Diabetes Insipidus and SIADH - NEET PG
& INICET MCQs
Diabetes Insipidus MCQs
SIADH MCQs
1. 1. A patient presents with polyuria and polydipsia. Water deprivation test shows no
change in urine osmolality. After desmopressin, urine osmolality increases. What is the
diagnosis?
A) Nephrogenic Diabetes Insipidus
B) Central Diabetes Insipidus
C) SIADH
D) Primary polydipsia
Answer: B) Central Diabetes Insipidus
2. 2. Which of the following drugs commonly causes nephrogenic diabetes insipidus?
A) Lithium
B) Carbamazepine
C) Hydrochlorothiazide
D) Desmopressin
Answer: A) Lithium
3. 3. In Diabetes Insipidus, you expect which combination of findings?
A) Hyponatremia + low plasma osmolality
B) Hypernatremia + high plasma osmolality
C) Hyponatremia + high plasma osmolality
D) Hypernatremia + low plasma osmolality
Answer: B) Hypernatremia + high plasma osmolality
4. 4. In Central Diabetes Insipidus, the drug of choice is:
A) Hydrochlorothiazide
B) Desmopressin
C) Vasopressin
D) Tolvaptan
Answer: B) Desmopressin
5. 5. A patient with small cell lung carcinoma develops confusion. Serum sodium is 118
mEq/L. Urine sodium is high and serum osmolality is low. Most likely diagnosis?
A) Diabetes Insipidus
B) SIADH
C) Conn’s syndrome
D) Addison’s disease
Answer: B) SIADH
6. 6. The first-line treatment for asymptomatic SIADH is:
A) IV normal saline
B) Fluid restriction
C) Demeclocycline
D) Tolvaptan
Answer: B) Fluid restriction
7. 7. Which drug is LEAST likely to cause SIADH?
A) Carbamazepine
B) SSRIs
C) Lithium
D) Vincristine
Answer: C) Lithium
8. 8. All are features of SIADH EXCEPT:
A) Hyponatremia
B) Low plasma osmolality
C) Hypovolemia
D) High urine osmolality
Answer: C) Hypovolemia
9. 9. Vasopressin receptor antagonist used in SIADH is:
A) Desmopressin
B) Hydrochlorothiazide
C) Tolvaptan
D) Spironolactone
Answer: C) Tolvaptan
