A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses (Q24317413)

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English	A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses	scientific article

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scholarly article

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A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses (English)

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toll-like receptor

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regulation of interferon-alpha production

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Gene Ontology release 2020-05-02

Gene Ontology ID

positive regulation of interferon-alpha production

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Gene Ontology release 2020-05-02

Gene Ontology ID

negative regulation of interferon-alpha production

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GOA release 2020-03-11

negative regulation of chemokine (C-C motif) ligand 5 production

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GOA release 2020-03-11

author name string

J S Booth

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P J Griebel

2

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L A Babiuk

3

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G K Mutwiri

4

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language of work or name

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publication date

May 2009

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Mucosal Immunology

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2

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3

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265-75

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TLR3-, TLR7-, and TLR9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone marrow-derived mast cells

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Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities

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Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

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A case for regulatory B cells

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Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

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Swine Toll-like receptor 9(1) recognizes CpG motifs of human cell stimulant

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Toll-like receptors and innate immunity

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Toll-like receptors

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Toll-like receptor signaling in intestinal epithelial cells contributes to colonic homoeostasis.

1 reference

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Expression and function of Toll-like receptors in T lymphocytes

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CpG DNA-mediated immune response in pulmonary endothelial cells

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Identification and expression of Toll-like receptors 1-10 in selected bovine and ovine tissues.

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IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function.

1 reference

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Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination

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1 reference

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Structure and expression of ovine complement receptor type 2.

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Two B cell subpopulations have distinct recirculation characteristics

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B cell-deficient (mu MT) mice have alterations in the cytokine microenvironment of the gut-associated lymphoid tissue (GALT) and a defect in the low dose mechanism of oral tolerance

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1 reference

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1 reference

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1 reference

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1 reference

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