NADH:ubiquinone oxidoreductase subunit A6 (Q21123058)

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mammalian protein found in Homo sapiens

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
CI-B14
Complex I-B14
LYR motif-containing protein 6
NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 6
NADH-ubiquinone oxidoreductase B14 subunit
NDUFA6

Language	Label	Description	Also known as
English	NADH:ubiquinone oxidoreductase subunit A6	mammalian protein found in Homo sapiens	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 CI-B14 Complex I-B14 LYR motif-containing protein 6 NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 6 NADH-ubiquinone oxidoreductase B14 subunit NDUFA6

Statements

1 reference

13 November 2019

UniProt protein ID

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P56556

Complex 1 LYR protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P56556

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

NADH dehydrogenase (ubiquinone) activity

determination method or standard

mitochondrial respiratory chain complex I

determination method or standard

4 references

7 November 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

7 November 2018

Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

7 November 2018

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

7 November 2018

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

mitochondrial membranes

determination method or standard

1 reference

8 April 2019

Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

mitochondrial respiratory chain complex I

determination method or standard

5 references

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

8 April 2019

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

8 April 2019

Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

8 April 2019

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56556

determination method or standard

biological process

response to oxidative stress

determination method or standard

1 reference

7 November 2018

Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

mitochondrial respiratory chain complex I assembly

determination method or standard

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

mitochondrial electron transport, NADH to ubiquinone

determination method or standard

1 reference

1 January 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56556&geneProductId=UniProtKB:P56556

determination method or standard

response to oxidative stress

determination method or standard

physically interacts with

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1703

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000418842

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418842

ENSP00000475402

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475402

ENSP00000475816

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475816

ENSP00000482543

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482543

ENSP00000484723

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484723

ENSP00000485713

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485713

ENSP00000487431

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487431

ENSP00000486423

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486423

ENSP00000485886

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485886

ENSP00000473478

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473478

ENSP00000485795

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485795

ENSP00000485080

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485080

ENSP00000487462

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487462

ENSP00000486781

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486781

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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