Jumonji, AT rich interactive domain 2 (Q21981808)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62315

JmjC domain, protein family

1 reference

JmjN domain, protein family

1 reference

Zinc finger, C5HC2-type, protein family

1 reference

ARID DNA-binding domain, protein family

1 reference

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

histone demethylase activity

1 reference

10 September 2018

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

chromatin binding

protein binding

11 references

14 February 2019

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Characterization of zinc finger protein 496 that interacts with Jumonji/Jarid2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jarid2 regulates mouse epidermal stem cell activation and differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Characterization of zinc finger protein 496 that interacts with Jumonji/Jarid2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

DNA binding

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

14 February 2019

JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

transcription factor binding

1 reference

14 February 2019

Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

DNA-binding transcription repressor activity, RNA polymerase II-specific

chromatin binding

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

10 September 2018

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

methylated histone binding

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

histone demethylase activity

histone H3-tri/di/monomethyl-lysine-4 demethylase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

histone methyltransferase complex

cell component

1 reference

21 June 2018

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

ESC/E(Z) complex

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

nucleus

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

21 June 2018

Ensembl genome database project

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

21 June 2018

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

21 June 2018

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

21 June 2018

JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

nucleus

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

histone methyltransferase complex

positive regulation of histone H3-K9 methylation

biological process

1 reference

14 February 2019

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

negative regulation of cell population proliferation

1 reference

14 February 2019

Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

stem cell differentiation

3 references

14 February 2019

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

14 February 2019

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

liver development

1 reference

14 February 2019

Organogenesis of the liver, thymus and spleen is affected in jumonji mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

1 reference

21 June 2018

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

1 reference

14 February 2019

regulation of cell population proliferation

1 reference

14 February 2019

A role of jumonji gene in proliferation but not differentiation of megakaryocyte lineage cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

spleen development

1 reference

14 February 2019

Organogenesis of the liver, thymus and spleen is affected in jumonji mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

negative regulation of transcription by RNA polymerase II

IGI

thymus development

1 reference

14 February 2019

Organogenesis of the liver, thymus and spleen is affected in jumonji mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

negative regulation of histone methylation

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62315&geneProductId=UniProtKB:Q62315

1 reference

21 June 2018

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

1 reference

14 February 2019

negative regulation of transcription, DNA-templated

cellular response to leukemia inhibitory factor

IEP

1 reference

14 February 2019

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

IEP

chromatin organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

1 reference

14 February 2019

histone demethylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

chromatin remodeling

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315

histone H3-K4 demethylation, trimethyl-H3-K4-specific

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62315