Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT (Q36371501)

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English	Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT	scientific article

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scholarly article

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21 December 2019

Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT (English)

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21 December 2019

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21 December 2019

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Shigeharu Myou

1

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21 December 2019

Alan R Leff

2

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21 December 2019

Saori Myo

3

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21 December 2019

Evan Boetticher

4

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21 December 2019

Jiankun Tong

5

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21 December 2019

Angelo Y Meliton

6

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21 December 2019

Jie Liu

7

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21 December 2019

Nilda M Munoz

8

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21 December 2019

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1 November 2003

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21 December 2019

Journal of Experimental Medicine

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21 December 2019

198

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21 December 2019

10

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21 December 2019

1573-1582

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21 December 2019

Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

In vivo and in vitro effects of SAR 943, a rapamycin analogue, on airway inflammation and remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

In vivo protein transduction: delivery of a biologically active protein into the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin 5: the role of specific adhesion molecules and phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperreactivity in sensitized guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

PI 3-kinase: structural and functional analysis of intersubunit interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Immunological aspects of allergic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

30 September 2017

In vivo priming of FcalphaR functioning on eosinophils of allergic asthmatics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

28 June 2018

Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

28 June 2018

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

28 June 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

28 June 2018

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

28 June 2018

IL-5-induced integrin adhesion of human eosinophils caused by ERK1/2-mediated activation of cPLA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

Blockade of focal clustering and active conformation in beta 2-integrin-mediated adhesion of eosinophils to intercellular adhesion molecule-1 caused by transduction of HIV TAT-dominant negative Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

Effect of wortmannin on human eosinophil responses in vitro and on bronchial inflammation and airway hyperresponsiveness in Guinea pigs in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

p110beta and p110delta phosphatidylinositol 3-kinases up-regulate Fc(epsilon)RI-activated Ca2+ influx by enhancing inositol 1,4,5-trisphosphate production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

Expression and activation of protein kinase C-zeta in eosinophils after allergen challenge.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194122

21 September 2018

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Il-13 and IFN-gamma: interactions in lung inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contraction of human bronchial smooth muscle caused by activated human eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of an antibody to interleukin-5 in a monkey model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of smooth muscle contraction elicited by cationic proteins in guinea pig trachealis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular protein kinase C activity in asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling in neuropeptide-induced migration of human eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchoconstrictor effects of leukotriene C in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchial responsiveness among inbred mouse strains. Role of airway smooth-muscle shortening velocity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20030298

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623911%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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