Cambridge International Examinations
Cambridge International General Certificate of Secondary Education
               BIOLOGY                                                                                                                                      0610/21
               Paper 2 Multiple Choice (Extended)                                                                               October/November 2017
                                                                                                                                                     45 minutes
               Additional Materials:           Multiple Choice Answer Sheet
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               There are forty questions on this paper. Answer all questions. For each question there are four possible
               answers A, B, C and D.
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                        The syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate.
                                            This document consists of 15 printed pages and 1 blank page.
               IB17 11_0610_21/4RP
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1   Which term is defined as all the chemical reactions that occur in cells?
    A    photosynthesis
    B    protein synthesis
    C    respiration
    D    metabolism
2   The diagram shows a section of DNA from a chimpanzee.
               A   G   C       T     A   C   A    G      A    G
    Which diagram shows a section of DNA from the organism that is most closely related to the
    chimpanzee?
    A          A   G   C       T     A   C   A    G      A    T
    B          A   G   C       T     A   C   A    G      T    T
    C          A   T   C       A     A   C   A    G      T    T
    D          A   T   C       T     A   C   A    G      T    T
3   The length of a mitochondrion in a photomicrograph is 15 mm.
    The actual length of the mitochondrion is 3 µm.
    What is the magnification of the photomicrograph?
    A    ×5                B   ×45           C    ×5000           D    ×45 000
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4   The diagrams show a leaf and its internal structure.
    What are the levels of organisation of the labelled structures?
                    1               2                       3
      A            cell           tissue         organ system
      B           organ            cell                tissue
      C        organ system       tissue                   cell
      D           tissue           cell                organ
5   Different factors affect the rate of diffusion of molecules across a membrane.
    Which row represents changes to factors that will increase the rate of diffusion?
                concentration
                                    thickness              surface area
               gradient across                                            temperature
                                  of membrane              of membrane
                a membrane
      A           decrease          decrease                 increase      increase
      B           decrease          increase                 increase      decrease
      C           increase          decrease                 increase      increase
      D           increase          increase                 decrease      decrease
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6   A red blood cell and a palisade mesophyll cell are placed in a solution which has a higher water
    potential than the cells.
    What will happen to each cell?
                                    palisade
               red blood cell
                                  mesophyll cell
      A           bursts                  bursts
      B           bursts              gains mass
      C         loses mass            gains mass
      D         loses mass            loses mass
7   The diagram shows a protease molecule catalysing the break down of a protein molecule.
    What are the parts labelled P, Q, R and S?
               enzyme           product            substrate       active site
      A           P               Q                   R                S
      B           R               S                   P                Q
      C           S               P                   Q                R
      D           S               R                   Q                P
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8   The diagram shows the structure of part of a DNA molecule.
    What does X represent?
    A    amino acid
    B    base
    C    carbon
    D    protein
9   Which statement about enzymes is correct?
    A    Enzymes become part of the product.
    B    Lowering the pH always slows down the reaction rate.
    C    Raising the temperature always increases the reaction rate.
    D    The specificity of an enzyme depends on the shape of its active site.
10 Which enzyme is used to produce clear apple juice?
    A    amylase
    B    lipase
    C    pectinase
    D    protease
11 Which structure would be found in large numbers in cells that have a high energy requirement?
    A    chloroplast
    B    endoplasmic reticulum
    C    large vacuole
    D    mitochondrion
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12 What must be increased in the diet of a person suffering from constipation?
    A    fats
    B    fibre
    C    iron
    D    protein
13 Which disease can be caused by a deficiency of iron in the diet?
    A    anaemia
    B    kwashiorkor
    C    marasmus
    D    rickets
14 The diagram shows the human alimentary canal, with a string marked in metres beside it.
                                                             oesophagus
                                                 0
                                                3
                            string marked
                            in metres
                                                4
                                                9              anus
    How long is the small intestine?
    A    2m             B     6m            C    8m             D     9m
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15 The graph shows the concentration of oxygen in the air spaces of a green leaf of a plant during a
   12-hour period.
                        concentration
                        of oxygen in
                        air spaces                            X
                                                           time
    Which statement about carbon dioxide in the air spaces during time X is correct?
    A    Carbon dioxide is being produced because the rate of photosynthesis is greater than the rate
         of respiration.
    B    Carbon dioxide is being produced because the rate of respiration is greater than the rate of
         photosynthesis.
    C    Carbon dioxide is being used because the rate of photosynthesis is greater than the rate of
         respiration.
    D    Carbon dioxide is being used because the rate of respiration is greater than the rate of
         photosynthesis.
16 What is a description of transpiration?
    A    exchange of gases between the leaf and the atmosphere
    B    loss of water vapour from the leaves and stems of a plant
    C    movement of water from the roots to the leaves
    D    movement of water through the cells of the leaf
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17 The diagram shows the vessels associated with the flow of fluids to and from body cells.
    Which is the lymph vessel?
                                          D                        B
18 The diagram shows a cross-section through a human blood vessel.
                                                         elastic and fibrous
                                                         connective tissue
                                                         muscle layer
    Which type of blood vessel does the diagram show?
    A    an artery
    B    a capillary
    C    a vein
    D    a ventricle
19 Which are both chemical barriers to the transmission of pathogens?
    A    mucus and stomach acid
    B    mucus and white blood cells
    C    skin and hairs in the nose
    D    skin and stomach acid
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20 The table shows some of the changes that occur during breathing.
                                                from contracted      from relaxed
                                                   to relaxed        to contracted
                            diaphragm                      P                X
                      external intercostals                Q                Y
                      internal intercostals                R                Z
    Which changes occur to cause inspiration?
    A    P, Q and Z     B     X, Q and R        C    X, Y and R      D    X, Y and Z
21 In an experiment to investigate anaerobic respiration, two bottles are set up in a warm room, as
   shown.
                              P                                  Q
                                      balloon                        balloon
                                        sugar, yeast                     yeast
                                        and water                        and water
    What would happen to each balloon after one day?
                          A                                                     B
                 P                Q                                  P                 Q
                          C                                                     D
                 P                Q                                  P                 Q
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22 The graph shows the lactic acid concentration in blood during and after exercise.
                                       1.0
                                                                         Z
                   blood lactic acid
                   concentration       0.5
                   / mg dm–3
                                                    exercise                      recovery
                                        0
                                             0      5        10    15        20     25       30
                                                              time / minutes
    The continuation of which process accounts for the shape of the graph at Z?
    A    deep breathing
    B    high heart rate
    C    high rate of breathing
    D    movement of lactic acid from the muscles
23 What is the most important function of sweating?
    A    to remove excess heat from the body
    B    to remove excess salts from the body
    C    to remove excess urea from the body
    D    to remove excess water from the body
24 Four effects of a specific hormone are listed.
               ●    increased blood pressure
               ●    increased blood glucose concentration
               ●    increased rate of respiration
               ●    reduced blood flow to the gut
    What is this hormone?
    A    adrenaline
    B    glucagon
    C    insulin
    D    testosterone
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25 The diagram shows a person sweating in hot weather.
    What part is played by sweat glands during the process of sweating?
    A       effector
    B       receptor
    C       sense organ
    D       stimulus
26 The diagram shows a synapse in a reflex arc.
                                        P                    Q
    What are the identities of the two neurones and in which direction does the neurotransmitter
    pass?
                                            direction of passage
                neurone P   neurone Q
                                            of neurotransmitter
        A          motor       relay               P→Q
        B          motor     sensory               P→Q
        C          relay      motor                Q→P
        D          relay     sensory               Q→P
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27 The immune system recognises pathogens and attacks them.
    Which feature of pathogens triggers this response?
    A       antibodies
    B       antibiotics
    C       antigens
    D       memory cells
28 Which environmental factor is not always a requirement for seed germination?
    A       light
    B       oxygen
    C       suitable temperature
    D       water
29 Which row shows the adaptive features of sperm cells?
                    flagellum       jelly coat   mitochondria
        A            absent          absent          present
        B            absent          present         absent
        C           present          absent          present
        D           present          present         absent
30 In some mammals the allele for brown coat colour is dominant to the allele for white coat colour.
    Which percentage of offspring will be white if a cross is made between two heterozygous
    mammals?
    A       0%                  B   25%          C     50%        D   100%
31 Which term is defined as a length of DNA that codes for a protein?
    A       amino acid
    B       chromosome
    C       gene
    D       mutation
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32 The following are involved in protein synthesis.
               1   amino acids assembled in order
               2   mRNA moves to the cytoplasm
               3   mRNA passing through a ribosome
               4   DNA in the nucleus
    In which order do they become involved when proteins are made?
    A    1→3→2→4
    B    3→2→1→4
    C    4→2→3→1
    D    4→3→2→1
33 What makes tongue rolling an example of discontinuous variation?
    A    A person can roll their tongue only when they are young.
    B    There are many different types of tongue rollers.
    C    Tongue rolling has to be learnt.
    D    Tongue rolling is something that a person either can or cannot do.
34 The distribution of the sickle-cell allele in human populations varies in different areas of the world.
    What is an explanation for this difference?
    A    People that are heterozygous for the sickle-cell allele have a resistance to cholera.
    B    People that are heterozygous for the sickle-cell allele have a resistance to malaria.
    C    People that are heterozygous for the sickle-cell allele are more likely to suffer from anaemia.
    D    People with sickle-cell anaemia have more alleles.
35 Nitrogen in the air cannot be used by plants until it is in the form of nitrates.
    Which two processes convert nitrogen from the air into nitrates?
    A    decomposition of faeces and nitrification
    B    denitrification and lightning
    C    nitrogen fixation by bacteria and denitrification
    D    nitrogen fixation by bacteria and lightning
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36 What is shown by the widest block in a pyramid of numbers for a grassland ecosystem?
    A       all the consumers in the pyramid
    B       the carnivores in the pyramid
    C       the organisms at the top of the pyramid
    D       the producers in the pyramid
37 The diagrams show the depth and rate of breathing in a person at 12.00 pm and 1.00 pm.
                             12.00 pm                                                   1.00 pm
                      0.5 dm3
                                                              volume
volume
         0      10    20      30   40       50   60     70             0   10   20     30    40       50   60   70
                           time / seconds                                            time / seconds
    What happens to the person’s breathing between 12.00 pm and 1.00 pm?
                    depth                rate
                 of breathing        of breathing
        A        decreases              decreases
        B        decreases              increases
        C         increases             decreases
        D         increases             increases
38 Ligase enzymes are used in genetic engineering to
    A       cut open plasmid DNA.
    B       insert plasmids into bacteria.
    C       isolate the DNA making up a human gene.
    D       join human DNA to plasmid DNA.
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39 What is not a reason for conservation programmes?
    A    to introduce new species
    B    to maintain nutrient cycles
    C    to maintain resources
    D    to protect vulnerable environments
40 Some examples of the waste products of human activity are discarded household rubbish,
   excess fertiliser, industrial chemicals and untreated sewage.
    Which of these can both cause increased growth of aquatic plants?
    A    chemical waste and discarded household rubbish
    B    discarded household rubbish and excess fertiliser
    C    excess fertiliser and untreated sewage
    D    untreated sewage and chemical waste
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© UCLES 2017                                                         0610/21/O/N/17