Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796 (Q27486816)

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scientific article (publication date: September 2008)

Language	Label	Description	Also known as
English	Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796	scientific article (publication date: September 2008)

Statements

scholarly article

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Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796 (English)

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Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Anita Y M Howe

1

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Huiming Cheng

2

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Stephen Johann

3

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Stanley Mullen

4

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Srinivas K Chunduru

5

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Dorothy C Young

6

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Joel Bard

7

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Rajiv Chopra

8

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Girija Krishnamurthy

9

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Tarek Mansour

10

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John O'Connell

11

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language of work or name

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publication date

September 2008

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Antimicrobial Agents and Chemotherapy

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52

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9

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3327-38

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Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase

1 reference

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Evolution of Resistant M414T Mutants among Hepatitis C Virus Replicon Cells Treated with Polymerase Inhibitor A-782759

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Molecular Mechanism of a Thumb Domain Hepatitis C Virus Nonnucleoside RNA-Dependent RNA Polymerase Inhibitor

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20 March 2017

SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells

1 reference

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Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

1 reference

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20 March 2017

Robust hepatitis C virus infection in vitro

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20 March 2017

Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor

1 reference

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20 March 2017

Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

1 reference

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20 March 2017

Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation

1 reference

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20 March 2017

Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

1 reference

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Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons

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20 March 2017

Nucleotide and amino acid complexity of hepatitis C virus quasispecies in serum and liver

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

1 reference

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20 March 2017

Complete replication of hepatitis C virus in cell culture

1 reference

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Efficient initiation of HCV RNA replication in cell culture

1 reference

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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

1 reference

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7 April 2017

Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium

1 reference

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7 April 2017

Nucleotide sequence and mutation rate of the H strain of hepatitis C virus

1 reference

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Valopicitabine dihydrochloride:a specific polymerase inhibitor of hepatitis C virus.

1 reference

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29 September 2017

Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.

1 reference

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Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations

1 reference

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Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase

1 reference

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Characterization of the inhibition of hepatitis C virus RNA replication by nonnucleosides.

1 reference

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Global burden of disease (GBD) for hepatitis C.

1 reference

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1 reference

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Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs

1 reference

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HCV RNA-dependent RNA polymerase as a target for antiviral development

1 reference

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1 reference

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Clinical significance of hepatitis C virus genotypes and quasispecies.

1 reference

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Ribavirin suppresses replication of lymphadenopathy-associated virus in cultures of human adult T lymphocytes

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Hepatitis C virus genotypes and quasispecies

1 reference

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27 November 2018

Identifiers

10.1128/AAC.00238-08

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