VIRUSES
Curriculum of cambridge
international examinations
( igcse ) – ktsp
INTRODUCTION,
CHARATERISTIC AND
REPRODUCTION OF VIRUS
BY :
1.IRENA LUCY
2.GITA YULIA SARI
3.HENDI AVIANO P
4.SAMUEL PIRDION
LEARNING OUTCOME
MATERIAL
INTRODUCTION
qVirus is the latin word for toxin.
qVirus history began when a man named A.Mayer, a
German scientist, discovered one in 1883. His
research was on the cause of Tobacco mosaic
disease.
qMayer’s hypotesis was tasted by a Russian scientist
named Dmitri Iwanowski in 1892.
qSix years later, a Dutch scientist named Martinus W.
Beijerinck did the experiment the same as what
Iwanowski’s had done.
qViirology is the study of viruses.
A. MAYER RESEARCH
Tobacco mosaic disease hindered the growth of tobacco plant (dwa
Mayer conclude that “The disease was caused by a very small bacterium w
DMITRI IWANOWSKI RESEARCH
eaf extract in a way that wouldn’t allow bacteria to pass through and obtained the tobacc
He conclude that “ a bacterium was the caused
MARTINUS W. BEIJERINCK
Beijerinck postulated the presence of an agent that
infected the tobacco plant, although he didn’t know
what it was.
He called the infected agent as filterable virus
because it couldn’t pass through the bacterium filter
and couldn’t be observed with microscope.
The term filterable virus was shortened into Virus.
Iwanowski and Beijerinck were considered the
discoverers of Virus.
A. VIRUS CHARATERISTIC
1. SIZE
Viruses are very small. They are between 25-300 nm
(1nm = 10-9 ).
The smallest known virus is poliovirus, it is only 25 nm
in length.
Bacteriophages and Tobacco Mosai Virus (TMV) are
among the largest virusses known with 100 nm and
300 nm in length,respectively.
Virus can only be observed through an electron
microscope since 1930.
Viruses are infectious agents with both living and nonliving
characteristics.
1. Living characteristics of viruses
a. They reproduce at a fantastic rate, but only in
living host cells.
b. They can mutate.
2. Nonliving characteristics of viruses
a. They are acellular, that is, they contain no
cytoplasm or cellular organelles.
b. They carry out no metabolism on their
own and must replicate using the host cell's
metabolic machinery. In other words, viruses
don't
grow and divide. Instead, new viral components
are synthesized and assembled within the
infected host cell.
c. The vast majority of viruses possess either DNA
or
RNA but not both.
THE SIZE
Viruses are usually much smaller than bacteria and are submicrosco
ze from 5 to 300 nanometers (nm) , although some Paramyxoviruses can be up to 14,000n
Hepatitis B virus
2. SHAPE
Viruses have various shapes.
1. Sphere
Influenza viruses
AIDS-causing viruses (HIV) are shperes.
AIDS-causing viruses/ HIV
2. Rod- shaped
An example of rod- shaped virus is The Tobacc
Tobacco Mosaic Virus
mbers of the family Solanaceae. The infection causes characteristic patterns (mottling and
Schematic model of TMV:
1. nucleic acid (RNA)
2. capsomer (protomer)
3. capsid (a capsid is the protein shell of a virus.)
3. T- shaped
An example of T- shaped virus is the one infecting bacteria (Bacteriopha
Oval- shaped
The rabies virus is oval-shaped virus.
3. STRUCTURE AND FUNCTION
Virus is not a cell (Acellular).
A virus contains a particle called Virion, which
cancrystallized and shows a mineral
characteristics rather than life.
Virus is composed of a nucleic acid and protein
coat called a capsid.
1. Nucleic acid
vNucleic acid are moleculthat carry
genetic information.
vA virus has only one type of nucleic acid
i.e. DNA (Deoxyribonucleic acid )or
RNA (Ribonuclei acid).
2. Protein envelope (capsid)
vThe protein coat covering the genetic
material is called the capsid,
composed of a large number protein
subunits called capsomers.
vThe capsid giving the virus its shape.
CAPSID / CAPSOMERS
Helical Structure
Helical structure such as Tobacco M
Rod shape
Polyhedral
Capsomer
Polyhedral such as Adenovirus.
Complex shape
Capsid
Nucleic acid and capsid from a structure called
Nucleocapsid.
In some viruses, the nucleocapsid has a membrane called
envelope.
It is composed of lipids and proteins and helps the virus
to infect cells.
An example of a virus with an envelope is the
Influenzavirus.
Viruses without an envelope are called Naked Viruses.
B. REPRODUCTION OF VIRUS
There’re 5 steps in virus reproduction :
1.Attachment
2.Penetration
3.Replication and synthesis
4.Maturation
5.Lysis