Structure of mammalian AMPK and its regulation by ADP (Q24296973)

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Matthew J Sanders

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Elizabeth Underwood

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Richard Heath

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Faith V Mayer

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Chun Jing

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Philip A Walker

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John F Eccleston

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Lesley F Haire

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Peter Saiu

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Steven A Howell

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Stephen R Martin

Structural basis for AMP binding to mammalian AMP-activated protein kinase

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language of work or name

English

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publication date

14 April 2011

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published in

Nature

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volume

472

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issue

7342

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page(s)

230-3

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cites work

1 reference

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

19 March 2017

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Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

19 March 2017

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The regulation of AMP-activated protein kinase by phosphorylation

19 March 2017

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19 March 2017

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A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation

27 September 2017

1 reference

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The CCP4 suite: programs for protein crystallography

19 March 2017

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

19 March 2017

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AMP-activated protein kinase plays a role in the control of food intake

19 March 2017

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The AMP-activated protein kinase cascade--a unifying system for energy control

19 March 2017

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

19 March 2017

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Cytosolic phosphorylation potential

19 March 2017

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The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

19 March 2017

1 reference

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

7 April 2017

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

7 April 2017

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β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

7 April 2017

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The regulation of AMP-activated protein kinase by upstream kinases.

27 September 2017

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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

27 September 2017

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Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

27 September 2017

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

27 September 2017

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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

27 September 2017

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5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.

30 May 2018

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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

30 May 2018

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AMPK structure and regulation from three angles.

30 May 2018

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Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

29 November 2018

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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

29 November 2018

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Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen

29 November 2018

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AMP deamination and purine exchange in human skeletal muscle during and after intense exercise

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21399626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An antibody VH domain with a lox-Cre site integrated into its coding region: bacterial recombination within a single polypeptide chain

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09932

inferred from DOI database lookup

7 January 2021

based on heuristic

AMoRe: an automated package for molecular replacement

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09932

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE09932

1 reference

Dimensions Publication ID

1024797126

0 references

1 reference

1 reference

PubMed publication ID

21399626

1 reference