Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses (Q24294677)

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English	Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses	scientific article

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9 January 2020

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses (English)

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9 January 2020

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toll-like receptor

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Toll like receptor 7

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GOA release 2020-03-11

Toll like receptor 9

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GOA release 2020-03-11

Toll like receptor 3

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GOA release 2020-03-11

Toll like receptor 8

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GOA release 2020-03-11

regulation of cytokine production

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GOA release 2020-03-11

Jean-Laurent Casanova

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9 January 2020

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9 January 2020

Capucine Picard

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Sabine Plancoulaine

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9 January 2020

Donald J. Davidson

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Frederic Geissmann

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Emmanuelle Jouanguy

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Armanda Casrouge

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9 January 2020

Celine Eidenschenk

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László Maródi

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Horst von Bernuth

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Abdulaziz Al-Ghonaium

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Kun Yang

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Sami Al-Hajjar

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Chaim Roifman

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Franck J Barrat

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9 January 2020

Robert L Coffman

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9 January 2020

Richard L Miller

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9 January 2020

Xiaoxia Li

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Pierre Lebon

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9 January 2020

Carlos Rodriguez-Gallego

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Helen Chapel

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1 November 2005

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9 January 2020

465-478

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9 January 2020

The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A FADD-dependent innate immune mechanism in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viruses and Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell type-specific involvement of RIG-I in antiviral response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inferences, questions and possibilities in Toll-like receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shigella sonnei Meningitis Due to Interleukin-1 Receptor--Associated Kinase--4 Deficiency: First Association with a Primary Immune Deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Toll-like receptor recognizes bacterial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viruses and interferon: a fight for supremacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferons, interferon-like cytokines, and their receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 Receptor β1 and Toll-Like Receptor 4 Increase IL-1β- and IL-18-Associated Myocarditis and Coxsackievirus Replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of PKR in double-stranded RNA-induced macrophage activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two siblings with lethal pneumococcal meningitis in a family with a mutation in Interleukin-1 receptor-associated kinase 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary immunodeficiency to pneumococcal infection due to a defect in Toll-like receptor signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin receptor-associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate sensing of viruses by toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1R-Associated Kinase 4 Is Required for Lipopolysaccharide- Induced Activation of APC

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Akt kinase activation is important for immunosuppression induced by measles virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of single-stranded RNA viruses by Toll-like receptor 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inherited disorders of human Toll-like receptor signaling: immunological implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human model: a genetic dissection of immunity to infection in natural conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple signaling pathways leading to the activation of interferon regulatory factor 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inborn errors of immunity to infection: the rule rather than the exception

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide-binding protein critically regulates lipopolysaccharide-induced IFN-beta signaling pathway in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does Toll-like receptor 3 play a biological role in virus infections?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16286015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.IMMUNI.2005.09.016

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9 January 2020

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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9 January 2020

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