Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. (Q41731870)

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scientific article published on March 2000

Language	Label	Description	Also known as
English	Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.	scientific article published on March 2000

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. (English)

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Europe PubMed Central

PubMed publication ID

8 October 2017

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author name string

Ollmann M

1

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8 October 2017

Young LM

2

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8 October 2017

Di Como CJ

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8 October 2017

Karim F

4

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8 October 2017

Belvin M

5

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8 October 2017

Robertson S

6

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8 October 2017

Whittaker K

7

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8 October 2017

Demsky M

8

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8 October 2017

Fisher WW

9

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8 October 2017

Buchman A

10

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8 October 2017

Duyk G

11

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8 October 2017

Friedman L

12

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8 October 2017

Prives C

13

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8 October 2017

Kopczynski C

14

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8 October 2017

language of work or name

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publication date

1 March 2000

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Europe PubMed Central

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8 October 2017

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Europe PubMed Central

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8 October 2017

101

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Europe PubMed Central

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8 October 2017

1

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Europe PubMed Central

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8 October 2017

91-101

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Europe PubMed Central

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8 October 2017

An emerging blueprint for apoptosis in Drosophila

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

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7 January 2021

based on heuristic

inferred from DOI database lookup

Basic local alignment search tool

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7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of mutant p53 in clam leukemia cells.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of the tumor suppressor p53 in spermatogenesis

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7 January 2021

based on heuristic

inferred from DOI database lookup

p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Drosophila p53 binds a damage response element at the reaper locus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of cell cycle regulatory proteins (p53, pRb) in the human female genital tract

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Uncoupling cell fate determination from patterned cell division in the Drosophila eye.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental control of cell cycle regulators: a fly's perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle checkpoints: preventing an identity crisis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

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Tumor suppressors: a developing role for p53?

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7 January 2021

based on heuristic

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The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the specific DNA binding function of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The p53 gene family

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Life (and death) in a malignant tumour

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Solution structure of the tetrameric minimum transforming domain of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Exploring the limits of nearest neighbour secondary structure prediction.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Atm is dispensable for p53 apoptosis and tumor suppression triggered by cell cycle dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer therapy and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Facing death in the fly: genetic analysis of apoptosis in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 and ATM: cell cycle, cell death, and cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of the Rb/E2F pathway in cell growth control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A teratologic suppressor role for p53 in benzo(a)pyrene–treated transgenic p53-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent apoptosis suppresses radiation-induced teratogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Baculovirus p33 binds human p53 and enhances p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncogenes and tumour suppressor genes in first trimester human fetal gonadal development.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel protein with strong homology to the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The cell cycle program in germ cells of the Drosophila embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell fate in the Drosophila ommatidium

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 function and dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ectopic expression of human p53 inhibits entry into S phase and induces apoptosis in the Drosophila eye imaginal disc.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-mediated germ cell quality control in spermatogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980626-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0092-8674(00)80626-1

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

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