Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes (Q24309630)

GOA release 2020-03-11

author name string

G Flaggs

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A W Plug

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K M Dunks

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K E Mundt

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J C Ford

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M R Quiggle

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E M Taylor

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C H Westphal

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T Ashley

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M F Hoekstra

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A M Carr

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

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language of work or name

English

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publication date

1 December 1997

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977-86

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cites work

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Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

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A meiotic recombination checkpoint controlled by mitotic checkpoint genes

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Checkpoints: controls that ensure the order of cell cycle events

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Cell cycle control and cancer

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Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

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Cell cycle checkpoints: preventing an identity crisis

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

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cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

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A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage

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TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene

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TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

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The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair

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Isolation and characterization of the Schizosaccharomyces pombe rad3 gene, involved in the DNA damage and DNA synthesis checkpoints

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An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

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ATAXIA TELANGIECTASIA: An Inherited Human Disorder Involving Hypersensitivity to Ionizing Radiation and Related DNA-Damaging Chemicals

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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

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The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

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Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

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Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

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Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

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The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity

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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

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A drying-down technique for the spreading of mammalian meiocytes from the male and female germline

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

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RecA-like proteins are components of early meiotic nodules in lily

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Dissociation of the mouse testis and characterization of isolated spermatogenic cells

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Synaptonemal complex antigen location and conservation

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