Transmembrane serine protease 2 (Q21126599)

peptidase S1A, chymotrypsin family

1 reference

Peptidase S1, PA clan

1 reference

SRCR-like domain superfamily

1 reference

SRCR domain, protein family

1 reference

Serine proteases, trypsin domain, protein family

1 reference

Serine proteases, trypsin family, histidine active site, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A, conserved site, protein family

1 reference

SRCR-like domain, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A repeat, protein family

1 reference

Serine proteases, trypsin family, serine active site, protein family

1 reference

scavenger receptor activity

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

1 reference

9 May 2019

peptidase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

1 reference

9 May 2019

protein binding

IPI

1 reference

9 May 2019

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

IPI

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

1 reference

9 May 2019

serine-type endopeptidase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

1 reference

9 May 2019

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

1 reference

9 May 2019

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

1 reference

9 May 2019

integral component of plasma membrane

TAS

1 reference

9 May 2019

Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

TAS

extracellular exosome

4 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393

26 September 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393

extracellular exosome

3 references

9 May 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

9 May 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

9 May 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

positive regulation of viral entry into host cell

biological process

2 references

9 May 2019

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

9 May 2019

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

protein autoprocessing

IMP

1 reference

26 September 2017

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393

receptor-mediated endocytosis

IMP

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

9 May 2019

Ensembl genome database project

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

9 May 2019

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

9 May 2019

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

protein autoprocessing

vesicle-mediated transport

IBA

IMP

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

endocytosis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393

Low-density lipoprotein (LDL) receptor class A, conserved site

has part(s)

1 reference

serine proteases, trypsin family, histidine active site

1 reference

serine proteases, trypsin domain

1 reference

low-density lipoprotein (LDL) receptor class A repeat

1 reference

SRCR-like domain

1 reference

SRCR domain

1 reference

Serine proteases, trypsin family, serine active site

1 reference

Guide to Pharmacology Target ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

2421

1 reference

https://www.guidetopharmacology.org/coronavirus.jsp