Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2 (Q24530103)

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C Mitchelmore

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N Spodsberg

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A M Jensen

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O Norén

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H Sjöström

A homeodomain protein related to caudal regulates intestine-specific gene transcription

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language of work or name

English

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publication date

15 March 1997

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published in

Biochemical Journal

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volume

322 ( Pt 3)

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page(s)

833-8

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cites work

1 reference

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Studies on the expression of intestinal lactase in different individuals

24 March 2017

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Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme

24 March 2017

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Regulation of intestinal lactase in adult hypolactasia

24 March 2017

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Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast

24 March 2017

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The caudal-type homeobox protein Cdx-2 binds to the colon promoter of the carbonic anhydrase 1 gene

24 March 2017

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An intestine-specific homeobox gene regulates proliferation and differentiation

27 September 2017

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Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3.

27 September 2017

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Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.

27 September 2017

1 reference

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The cis-element CE-LPH1 of the rat intestinal lactase gene promoter interacts in vitro with several nuclear factors present in endodermal tissues

27 September 2017

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Further characterization of the 5'-flanking region of the rat lactase-phlorizin hydrolase gene

27 September 2017

1 reference

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A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor

27 September 2017

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Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase

27 September 2017

1 reference

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Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase

27 September 2017

1 reference

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Molecular basis of lactase levels in adult humans

27 September 2017

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Homeobox gene expression in the intestinal epithelium of adult mice

27 September 2017

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Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene

27 September 2017

1 reference

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Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

27 September 2017

1 reference

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Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Lactase-phlorizin hydrolase and aminopeptidase N are differentially regulated in the small intestine of the pig.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Structure of the murine homeobox gene cdx-2. Expression in embryonic and adult intestinal epithelium.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Coordinate expression of lactase-phlorizin hydrolase mRNA and enzyme levels in rat intestine during development

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Isolation and characterization of the human sucrase-isomaltase gene and demonstration of intestine-specific transcriptional elements

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

A novel intestinal trans-factor (NF-LPH1) interacts with the lactase-phlorizin hydrolase promoter and co-varies with the enzymatic activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

The rat LPH gene 5' region: comparative structure with the human gene

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Region-specific expression of multiple lactase-phlorizin hydrolase genes in intestine of rabbit

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Restriction of lactase gene expression along the proximal-to-distal axis of rat small intestine occurs during postnatal development.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

Transcriptional regulation of intestinal hydrolase biosynthesis during postnatal development in rats.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218263

The levels of lactase and of sucrase-isomaltase along the rabbit small intestine are regulated both at the mRNA level and post-translationally

29 November 2018

1 reference

12 December 2020

Onset of transcription of the aminopeptidase N (leukemia antigen CD 13) gene at the crypt/villus transition zone during rabbit enterocyte differentiation

1 reference

12 December 2020

Comparative expression of the mRNA for three intestinal hydrolases during postnatal development in the rat

1 reference

12 December 2020

Tissue-specific interactions between nuclear proteins and the aminopeptidase N promoter

1 reference

12 December 2020

Sucrase-isomaltase gene expression along crypt-villus axis of human small intestine is regulated at level of mRNA abundance

1 reference

12 December 2020

Messenger RNA sorting in enterocytes. Co-localization with encoded proteins

1 reference

12 December 2020

Lactase gene expression during early development of rat small intestine

1 reference

12 December 2020

1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice

1 reference

12 December 2020

The polymorphic expression of lactase in adults is regulated at the messenger RNA level

1 reference

12 December 2020

Mosaic regulation of lactase in human adult-type hypolactasia

1 reference

12 December 2020