TEK receptor tyrosine kinase (Q21097266)

Immunoglobulin-like fold

1 reference

Protein kinase-like domain superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

Fibronectin type III, protein family

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, receptor Tie-2, Ig-like domain 1, N-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

EGF-like domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

protein binding

7 references

8 April 2019

VE-PTP controls blood vessel development by balancing Tie-2 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Effects of angiopoietins-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Large-scale structural analysis of the classical human protein tyrosine phosphatome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

transmembrane receptor protein tyrosine kinase activity

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

24 April 2018

protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

8 April 2019

Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: enzymatic characterization of Tie2 and phospho-Tie2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

signaling receptor activity

1 reference

8 April 2019

Characterization and expression of a novel alternatively spliced human angiopoietin-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

growth factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

receptor tyrosine kinase

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

transmembrane signaling receptor activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

transmembrane receptor protein tyrosine kinase activity

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

cell-cell junction

1 reference

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

focal adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

integral component of plasma membrane

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

24 April 2018

24 April 2018

Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

stress fiber

1 reference

8 April 2019

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

microvillus

1 reference

8 April 2019

Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

cell surface

1 reference

8 April 2019

Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

basal plasma membrane

1 reference

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

basolateral plasma membrane

1 reference

8 April 2019

Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

apical plasma membrane

1 reference

8 April 2019

Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

actin filament

1 reference

8 April 2019

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

membrane raft

1 reference

8 April 2019

Lipid rafts serve as signaling platforms for Tie2 receptor tyrosine kinase in vascular endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

plasma membrane

integral component of plasma membrane

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

8 April 2019

Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

receptor complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

negative regulation of endothelial cell apoptotic process

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

positive regulation of protein kinase B signaling

positive regulation of protein phosphorylation

response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

heart trabecula formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

transmembrane receptor protein tyrosine kinase signaling pathway

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

10 September 2018

Biological characterization of angiopoietin-3 and angiopoietin-4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

regulation of endothelial cell apoptotic process

1 reference

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

cell-cell signaling

1 reference

8 April 2019

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

response to peptide hormone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

sprouting angiogenesis

1 reference

8 April 2019

Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

negative regulation of apoptotic process

1 reference

8 April 2019

Tie2: a journey from normal angiogenesis to cancer and beyond

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

endochondral ossification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of intracellular signal transduction

1 reference

8 April 2019

Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

response to organic substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of angiogenesis

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Biological characterization of angiopoietin-3 and angiopoietin-4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

MAPK cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

positive regulation of phosphatidylinositol 3-kinase activity

positive regulation of endothelial cell migration

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Biological characterization of angiopoietin-3 and angiopoietin-4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

response to estrogen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

regulation of vascular permeability

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

protein complex oligomerization

1 reference

8 April 2019

Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

endothelial cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

1 reference

10 September 2018

positive regulation of ERK1 and ERK2 cascade

negative regulation of angiogenesis

1 reference

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

protein autophosphorylation

1 reference

8 April 2019

Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: enzymatic characterization of Tie2 and phospho-Tie2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of focal adhesion assembly

1 reference

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

regulation of establishment or maintenance of cell polarity

1 reference

8 April 2019

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of phosphatidylinositol 3-kinase signaling

3 references

10 September 2018

Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: enzymatic characterization of Tie2 and phospho-Tie2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

substrate adhesion-dependent cell spreading

1 reference

8 April 2019

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

response to cAMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

definitive hemopoiesis

1 reference

8 April 2019

Tie2: a journey from normal angiogenesis to cancer and beyond

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of actin cytoskeleton reorganization

1 reference

8 April 2019

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

negative regulation of inflammatory response

1 reference

8 April 2019

Tie2: a journey from normal angiogenesis to cancer and beyond

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

leukocyte migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

1 reference

8 April 2019

signal transduction

1 reference

8 April 2019

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

negative regulation of signal transduction

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

cell differentiation

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

negative regulation of apoptotic process

positive regulation of ERK1 and ERK2 cascade

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Lipid rafts serve as signaling platforms for Tie2 receptor tyrosine kinase in vascular endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02763&geneProductId=UniProtKB:Q02763

angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

transmembrane receptor protein tyrosine kinase signaling pathway

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

8 April 2019

Biological characterization of angiopoietin-3 and angiopoietin-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of endothelial cell migration

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Biological characterization of angiopoietin-3 and angiopoietin-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of phosphatidylinositol 3-kinase signaling

Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of angiogenesis

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Biological characterization of angiopoietin-3 and angiopoietin-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

positive regulation of protein kinase B signaling

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Lipid rafts serve as signaling platforms for Tie2 receptor tyrosine kinase in vascular endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02763

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5657

English

tyrosine-protein kinase, active site

17 August 2016

has part(s)

1 reference

fibronectin type III

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

immunoglobulin-like domain

1 reference

EGF-like, conserved site

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Tyrosine-protein kinase, receptor Tie-2, Ig-like domain 1, N-terminal

1 reference

EGF-like domain

1 reference

D08.811.913.696.620.682.725.400.925.500

Identifiers

MeSH descriptor ID

D042787

subject named as

Receptor, TIE-2

0 references

MeSH tree code

0 references

D12.776.476.568.400.925.500

0 references

D12.776.543.750.630.687.500

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023