Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP (Q24296501)

protein tyrosine phosphatase activity

GOA release 2020-03-11

1 reference

Protein tyrosine phosphatase, non-receptor type 2

GOA release 2020-03-11

1 reference

Manuela Klingler-Hoffmann

GOA release 2020-03-11

1 reference

0 references

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Sandra Galic

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Michelle T Fodero-Tavoletti

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Michelle A Puryer

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Tzu-Ching Meng

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Nicholas K Tonks

Molecular and Cellular Biology

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language of work or name

English

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publication date

March 2003

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published in

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volume

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issue

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page(s)

2096-108

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cites work

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PTP1B regulates leptin signal transduction in vivo

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The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

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TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

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Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

19 March 2017

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Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells

19 March 2017

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Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

19 March 2017

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Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

19 March 2017

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

19 March 2017

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Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

19 March 2017

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COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus

19 March 2017

1 reference

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Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains

19 March 2017

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Structural diversity and evolution of human receptor-like protein tyrosine phosphatases

19 March 2017

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Cloning and expression of a widely expressed receptor tyrosine phosphatase

19 March 2017

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Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B

19 March 2017

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Cloning of a cDNA for a major human protein-tyrosine-phosphatase

19 March 2017

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Structure determination of T cell protein-tyrosine phosphatase

19 March 2017

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Crystal structure of human protein tyrosine phosphatase 1B

19 March 2017

1 reference

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Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase

19 March 2017

1 reference

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A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus

19 March 2017

1 reference

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Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance

19 March 2017

1 reference

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The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling

19 March 2017

1 reference

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Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST

19 March 2017

1 reference

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The IRS-signalling system: a network of docking proteins that mediate insulin action

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

19 March 2017

1 reference

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Insulin receptor-associated protein tyrosine phosphatase(s): role in insulin action

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Protein tyrosine phosphatases: dephosphorylating the epidermal growth factor receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Structural and evolutionary relationships among protein tyrosine phosphatase domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Combinatorial control of the specificity of protein tyrosine phosphatases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

The T-cell protein tyrosine phosphatase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

PTP-S2, a nuclear tyrosine phosphatase, is phosphorylated and excluded from condensed chromosomes during mitosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Receptor-like protein-tyrosine phosphatase alpha specifically inhibits insulin-increased prolactin gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Protein tyrosine phosphatases take off.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Differential activities of protein tyrosine phosphatases in intact cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Characterization of the major protein-tyrosine-phosphatases of human placenta.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Purification of the major protein-tyrosine-phosphatases of human placenta

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

The insulin signalling system and the IRS proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149470

Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants

29 November 2018

1 reference

12 December 2020

The juxtamembrane but not the carboxyl-terminal domain of the insulin receptor mediates insulin's metabolic functions in primary adipocytes and cultured hepatoma cells

1 reference

12 December 2020

The Noncatalytic C-terminal Segment of the T Cell Protein Tyrosine Phosphatase Regulates Activity via an Intramolecular Mechanism

1 reference

12 December 2020

Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle

1 reference

12 December 2020