BIO 101
Lecture 1
Introductory Biology
BIO-101
Amir Faisal
Introduction
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BIO 101
Lecture 1
Overview
• Introduction to the course
• Why Study Biology
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BIO 101
Lecture 1
Course Instructors
Dr. Amir Faisal (lead)
Dr. Muhammad Tariq
Dr. Safee Ullah Chaudhary
Head TAs:
Salman Tuasene Khawaja 24100162@lums.edu.pk
Paloma Maryam 24100050@lums.edu.pk
Tutorials can be organized with the Teaching Assistants
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BIO 101
Lecture 1
Contact Information
Dr. Amir Faisal Dr Muhammad Tariq
SBASSE-Biology, Room 9-317A Email: m.tariq@lums.edu.pk
Extension: 8453
Email: amir.faisal@lums.edu.pk Dr Safee Ullah Chaudhary
Email: safeeullah@lums.edu.pk
Office Hours
Monday: 11:00 – 1:30 PM (or by appointment)
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BIO 101
Lecture 1
Teaching Assistants
No. Names Roll Numbers
1 Salman Tuasene Khawaja 24100162@lums.edu.pk
2 Paloma Maryam 24100050@lums.edu.pk
3 Hamza Sajjad 24100262@lums.edu.pk
4 Muneeza Hassan 25100084@lums.edu.pk
5 Mahnoor Sakina Naqvi 25100322@lums.edu.pk
6 Nabeeha Fawad 25100185@lums.edu.pk
7 Khadija Badar 25100119@lums.edu.pk
8 Aleena Shahid Toor 25100268@lums.edu.pk
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BIO 101
Lecture 1
Course Overview
Goal
BIO101 is intended to provide students a broad overview of biology as it stands today!
Contents (to be covered in 5 modules)
Macromolecules and Cell Biology
Genes and Development
Omics and Systems Biology
Recombinant DNA Technology
Human Diseases and Drug Discovery
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BIO 101
Lectures and Exam Schedule Lecture 1
DATE LECTURE TOPICS INSTRUCTOR READING MATERIAL
Lecture # MODULE-I: Macromolecules and Cell Biology
1 Biology: Life AF Chapter 1: p2-17
2 Molecules of Life I; Proteins AF Chapter 2: p22-51
Molecules of Life II; Carbohydrates, Lipids and Nucleic AF
3 Chapter 4: p51-66
Acids
4 Cell Structure AF Chapter 5: p77-118
5 Cell Communication AF Chapter 7: p126-140
6 Cell Cycle and Cell Division AF Chapter 11: p206-225
7 Generation and utilization of energy by cells AF Chapter 9 & 10: p165-200
EXAM-1 (covering lectures 1-7) February 12th, 2023
MODULE-2: Genes and Development
8 From DNA to Phenotype I-transcription MT Chapter 13: p260-288
9 From DNA to Phenotype II-translation MT Chapter 14; p290-300
10 From DNA to Phenotype III-translation MT Chapter 14; p290-300
11 Genetics I MT TBA
12 Genetics II MT TBA
13 Genetics III
14 Development I MT TBA
15 Development II MT TBA
17/01/2023 EXAM-2 (covering lectures 8-15) March 12th, 2023
BIO 101
Lecture 1
Lectures and Exam Schedule
DATE LECTURE TOPICS INSTRUCTOR READING MATERIAL
MODULE-3: The World of Omics
16 DNA & Protein Sequences SU Mount: Chapter 1, 2
17 Sequence Comparison SU Mount: Chapter 3
18 RNA & Protein Structures SU Rastogi: Chapter 1, 2
19 Structure Comparison SU Rastogi: Chapter 12
20 Computational Approaches to Structural Modelling SU Rastogi: Chapter 13
MODULE-4: Recombinant DNA and Genome editing
21 Recombinant DNA Technology -Cloning and Expression AF Chapter 18: p374-382
22 Genome Editing CRISPR – Cas9 AF
EXAM-3 (covering lectures 16-22) April 9 , 2023
th
MODULE-5: Human Diseases and Drug Discovery
24 Nervous system AF
Immune System AF Chapter 42: p856-875
25 Human Pathogens (Viruses and Bacteria) AF Chapter 26: p525-545
26 Cancer AF TBA
27 Drug Development & Delivery AF TBA
28 Biotechnology: Stem Cells and Personalized medicine AF TBA
EXAM-4 (covering lectures 24-28) May 8 , 2023
th
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BIO 101
Lecture 1
Textbook
Life
The Science of Biology
10th Edition
Sadava
Hillis
Heller
Berenbaum
Copies of different editions are available in the library
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BIO 101
Lecture 1
Other Resources
Wikipedia, Google, etc
http://www.ncbi.nlm.nih.gov/guide/literature/
- Bookshelf
http://www.ncbi.nlm.nih.gov/pubmed/
- Home to electronic scientific journals
http://www.ncbi.nlm.nih.gov/omim/
- Information about gene/protein function
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BIO 101
Lecture 1
Study Aids
Ask questions!
See Instructors and TAs and during office hours
Attend tutorials organized by TAs
Study groups HIGHLY recommended
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BIO 101
Lecture 1
Evaluation
Exam-1 (Lectures 01-07; 12-02-23) 20%
Exam-2 (Lectures 08-15; 12-03-23) 20%
Exam-3 (Lectures 16-23; 09-04-23) 20%
Exam-4 (Lectures 24-28; 08-05-23) 20%
Attendance Quiz 10%
Assignments 10%
Note
All exam questions will be multiple choice
Grading will be relative
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B on mean
BIO 101
Lecture 1
Assignments
Two assignments; one each before the Exam 2 and Exam 4
40 random groups of 5 students each. Can be checked on LMS
TAs will provide further information about the assignments
All assignments to be submitted before Exams. Late submissions will not be
counted
Each Assignment will be 5%
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Lecture 1
Makeup Examinations
Only under extreme circumstances
• Hospitalization
• Death in family
• Written evidence required
• Exam questions will be essay type
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BIO 101
Lecture 1
Harassment Policy
SSE, LUMS and particularly this class, is a harassment free zone. There is absolutely zero tolerance for any
behaviour that is intended or has the expected result of making anyone uncomfortable and negatively impacts
the class environment, or any individual’s ability to work to the best of their potential.
If you think that you may be a victim of harassment, or if you have observed any harassment occurring in the
purview of this class, please reach out and speak to me. If you are a victim, I strongly encourage you to reach
out to the Office of Accessibility and Inclusion at oai@lums.edu.pk or the Sexual Harassment Inquiry
Committee at harassment@lums.edu.pk for any queries, clarifications, or advice. You may choose to file an
informal or a formal complaint to put an end of offending behavior. You can find more details regarding the
LUMS sexual harassment policy here.
To file a complaint, please write to harassment@lums.edu.pk.
SSE’s Council on Belonging and Equity is committed to devising ways to provide a safe, inclusive and respectful
learning environment for students. cbe.sse@lums.edu.pk
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BIO 101
Lecture 1
Student Code of Conduct
Maintaining Decorum
• All members of the LUMS community share the responsibility to maintain a
comfortable and congenial environment at LUMS
Appropriate Dress
• The dress should reflect decency and be according to cultural and social norms of
our society.
Eating and Drinking
• Food and drinks, with the exception of water, are not allowed in the classroom,
discussion rooms, laboratories and the Library.
Keeping the Campus Clean
• No littering on campus, inside or outside classroom.
No Smoking
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Lecture 1
Honor Code
ON OFF
A student-teacher relationship is purely based on honesty, integrity and inspiration
A student performs all academic work, assignments, exams, quizzes honestly and
never gets involved in any unfair activity falling under academic dishonesty like
cheating, unauthorized aid of any kind, plagiarism etc.
Any instances of academic dishonesty in this course (intentional or unintentional) will
be dealt with swiftly and severely.
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BIO 101
Lecture 1
Cheating
Cheating on any exam will result in a score of zero for that exam
Cheating on two exams will culminate in an automatic “F” in the
course and a report to DC
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BIO 101
Lecture 1
What is Biology?
Scientific study of living things (organisms)
Common set of chemicals
Cells are building blocks of organisms
Cells convert molecules obtained from environment into new biological molecules
Extract energy from the environment for the biological work
Genetic information with universal genetic code to assemble proteins
Similarities in fundamental set of genes
Exist in populations, evolve through genetic variations over time
Self regulate their internal environment – survive!
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BIO 101
Lecture 1
Why Study Biology?
Health Food Study of
Environment
Basic Understanding Basic Understanding
Biofuels of human body of Plants
Study of pathogens Plant pathogens
and chronic diseases and diseases Synthetic
Biology
Biosensors Improving crop
Finding cures!
production
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BIO 101
Lecture 1
Why Study Biology?
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Learning Outcomes
After this course students should be knowledgeable about:
Features of different cell types
How cells communicate with other cells
Structure of genes and composition of genomes
How biological information is stored and retrieved
Modern approaches for probing informational databases and building
phylogenetic trees, etc
What are pathogens and how immune system works
How diseases occur and how they can be prevented or cured
And much more!!!
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BIO 101
Lecture 1
Development
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Animal and plant development
BIO 101
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Genetics
Genes, Genetics and Genomes
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BIO 101
Lecture 1
From Genotype to Phenotype
Recessive = b Dominant = B
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BIO 101
Lecture 1
Neuroscience
How the brain functions!
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BIO 101
Lecture 1
Extremophiles
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Life in extreme environments
BIO 101
Lecture 1
Viruses
The Dangerous Underworld!
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Lecture 1
Aging
Aging (& Disease)
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Lecture 1
Immune System
E. coli K12 Macrophage attacking E. coli
Working of the Immune System
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BIO 101
Lecture 1
Genetic Engineering
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BIO 101
Lecture 1
Of Fireflies and Jellyfish
Mitotic spindles in fly embryo
Molecular Biology of the Cell 6th
Edition
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BIO 101
Lecture 1
Personalized Genomics & Medicine
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Evolution
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