Thyroid Gland Anatomy
Thyroid Gland Anatomy
Thyroid Gland Anatomy
Anatomy
THYROID GLAND
Endocrine gland, situated in the
lower part of the front and sides of
the neck.
Extends : from oblique line of thyroid
cartilage to the 5th or 6th tracheal
ring.
Lie against C5,C6,C7 & T1.
Consist Right & Left lobes, joined by
isthmus.
A 3rd pyramidal lobe may project
upwards from the isthmus.
Capsules: two; True & false.
Larger in females than males.
Development: from the endoderm of
the floor of primitive oral cavity in the
region of the future foramen caecum
and ultimobranchial body.
RELATIONS OF THE LOBES
The lobes are conical in
shape having:
An apex
A base
Three surfaces: Lateral,
medial, posterolateral
Two borders: Anterior and
posterior
Apex:
directed upwards and slightly
laterally.
Lymphatic drainage:
Upper & lower deep cervical
lymph node
Pretracheal and paratracheal
lymph node
Nerve supply:
Middle cervical ganglion
Superior and inferior cervical
ganglia
HISTOLOGY
2 types of cells :
follicular & parafollicular.
The follicular cells secrete T3 & T4.
T3 & T4 binds with glycoproteins
to form the thyroglobulin (colloid).
Most of the thyroid follicles are full
of stored Thyroglobulin (colloid).
Parafollicular cells/clear (C) cells
are found among the follicular
cells.
They pale staining cells with a
granular cytoplasm.
Unlike follicular cells, they are not
exposed to the follicular lumen.
They secrete Calcitonin which help
regulating blood calcium levels.
Follicular cells
Follicular cells