hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria (Q24306768)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905258

negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905259

DnaJ heat shock protein family (Hsp40) member A1

1 reference

Parkinsonism associated deglycase

1 reference

activating transcription factor 6

1 reference

BCL2-associated X protein

1 reference

Parkinson disease (autosomal recessive, early onset) 7

1 reference

DNA-damage inducible transcript 3

1 reference

DnaJ heat shock protein family (Hsp40) member A1

1 reference

Cell Death & Differentiation

1 reference

T Gotoh

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K Terada

series ordinal

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S Oyadomari

series ordinal

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M Mori

series ordinal

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language of work or name

English

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publication date

April 2004

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published in

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volume

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issue

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page(s)

390-402

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cites work

Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide

1 reference

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7 January 2021

Nitric oxide: cytotoxicity versus cytoprotection--how, why, when, and where?

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7 January 2021

Nitric oxide and cell signaling pathways in mitochondrial-dependent apoptosis

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7 January 2021

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Induction of CHOP and apoptosis by nitric oxide in p53-deficient microglial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The unfolded protein response: an intracellular signalling pathway with many surprising features

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Organelle-specific initiation of cell death pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The unfolding tale of the unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Identification of novel stress-induced genes downstream of chop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Heat shock proteins: regulators of stress response and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The Hsp70 and Hsp60 chaperone machines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Protein Folding In Vivo: Unraveling Complex Pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Protein folding in the cytosol: chaperonin-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Mechanism of regulation of hsp70 chaperones by DnaJ cochaperones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The J-domain family and the recruitment of chaperone power

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The human DnaJ homologue dj2 facilitates mitochondrial protein import and luciferase refolding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

hsp70-DnaJ chaperone pairs prevent nitric oxide-mediated apoptosis in RAW 264.7 macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Arginase II downregulates nitric oxide (NO) production and prevents NO-mediated apoptosis in murine macrophage-derived RAW 264.7 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

HSDJ, a human homolog of DnaJ, is farnesylated and is involved in protein import into mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Programmed cell death: alive and well in the new millennium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Structure of Bax: coregulation of dimer formation and intracellular localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

1 reference

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Stress management - heat shock protein-70 and the regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Heat shock proteins: endogenous modulators of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Role of the Human Heat Shock Protein hsp70 in Protection against Stress-Induced Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

The chaperone function of hsp70 is required for protection against stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Heat shock protein 70 inhibits apoptosis downstream of cytochrome c release and upstream of caspase-3 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021

Functional analysis of human mitochondrial receptor Tom20 for protein import into mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401369

7 January 2021