stain

affectingthe
effectable
through
ses

/
onset

enteral common
most
-
mostchallenging kinetics

oral (P0)
~

Lacidic environment

infection isy stemic

1peristalsisportal dependent
circulation

List metabolism
Routes of effect pass
trans
&
Administration -
~under the tongue
clocal Drugs sublingual capillary absorption into
effect/ for
↓ blood streams
Endotracheal systemic ↓ 1
(ET)
/ I effect
bypass faster
Inhalation / acting than
Istpass
nasal system metabolism p0

carity localized spray)

L
crhinocort
capillary absorption -a

asiancapillaryin raped
effect percentage
Caution localized systemic effectstill reaches

1
creams or
systemic systemicin
·stat
Crinkle
+x)many lower presence
o nes drugs percentage
effects
I preparation dependent

LLsy
a

still reaches
general
too
edicated
be stemic (flu vaccine) across

Skir can
are
penatrate
an
system
anesthesia
drugs
circulation
(cocaine
diffusion distribit seen

all direct CNS effect CNS

effectbut
contraindicated
in
pregnancy
layers expressedthe molecular weight+
molecule size :
along
nerve network
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