Topic: BIOCHEMISTRY
RESEARCH ACTIVITY.
CASE
An 18 year old, moderately obese girl presents
with symptoms of breathlessness, wheezing, coughing
and uneasiness in breathing after doing work for short
amounts of time. She complained that this had been going
for a few years whenever she was exposed to dust or was
in a dusty environment. Recently it had gotten worse to
the point where she couldn’t breathe properly even after
the smallest of tasks that required physical exertion.
1. PROBABLE DIAGNOSIS
A: Breathlessness after not being able to breathe after
the smallest physical exertion would indicate to issues
regarding her obesity.
However since she mostly comaplained of this, after being
in a dusty environment, it would point to a possible dusty
allergy.
Since this has been going on for a long time, accompanied
with wheezing, it could be ASTHMA.
2. RECURRING TESTS DATA
A: Subsequent blood tests showed increased levels of IgE.
Blood report showed >1000 IU/mL whereas the normal
ranges for an adult should be 28-140 IU/mL for IgE levels.
3. SPECIAL TESTS DONE IF ANY
A: A blood test was done for Allergen-Aspergillus
Fumigatus (fungus) by the ImmunoCAP
(Fluroroenzymeimmunoassay) which came back
negative, implying that the ASTHMA was not caused by
any exposure to fungus or black mold.
CASE:
A 23 year old woman presented with fever and
weakness to the emergency department. She has had fever,
fatigue, nausea and vomitting along with diarrhoea for the
past 7-10 days and progressively getting worse; Dengue
NS1 antigen was positive which indicated. Haemoglobin,
hematocrit and RBC count was all normal. ESR was
elevated. Abnormal blood counts suggests inflammatory
response.
1. PROBABLE DIAGNOSIS
A: The positive antigen for dengue DONE BY ELISA, the
elevated ESR shows that it’s DENGUE
2. RECURRING TESTS DATA
A: TLC was lower than the normal range at 2.15 thou/
mm^3 for 4.00-10.00
3. SPECIFIC TESTS DONE IF ANY
A: NO SPECIFIC TESTS DONE.
CASE :
A 24 year old male presented with pain in
abdomen along with bloating, constipation, nausea and
vomitting along with full body fatigue and fever with loss
of appetite. There is also muscle weakness. Blood tests
showed positive for Widal test. The RBC and WBC count
were all within normal ranges.
1. PROBABLE DIAGNOSIS
A: Positive test for Widal test shows that the patient has
TYPHOID.
2. RECURRING TESTS DATA
A: There are presence of antibodies to Salmonella
3. SPECIAL TESTS DONE IF ANY
A: WIDAL TEST done to check for Typhoid.
CASE:
A 23 year old male presents with pain in upper
abdomen. There is yellowing of his eyes and skin, pruritis.
He has complains of nausea and vomitting. A complete
blood count shows hemoglobin, hematocrit, RBC’s and
WBC’s all within their normal ranges. The platelet count is
also normal. Liver functions tests shows a slight elevation
in levels of ALT and AST.
1. PROBABLE DIAGNOSIS
A: CONJUGATED HYPERBILIRUBINEMIA (JAUNDICE AS
AN INDICATOR)
2.RECURRING TESTS DATA
A: Tests done showed increased levels of direct bilirubin.
3. SPECIAL TESTS DONE IF ANY
A: NO SPECIAL TESTS DONE.
CASE:
A 51 year old man presented to the emergency
clinic with onset of acute pain in his chest. He was
conscious yet said that the pain in his chest on the pain
scale would be greater than 10. Upon consulting a
cardiologist and conducting multiple blood tests over the
course of 5 days along with ECG’s, he is shown to have
symptoms of myocardial infarction.
1. PROBABLE DIAGNOSIS
A: ACUTE MYOCARDIAL INFARCTION
2. RECURRING TESTS DATA
A: The chemistry showed increased levels of LDH initiall
followed by decrease in the LDH levels as treatment went
began.
The hemotology levels initially showed an increase in the
levels of D-Dimer but slowly decreased upon treatment.
The immunochemistry showed high levels of ferritin at
first but slowly decreased as the treatment went on.
3. SPECIAL TESTS DONE IF ANY
A: C REACTIVE PROTEIN
TEST DONE BY VIDAS MACHINE (ELFA METHOD)
CASE:
A 22 year old female comes for a general physical
check up. Her blood report shows low haemoglobin, low
levels of MCV, MCH and MCHC but high levels of Red Cell
Distribution Width (RDW). Her platelet count is within
normal ranges.
1. PROBABLE DIAGNOSIS
A: ANAEMIA
2. RECURRING TESTS DATA
A: LOW HAEMOGLOBIN
LOW MCV
LOW MCH
LOW MCHC
HIGH LEVELS OF Red Cell Distribution
3. SPECIAL TESTS DONE IF ANY
A: NO SPECIAL TESTS DONE
Bangalore
Baptist
Hospital
,csne.,.lll)'mlY-':k H-2011-0095
I MC 2009
1
LABORATORY REPORT
Name : MISHMA TOPPO : AA408083
MRD No.
Referred By : SATHYAVANI C. : OPORD00026 30579
Lab No.
Age : 22 Year(s) 9 Month(s) 18 Day(s)
Sex : Female
Ordered Date 1O-Feb-2022 18:41 :04 : 11-Feb-2022 08:40:32
Reported on
Collected Date 10-Feb-2022 18:43:43
Test Result Units Biological Reference Interval
Hematology
CBC(Complete Blood Counts) -Automated
Specimen : EDTA Blood Sample
Haemoglobin g/dl 12.0 - 16.0
Method : Cyanmethemoglobin 111/
Haematocrit(PCV) 35.7 % 36-46
Method : Coulter Principle ( lmpedence)
Total RBC Count 5.49 X 10"6/mm"3 3.80 - 4.80
Method : Coulter Principle ( lmpedence)
Total WBC count 8.1 x10"3/mm"3 4.0 -10.0
Method : Differential Lysis using Coulter Principle
Neutrophils 58 % 45- 75
Lymphocytes 30 % 20-40
Monocytes 6 % 2 - 10
Eosinophils 6 % 1-6
Method : DC by Absorbance Cytochemistry with volume
Basophils 0 % 0-2
Method : Coulter principle
MCV 65.01 FL 80 -100
Method : Coulter Principle ( lmpedence)
MCH
Method : Coulter Principle ( lmpedence)
20.2/
. PG 27.0- 32.0
"·
MCHC 31.0 g/dl 31.0-37.0
Method : Coulter Principle ( lmpedence)
Red Cell Distribution Width (RDW) 15.2/ % 11.6-14.0
Methoo : Coulter Principle ( lmpedence)
Platelet Count 227 x10"3/mm"3 150 - 400
IH{.0AI.AO!A)\0'KA JHIA'f, 'vii) 11'~1L1
RCll.'I\ o ~1449
CASE:
A 51 year old man presents with pain in upper
right abdomen.Upon doing radiology scans and Liver
Function Tests, there are findings of an enlarged liver. The
biliary system and gall bladder show multiple radiolucent
calculi, some of them showing faint hyperdense faci. There
is thickening in the wall of the urinary bladder, mild
prostomegaly and a mildy thickening in the appendix. The
LFT shows a slightly increased level of direct bilirubin.
There are increased levels of AST and ALT.
1. PROBABLE DIAGNOSIS
A: INFLAMMATION OF THE BILE DUCT
2. RECURRING TESTS DATA
A: INCREASED LEVELS OF DIRECT BILIRUBIN
3. SPECIAL TESTS DONE IF ANY
A: NO SPECIAL TESTS DONE
CASE:
A 65 year old female has elevated fasting and post
meal plasma glucose levels. Her fasting glucose was 90 mg/
dL and her post meal glucose was 162 mg/dL.
1. PROBABLE DIAGNOSIS
A: PRE DIABETES/ DIABETES
2. RECURRING TESTS DATA
A: INCREASED POST MEAL GLUCOSE LEVELS
3. SPECIAL TESTS DONE IF ANY
A: NO SPECIAL TESTS DONE.
CASE:
A 50 year old man presents to the clinic with history
of anaemia, he has occassional episodes of fatigue and
complaints of occassional tingling of feet.
1. PROBABLE DIAGNOSIS
A: VITAMIN B12 DEFICIENCY as the levels of Vitamin B12
is low and an additional test done to check for testosterone
levels showed low testosterone levels. Low levels of VitB12
are associated with a higher risk of VitB12 deficiency.
2. RECURRING TESTS DATA
A: LOW LEVELS OF VITAMIN B12
3. SPECIAL TESTS DONE IF ANY
A: TEST TO CHECK FOR TESTOSTERONE LEVELS WAS
DONE BY ELECTRO-CHEMILUMINESCENCE METHOD.
Bangalore
Baptist
Hospital
H-2011 •0095
LABORATORY REPORT
Name : MAITAN TOPPO MRD No. : AA520265
Referred By : DR. DHANASEKARAN.D Lab No. : OPORD0002200453
Age : 50 Year(s) 10 Month(s) 5 Day(s) Sex : Male
Ordered Date : 13-Aug-2020 6:57:11AM Reported on : 13-Aug-2020 10:24:13 am
Collected Date : 13-Aug-2020 7:17:41AM
Test Result Units Biological Reference Interval
lmmunochemistry
Vitamin 812
Specimen : Serum
- pg/ml Normal range -197-771:
Vitamin B12 188.1
Deficiency (WAO) < 150
Method : Electro - Chemiluminescence
Vitamin 0/ 03 for screening (25 Hydroxy cholecalclferol)
Specimen : Serum
ng/ml Desirable greater than I equal to 30 ,
Vitamin D ( 25 Hydroxy Cholecalclferol) 5.70
Method : Electro - Chemiluminescence ..:---
Testosterone - Total
Specimen : Serum
ng/ml Cyclic Women: 0.1 to 0.9 ng/ml
Testosterone - Total 1.77
Men: 3 to 10.6 ng/ml
Method : ELFA
Entere d by:
Ms. Latha This Is an interim report. Final report follow s.
(Lab Techni cian)
1.PROBABLE DIAGNOSIS
A: HYPERTHYROIDISM
2. RECURRING TESTS DATA
A: HIGH LEVELS OF T3, T4 AND TSH
3. SPECIAL TESTS DONE IF ANY
A: NO SPECIAL TESTS DONE
