VITAMIN A DEFICIENCY
DISORDER(VADD)
Dr. Jafer M(GP)
Dietary sources of retinol
Animal foods
• liver is the best source
• Milk products are also very rich
Plant foods
• important for poor people,
carrots,mangoes,papaya, rice etc
Function of vitamin A
• Maintenance of healthy epithelium
• Formation of visual purple
Clinical signs and symptoms
• XN – night blindness
- poor dark adaptation
- earliest symptom
• X1A –conjunctival xerosis (reversible with PX)
• X1 B – bitot’s spot
• X2 - corneal xerosis
• X3A – corneal ulceration with xerosis
• X3B - keratomalacia (liquefaction of part of the cornea)
• XS - Xerophthalmia scar
• XF – Xerophthalmia fundus – pale yellow spot near the course
of retinal vessels
Treatment indications
• All children with signs of xerophthalmia
• Measles
• PEM
• Diarrhea
• Recommended dosage
for age > 1yr or wt > 8kg = 200,000 IU immediately, the
following days and four weeks later
• Preventive px
• under one yr = 100, 000 IU (at 6 months )
• Lactating mothers 200,000 IU vitamin A P.O. at delivery
or during the next 2 months
• for age > 1yr or wt > 8kg = 200,000 IU every 3-4 months
Prevention ….
• Distribution of massive dose capsule
• Fortification
• Horticulture
• HE
• Immunization esp measles