Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase (Q24548452)

Minichromosome maintenance 5 Dmel_CG4082

1 reference

Minichromosome maintenance 7 Dmel_CG4978

1 reference

Minichromosome maintenance 6 Dmel_CG4039

1 reference

Partner of Sld Five 2 Dmel_CG18013

1 reference

Cell division cycle 45 Dmel_CG3658

1 reference

Partner of Sld Five 3 Dmel_CG2222

1 reference

Sld5 Dmel_CG14549

1 reference

Partner of Sld Five 1 Dmel_CG9187

1 reference

Minichromosome maintenance 2 Dmel_CG7538

1 reference

Proceedings of the National Academy of Sciences of the United States of America

Peter W Lewis

0 references

Michael R Botchan

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author name string

Stephen E Moyer

series ordinal

0 references

language of work or name

English

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publication date

5 July 2006

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published in

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volume

103

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issue

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page(s)

10236-41

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cites work

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A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

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Self-assembling protein microarrays

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Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation

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GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast

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Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae

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Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

24 March 2017

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Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity

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Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

24 March 2017

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Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.

24 March 2017

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The human homolog of Saccharomyces cerevisiae CDC45

24 March 2017

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A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

24 March 2017

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mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p

24 March 2017

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Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

24 March 2017

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GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

24 March 2017

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Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex.

24 March 2017

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S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

24 March 2017

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Uninterrupted MCM2-7 function required for DNA replication fork progression

24 March 2017

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Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication

24 March 2017

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Cold-sensitive cell-division-cycle mutants of yeast: isolation, properties, and pseudoreversion studies

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A group of interacting yeast DNA replication genes

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Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts

24 March 2017

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A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast

24 March 2017

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Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis

24 March 2017

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Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication

10 May 2017

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Pumps, paradoxes and ploughshares: mechanism of the MCM2-7 DNA helicase

27 September 2017

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Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

27 September 2017

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A novel intermediate in initiation complex assembly for fission yeast DNA replication.

27 September 2017

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Eukaryotic MCM proteins: beyond replication initiation

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Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates

27 September 2017

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A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication

27 September 2017

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Drosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replication

27 September 2017

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Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading

27 September 2017

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Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe

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The intrinsic DNA helicase activity of Methanobacterium thermoautotrophicum delta H minichromosome maintenance protein

27 September 2017

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A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase

27 September 2017

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The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum DeltaH contains DNA helicase activity

27 September 2017

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Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex

27 September 2017

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CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication

27 September 2017

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Identification of sna41 gene, which is the suppressor of nda4 mutation and is involved in DNA replication in Schizosaccharomyces pombe

27 September 2017

1 reference

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Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication.

30 May 2018

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Polymorphism and double hexamer structure in the archaeal minichromosome maintenance (MCM) helicase from Methanobacterium thermoautotrophicum.

28 November 2018

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DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process.

28 November 2018

1 reference

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CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482467

The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16798881

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biochemical function of mouse minichromosome maintenance 2 protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16798881

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0602400103

1 reference

ADS bibcode

2006PNAS..10310236M

0 references

1 reference

1 reference

PubMed publication ID

16798881

1 reference