1 reference

12 December 2020

Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.201387198

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11572976%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

ADS bibcode

2001PNAS...9811211W

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11572976%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

11572976

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11572976%20AND%20SRC:MED&resulttype=core&format=json