The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site (Q24629670)

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Language	Label	Description	Also known as
English	The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site	scientific article

Statements

scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8710867%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8710867%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

solution structure

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based on heuristic

inferred from title

1

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17 October 2019

author name string

J W Carpenter

2

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17 October 2019

S Zhong

3

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17 October 2019

S Ghosh

4

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17 October 2019

R M Bell

5

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17 October 2019

S L Campbell

6

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17 October 2019

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1 August 1996

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17 October 2019

Proceedings of the National Academy of Sciences of the United States of America

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17 October 2019

93

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17 October 2019

16

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17 October 2019

8312-8317

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PMC publication ID

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17 October 2019

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Interaction of the protein kinase Raf-1 with 14-3-3 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Activation of Raf-1 by 14-3-3 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Purification, cDNA-cloning and expression of human diacylglycerol kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

The ins and outs of Raf kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Two distinct Raf domains mediate interaction with Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Protein kinase C: structure, function, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Improved spectral resolution in cosy 1H NMR spectra of proteins via double quantum filtering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

7 April 2017

Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Tautomeric states of the active-site histidines of phosphorylated and unphosphorylated IIIGlc, a signal-transducing protein from Escherichia coli, using two-dimensional heteronuclear NMR techniques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Raf meets Ras: completing the framework of a signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Residues in the Second Cysteine-rich Region of Protein Kinase C δ Relevant to Phorbol Ester Binding as Revealed by Site-directed Mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Mutational activation of c-raf-1 and definition of the minimal transforming sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Mechanism of activation of the vav protooncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Lipid activation of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

The N-terminal region of n-Chimaerin allows lipid modulation of the C-terminal p21rac-GTPase activating domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

27 September 2017

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

30 May 2018

Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.

1 reference

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30 May 2018

Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

30 May 2018

Identification of a transforming activity suppressing sequence in the c-raf oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

30 May 2018

The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

30 May 2018

Precise vicinal coupling constants 3JHN alpha in proteins from nonlinear fits of J-modulated [15N,1H]-COSY experiments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38667

30 May 2018

Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: applicati

1 reference

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19 June 2018

Solution structure of a cysteine rich domain of rat protein kinase C

1 reference

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28 November 2018

Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the 14.3.3 zeta domains important for self-association and Raf binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/8710867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear magnetic resonance investigation of 15N-labeled histidine in aqueous solution

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EXAFS study of the zinc-binding sites in the protein transcription factor IIIA

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete resonance assignment for the polypeptide backbone of interleukin 1.beta. using three-dimensional heteronuclear NMR spectroscopy

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.93.16.8312

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8710867%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1996PNAS...93.8312M

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8710867%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

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17 October 2019

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