Vitamin A Deficiency - Quick Chart Summary
Vitamin Type:           Fat-soluble vitamin (Retinol)
Functions:              Vision, immunity, epithelial integrity, growth
Causes:                 Poor diet, malabsorption, infections, increased needs
Clinical Features (WHO Xerophthalmia Classification):
XN:                     Night blindness - Early symptom
X1A:                    Conjunctival xerosis - Dry conjunctiva
X1B:                    Bitot's spots - Foamy, white patches on conjunctiva
X2:                     Corneal xerosis - Dry cornea
X3A:                    Corneal ulceration (<1/3) - Small ulcer
X3B:                    Corneal ulceration (>1/3) - Large ulcer or keratomalacia
XS:                     Corneal scar - From healed ulcer
XF:                     Xerophthalmic fundus - Rare, advanced stage
Systemic Signs:         Growth retardation, recurrent infections, rough/dry skin
Diagnosis:              Clinical signs, serum retinol < 0.70 µmol/L, impression cytology
Prevention:
Dietary intake:         Green leafy veg, carrots, papaya, liver, eggs
Supplementation:        6-11 months: 100,000 IU
                        12-59 months: 200,000 IU every 6 months
Fortification:          Milk, oil, sugar with vitamin A
Health Education:       Mothers, school programs, ASHA/AWW workers
Treatment (WHO Guidelines):
< 6 months:             50,000 IU - Day 1, Day 2, Day 14
6-12 months:            100,000 IU - Same as above
> 12 months:            200,000 IU - Same as above