Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction (Q24308600)

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English	Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction	scientific article

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scholarly article

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15 October 2019

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8622701%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

fibroblast growth factor receptor 1

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GOA release 2020-03-11

protein autophosphorylation

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GOA release 2020-03-11

Moosa Mohammadi

1

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15 October 2019

2

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15 October 2019

3

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15 October 2019

Joseph Schlessinger

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J Schlessinger

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15 October 2019

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W H Burgess

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15 October 2019

M Jaye

5

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15 October 2019

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1 March 1996

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15 October 2019

Molecular and Cellular Biology

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15 October 2019

16

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15 October 2019

3

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15 October 2019

977-989

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15 October 2019

The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Diverse forms of a receptor for acidic and basic fibroblast growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Fibroblast Growth Factor Receptors from Liver Vary in Three Structural Domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Crystal structure of the tyrosine kinase domain of the human insulin receptor

1 reference

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19 March 2017

Protein modules and signalling networks

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19 March 2017

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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19 March 2017

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Structural and functional diversity in the FGF receptor multigene family

1 reference

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19 March 2017

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

1 reference

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19 March 2017

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

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19 March 2017

Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1

1 reference

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19 March 2017

Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells

1 reference

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19 March 2017

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Fibroblast growth factor receptors have different signaling and mitogenic potentials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Autophosphorylation modulates the kinase activity and oncogenic potential of the Met receptor tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

19 March 2017

Oncogenes and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

7 April 2017

Detection and quantification of phosphotyrosine in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

7 April 2017

Growth factor signaling by receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

7 April 2017

SH2 and SH3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Identification of in vivo brain-derived neurotrophic factor-stimulated autophosphorylation sites on the TrkB receptor tyrosine kinase by site-directed mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Signalling by receptor tyrosine kinases

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27 September 2017

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

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27 September 2017

Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.

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27 September 2017

Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1.

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27 September 2017

Phosphorylation activates the insulin receptor tyrosine protein kinase

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27 September 2017

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

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27 September 2017

The heparin-binding (fibroblast) growth factor family of proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Heparin-binding growth factor 1 stimulates tyrosine phosphorylation in NIH 3T3 cells

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27 September 2017

The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

High-affinity binding and activation of a truncated FGF receptor by both aFGF and bFGF

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27 September 2017

Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions

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27 September 2017

Ligand-induced transphosphorylation between different FGF receptors

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27 September 2017

Proteins with SH2 domains: transducers in the tyrosine kinase signaling pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

1 reference

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27 September 2017

A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Fibroblast growth factor receptor-1 regulation of Src family kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Identification of TrkB autophosphorylation sites and evidence that phospholipase C-gamma 1 is a substrate of the TrkB receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

27 September 2017

Phospholipase C gamma activation, phosphotidylinositol hydrolysis, and calcium mobilization are not required for FGF receptor-mediated chemotaxis.

1 reference

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27 September 2017

Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites

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30 May 2018

Identification of tyrosines 154 and 307 in the extracellular domain and 653 and 766 in the intracellular domain as phosphorylation sites in the heparin-binding fibroblast growth factor receptor tyrosine kinase (flg).

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30 May 2018

Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor).

1 reference

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30 May 2018

Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF

1 reference

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30 May 2018

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

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30 May 2018

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

1 reference

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30 May 2018

Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit

1 reference

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30 May 2018

Acidic and basic fibroblast growth factors stimulate tyrosine kinase activity in vivo.

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30 May 2018

The regulatory role of known tyrosine autophosphorylation sites of the insulin receptor kinase domain. An assessment by replacement with neutral and negatively charged amino acids

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30 May 2018

Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase

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30 May 2018

Involvement of p21ras in Xenopus mesoderm induction

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30 May 2018

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231080

30 May 2018

breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells

1 reference

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30 May 2018

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

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30 May 2018

Two FGF-receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos.

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29 November 2018

Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.

1 reference

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29 November 2018

An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites

1 reference

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29 November 2018

Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin

1 reference

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29 November 2018

A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.

1 reference

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29 November 2018

Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory role of major tyrosine autophosphorylation site of kinase domain of c-Met receptor (scatter factor/hepatocyte growth factor receptor)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The platelet-derived growth factor beta-receptor kinase insert confers specific signaling properties to a chimeric fibroblast growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phosphotyrosine interaction domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of phospholipase C-gamma overexpression on PDGF-induced second messengers and mitogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8622701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.16.3.977

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8622701%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

release_ga6s5r7d2rdn3lwgxl5vntzi5a

1 reference

https://api.fatcat.wiki/v0/release/ga6s5r7d2rdn3lwgxl5vntzi5a

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8622701%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8622701%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

ResearchGate publication ID

0 references

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