Genomic instability in mice lacking histone H2AX (Q28589826)

31 January 2017

title

Genomic instability in mice lacking histone H2AX (English)

1 reference

31 January 2017

main subject

H2A.X variant histone

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MutL homolog 1

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Breast cancer 1, early onset

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Transformation related protein 53 binding protein 1

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Nibrin

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Proliferating cell nuclear antigen

1 reference

Óscar Fernández-Capetillo

Vincenzo Coppola

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object named as

Oscar Fernandez-Capetillo

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Michel C. Nussenzweig

object named as

Michel C. Nussenzweig

1 reference

Bernardo Reina San-Martin

31 January 2017

object named as

Bernardo Reina-San-Martin

1 reference

31 January 2017

Lino Tessarollo

1 reference

31 January 2017

Arkady Celeste

1 reference

31 January 2017

Simone Petersen

1 reference

31 January 2017

Peter J. Romanienko

1 reference

31 January 2017

Hua Tang Chen

1 reference

31 January 2017

Olga A. Sedelnikova

1 reference

31 January 2017

Eric Meffre

1 reference

31 January 2017

Michael J. Difilippantonio

1 reference

31 January 2017

Christophe Redon

1 reference

31 January 2017

Duane R. Pilch

1 reference

31 January 2017

Alexandru Olaru

1 reference

31 January 2017

Michael Eckhaus

1 reference

31 January 2017

R. Daniel Camerini-Otero

1 reference

31 January 2017

Ferenc Livak

1 reference

31 January 2017

Katia Manova

1 reference

31 January 2017

William M. Bonner

1 reference

31 January 2017

André Nussenzweig

1 reference

31 January 2017

language of work or name

English

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publication date

3 May 2002

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31 January 2017

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31 January 2017

volume

296

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31 January 2017

issue

5569

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31 January 2017

page(s)

922–927

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Histone H2A variants H2AX and H2AZ

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Chromosomal stability and the DNA double-stranded break connection

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Megabase chromatin domains involved in DNA double-strand breaks in vivo

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Recombinational DNA double-strand breaks in mice precede synapsis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Atm-deficient mice: a paradigm of ataxia telangiectasia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Homologous and non-homologous recombination differentially affect DNA damage repair in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Ku80 is required for immunoglobulin isotype switching

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721576

Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/11934988

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1069398

1 reference

1 reference

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1 reference