CAML is required for efficient EGF receptor recycling (Q24315767)

Calcium modulating ligand

GOA release 2020-03-11

1 reference

Epidermal growth factor receptor

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Jan van Deursen

Jan

van Deursen

1 reference

20 April 2024

David D Tran

David D

Tran

1 reference

20 April 2024

Helen R Russell

series ordinal

author given names

Helen R

author last names

Russell

1 reference

20 April 2024

Shari L Sutor

series ordinal

author given names

Shari L

author last names

Sutor

1 reference

20 April 2024

Richard J Bram

series ordinal

author given names

Richard J

author last names

Bram

1 reference

Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome

20 April 2024

language of work or name

English

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publication date

August 2003

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245-56

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cites work

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Regulation of signal transduction by endocytosis

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Characterization of the rebinding of 125I-epidermal growth factor released from BALB/c-3T3 cells following accumulation in the presence of chloroquine

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Endocytosis and signaling. an inseparable partnership

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Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog

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The role of tyrosine residues in fibroblast growth factor receptor 1 signaling in PC12 cells. Systematic site-directed mutagenesis in the endodomain

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Cellular localisation of human epidermal growth factor receptor

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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

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Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum

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Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

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A hydrophobic domain of Ca2+-modulating cyclophilin ligand modulates calcium influx signaling in T lymphocytes

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Co-localization of calcium-modulating cyclophilin ligand with intracellular calcium pools

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Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells

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EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain

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Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

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Enhanced degradation of EGF receptors by a sorting nexin, SNX1

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

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Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

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Accounting for specificity in receptor tyrosine kinase signaling

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Consumption of EGF by A431 cells: evidence for receptor recycling

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Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

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Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain

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Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells

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The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate

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Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways

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Recycling of epidermal growth factor in A431 cells

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NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily

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Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function

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Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

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