PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. (Q40738816)

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scientific article published on March 2002

Language	Label	Description	Also known as
English	PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.	scientific article published on March 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

phosphorylation

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

author name string

Lucy C Coles

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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publication date

1 March 2002

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

21

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

14

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

2236-2244

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Regulation of Raf-1 activation and signalling by dephosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Mechanism of inhibition of Raf-1 by protein kinase A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Paradoxical activation of Raf by a novel Raf inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Mitogen-activated protein (MAP) kinase phosphorylation of MAP kinase kinase: determination of phosphorylation sites by mass spectrometry and site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Negative regulation of Raf-1 by phosphorylation of serine 621.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

The complexity of Raf-1 regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Identification of residues in the cysteine-rich domain of Raf-1 that control Ras binding and Raf-1 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

21 January 2018

Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205302

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1205302

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11948406%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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