IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo (Q84101581)

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scientific article published on 01 July 2009

Language	Label	Description	Also known as
English	IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo	scientific article published on 01 July 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19544494%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19544494%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Burkhard Becher

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19544494%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Gabor Gyülvészi

1

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Europe PubMed Central

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1 February 2020

Stefan Haak

2

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Europe PubMed Central

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1 February 2020

publication date

1 July 2009

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1 February 2020

European Journal of Immunology

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1 February 2020

39

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1 February 2020

7

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1 February 2020

1864-1869

1 reference

Europe PubMed Central

PubMed publication ID

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1 February 2020

How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

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APC-derived cytokines and T cell polarization in autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

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Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Transforming growth factor-beta induces development of the T(H)17 lineage

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-23 promotes maintenance but not commitment to the Th17 lineage

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939305

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EJI.200939305

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19544494%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19544494%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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