The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity (Q33502223)

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English	The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 July 2017

The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity (English)

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Europe PubMed Central

PubMed publication ID

27 July 2017

H. Leighton Grimes

5

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H Leighton Grimes

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Europe PubMed Central

PubMed publication ID

27 July 2017

author name string

Paritha I Arumugam

1

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Europe PubMed Central

PubMed publication ID

27 July 2017

Fabrizia Urbinati

2

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Europe PubMed Central

PubMed publication ID

27 July 2017

Chinavenmeni S Velu

3

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Europe PubMed Central

PubMed publication ID

27 July 2017

Tomoyasu Higashimoto

4

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Europe PubMed Central

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27 July 2017

Punam Malik

6

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Europe PubMed Central

PubMed publication ID

27 July 2017

language of work or name

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publication date

10 September 2009

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Europe PubMed Central

PubMed publication ID

27 July 2017

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Europe PubMed Central

PubMed publication ID

27 July 2017

4

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Europe PubMed Central

PubMed publication ID

27 July 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

e6995

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

copyright license

Creative Commons Attribution 4.0 International

10 September 2009

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April 2022 Public Data File from Crossref

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1 reference

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Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.

1 reference

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1 reference

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Cohesins functionally associate with CTCF on mammalian chromosome arms

1 reference

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Cohesin mediates transcriptional insulation by CCCTC-binding factor

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1 reference

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Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effects

1 reference

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21 June 2018

Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

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Suppression of clonal dominance in cultured human lymphoid cells by addition of the cHS4 insulator to a lentiviral vector

1 reference

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21 June 2018

Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences

1 reference

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21 June 2018

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

21 June 2018

Antagonistic regulation of beta-globin gene expression by helix-loop-helix proteins USF and TFII-I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

21 June 2018

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

1 reference

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21 June 2018

CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

1 reference

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21 June 2018

Chromatin boundaries and chromatin domains.

1 reference

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21 June 2018

Self-inactivating retroviral vectors with improved RNA processing.

1 reference

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The 5'-HS4 chicken beta-globin insulator is a CTCF-dependent nuclear matrix-associated element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

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Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

21 June 2018

CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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Retrovirus silencer blocking by the cHS4 insulator is CTCF independent

1 reference

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Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells

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Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots

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Development of virus vectors for gene therapy of beta chain hemoglobinopathies: flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo

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The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation

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Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities

1 reference

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Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

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Insulators and boundaries: versatile regulatory elements in the eukaryotic genome

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Structural and functional conservation at the boundaries of the chicken beta-globin domain

1 reference

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Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta-globin in engrafted mice.

1 reference

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

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The cHS4 insulator increases the probability of retroviral expression at random chromosomal integration sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

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The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

1 reference

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The establishment of active chromatin domains

1 reference

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Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells

1 reference

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1 reference

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21 June 2018

Development of a self-inactivating lentivirus vector.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

21 June 2018

Stem cell gene therapy, position effects and chromatin insulators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

21 June 2018

Characterization of the chicken beta-globin insulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

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1 reference

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1 reference

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1 reference

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Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

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Recruitment of histone modifications by USF proteins at a vertebrate barrier element

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

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Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

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High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

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Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

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Effect of deletion and the site of insertion in double copy anti-tat retroviral vectors: viral titres and production of anti-tat mRNA.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

21 January 2018

Topological constraints governing the use of the chicken HS4 chromatin insulator in oncoretrovirus vectors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

21 January 2018

A chromatin insulator determines the nuclear localization of DNA.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

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Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

21 January 2018

Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

21 January 2018

The role of CTCF in regulating nuclear organization

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006995

21 January 2018

Self-inactivating lentiviral vectors resist proviral methylation but do not confer position-independent expression in hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736623

31 October 2018

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10.1371/JOURNAL.PONE.0006995

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

2009PLoSO...4.6995A

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

ResearchGate publication ID

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