The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation (Q24316038)

Interferon regulatory factor 3

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transmembrane protein 173

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cellular response to exogenous dsRNA

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Yan-Yi Wang

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author name string

Bo Zhong

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Yan Yang

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Shu Li

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Ying Li

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Feici Diao

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Caoqi Lei

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Xiao He

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Lu Zhang

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Po Tien

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Hong-Bing Shu

Gene induction pathways mediated by distinct IRFs during viral infection.

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language of work or name

English

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publication date

17 October 2008

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538-50

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cites work

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TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

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Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

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RIGging an antiviral defense--it's in the CARDs.

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

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The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways

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The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

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