Material Safety Data Sheet

DOW CHEMICAL VIETNAM LLC

Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Print Date: 30.10.2019
DOW CHEMICAL VIETNAM LLC encourages and expects you to read and understand the entire
(M)SDS, as there is important information throughout the document. We expect you to follow the
precautions identified in this document unless your use conditions would necessitate other appropriate
methods or actions.

1. PRODUCT AND COMPANY IDENTIFICATION

Product name: Propylene Glycol USP/EP

Recommended use of the chemical and restrictions on use

Identified uses: We recommend that you use this product in a manner consistent with the listed use.
If your intended use is not consistent with the stated use, please contact your sales or technical
service representative. Uses in Coatings, consumer Use in Cleaning Agents, consumer Functional
Fluids, consumer Consumer use in agrochemicals. Other Consumer Uses Humectant and solvent
for: Foodstuffs. Flavours. Fragrances. Cosmetics. Pharmaceuticals. Personal care applications.
Manufacture of substance, industrial Distribution of substance, industrial Formulation & (re)packing of
substances and mixtures, industrial Use in laboratories, industrial Use as binders and release agents,
professional Not for use in cat food. We recommend that you use this product in a manner consistent
with the listed use. If your intended use is not consistent with the stated use, please contact your sales
or technical service representative. Humectant and solvent for: Foodstuffs. Flavours. Cosmetics.
Pharmaceuticals. Personal care applications. Not for use in cat food.

COMPANY IDENTIFICATION
DOW CHEMICAL VIETNAM LLC
UNIT 503, 5F, CENTRE POINT OFFICE BLDG
106 NGUYEN VAN TROI ST, WARD 8
PHU NHUAN DISTRICT
HO CHI MINH CITY
VIET NAM

Customer Information Number: 84-28-3999-0008

SDSQuestion@dow.com
Fax: 84-28-3999-0009

EMERGENCY TELEPHONE NUMBER

24-Hour Emergency Contact: +84 28-3999-0007
Local Emergency Contact: 28-3999-0007

2. HAZARDS IDENTIFICATION
GHS Classification
This product is not hazardous per the Globally Harmonized System of Classification and Labelling
(GHS).

Other hazards

® ™ Trademark of The Dow Chemical Company ("Dow") or an affiliated Page 1 of 12

company of Dow
Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

No data available

3. COMPOSITION/INFORMATION ON INGREDIENTS

This product is a substance.

Component CASRN Concentration

Propylene glycol 57-55-6 > 99,8 %

4. FIRST AID MEASURES

Description of first aid measures
General advice:
If potential for exposure exists refer to Section 8 for specific personal protective equipment.

Inhalation: Move person to fresh air; if effects occur, consult a physician.

Skin contact: Wash off with plenty of water.

Eye contact: Flush eyes thoroughly with water for several minutes. Remove contact lenses after the
initial 1-2 minutes and continue flushing for several additional minutes. If effects occur, consult a
physician, preferably an ophthalmologist.

Ingestion: No emergency medical treatment necessary.

Most important symptoms and effects, both acute and delayed:

Aside from the information found under Description of first aid measures (above) and Indication of
immediate medical attention and special treatment needed (below), any additional important
symptoms and effects are described in Section 11: Toxicology Information.

Indication of any immediate medical attention and special treatment needed

Notes to physician: No specific antidote. Treatment of exposure should be directed at the control of
symptoms and the clinical condition of the patient.

5. FIREFIGHTING MEASURES
Extinguishing media

Suitable extinguishing media: Water fog or fine spray.. Dry chemical fire extinguishers..
Carbon dioxide fire extinguishers.. Foam.. Alcohol resistant foams (ATC type) are preferred.
General purpose synthetic foams (including AFFF) or protein foams may function, but will be
less effective..

Unsuitable extinguishing media: Do not use direct water stream.. May spread fire..

Special hazards arising from the substance or mixture

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Hazardous combustion products: During a fire, smoke may contain the original material in
addition to combustion products of varying composition which may be toxic and/or irritating. .
Combustion products may include and are not limited to:. Carbon monoxide.. Carbon dioxide..

Unusual Fire and Explosion Hazards: Container may rupture from gas generation in a fire
situation.. Violent steam generation or eruption may occur upon application of direct water
stream to hot liquids..

Advice for firefighters

Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. .
Use water spray to cool fire exposed containers and fire affected zone until fire is out and
danger of reignition has passed.. Fight fire from protected location or safe distance. Consider
the use of unmanned hose holders or monitor nozzles.. Immediately withdraw all personnel
from the area in case of rising sound from venting safety device or discoloration of the
container.. Burning liquids may be extinguished by dilution with water.. Do not use direct
water stream. May spread fire.. Move container from fire area if this is possible without
hazard.. Burning liquids may be moved by flushing with water to protect personnel and
minimize property damage..

Special protective equipment for firefighters: Wear positive-pressure self-contained

breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet,
coat, trousers, boots, and gloves).. If protective equipment is not available or not used, fight
fire from a protected location or safe distance..

6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures: Use appropriate safety
equipment. For additional information, refer to Section 8, Exposure Controls and Personal Protection.
Keep unnecessary and unprotected personnel from entering the area. Keep personnel out of low
areas.

Environmental precautions: Prevent from entering into soil, ditches, sewers, waterways and/or
groundwater. See Section 12, Ecological Information.

Methods and materials for containment and cleaning up: Contain spilled material if possible.
Small spills: Any absorbent material. Collect in suitable and properly labeled open containers. Wash
the spill site with large quantities of water. Large spills: Dike area to contain spill. Pump into suitable
and properly labeled containers. See Section 13, Disposal Considerations, for additional information.

7. HANDLING AND STORAGE

Precautions for safe handling: Product handled hot may require additional ventilation or local
exhaust. Spills of these organic materials on hot fibrous insulations may lead to lowering of the
autoignition temperatures possibly resulting in spontaneous combustion. See Section 8, EXPOSURE
CONTROLS AND PERSONAL PROTECTION.

Conditions for safe storage: Store away from direct sunlight or ultraviolet light. Keep container
tightly closed when not in use. Store in a dry place. Protect from atmospheric moisture. Store in the

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

following material(s): Stainless steel. Aluminum. Container lined with phenolic or epoxy-phenolic
FDA food contact approved coating. 316 stainless steel. Opaque HDPE plastic container.

Storage stability
Shelf life: Use within 24 Month

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters
If exposure limits exist, they are listed below. If no exposure limits are displayed, then no values are
applicable.
Component Regulation Type of listing Value
Propylene glycol US WEEL TWA 10 mg/m3

Exposure controls
Engineering controls: Use local exhaust ventilation, or other engineering controls to maintain
airborne levels below exposure limit requirements or guidelines. If there are no applicable exposure
limit requirements or guidelines, general ventilation should be sufficient for most operations. Local
exhaust ventilation may be necessary for some operations.

Individual protection measures

Eye/face protection: Use safety glasses (with side shields). If there is a potential for
exposure to particles which could cause eye discomfort, wear chemical goggles.
Skin protection
Hand protection: Chemical protective gloves should not be needed when handling
this material. Consistent with general hygienic practice for any material, skin contact
should be minimized.
Other protection: No precautions other than clean body-covering clothing should be
needed.
Respiratory protection: Respiratory protection should be worn when there is a potential to
exceed the exposure limit requirements or guidelines. If there are no applicable exposure limit
requirements or guidelines, wear respiratory protection when adverse effects, such as
respiratory irritation or discomfort have been experienced, or where indicated by your risk
assessment process. In misty atmospheres, use an approved particulate respirator.
The following should be effective types of air-purifying respirators: Organic vapor cartridge
with a particulate pre-filter.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance
Physical state Liquid.
Color Colorless
Odor Odorless
Odor Threshold No test data available
pH Not applicable
Melting point/range < -20 °C EC Method A1
Freezing point < -20 °C EC Method A1
Boiling point (760 mmHg) 184 °C at 752,46 mmHg EC Method A2

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Flash point closed cup 104 °C at 1.000,1 hPa EC Method A9 (PMCC)

Evaporation Rate (Butyl Acetate 0,01 Estimated.
= 1)
Flammability (solid, gas) Not applicable to liquids
Flammability (liquids) Not expected to be a static-accumulating flammable liquid.
Lower explosion limit 2,6 % vol Estimated.
Upper explosion limit 12,5 % vol Estimated.
Vapor Pressure 20 Pa at 25 °C EC Method A4
Relative Vapor Density (air = 1) 2,62 Literature
Relative Density (water = 1) 1,03 at 20 °C / 20 °C EC Method A3
Water solubility EC Method A6
Partition coefficient: n- log Pow: -1,07 Measured
octanol/water
Auto-ignition temperature > 400 °C at 100,01 kPa EC Method A15
Decomposition temperature No test data available
Dynamic Viscosity 43,4 mPa.s at 25 °C Literature
Kinematic Viscosity No test data available
Explosive properties Not explosive
Oxidizing properties No
Liquid Density 1,03 g/cm3 at 20 °C Literature
Molecular weight No data available
Percent volatility No data available
Pour point < -57 °C Literature

NOTE: The physical data presented above are typical values and should not be construed as a
specification.

10. STABILITY AND REACTIVITY

Reactivity: No data available

Chemical stability: Stable under recommended storage conditions. See Storage, Section 7.
Hygroscopic

Possibility of hazardous reactions: Polymerization will not occur.

Conditions to avoid: No data available

Incompatible materials: Avoid contact with: Strong acids. Strong bases. Strong oxidizers.

Hazardous decomposition products: Decomposition products depend upon temperature, air supply
and the presence of other materials.. Decomposition products can include and are not limited to:.
Aldehydes.. Alcohols.. Ethers.. Organic acids..

11. TOXICOLOGICAL INFORMATION

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Toxicological information appears in this section when such data is available.

Exposure routes
Ingestion, Inhalation, Skin contact, Eye contact.

Acute toxicity (represents short term exposures with immediate effects - no chronic/delayed
effects known unless otherwise noted)

Acute oral toxicity

Very low toxicity if swallowed. Harmful effects not anticipated from swallowing small amounts.

LD50, Rat, > 20.000 mg/kg

Information for components:

Propylene glycol
LD50, Rat, > 20.000 mg/kg

Acute dermal toxicity

Prolonged skin contact is unlikely to result in absorption of harmful amounts.

LD50, Rabbit, > 2.000 mg/kg No deaths occurred at this concentration.

Information for components:

Propylene glycol
LD50, Rabbit, > 2.000 mg/kg No deaths occurred at this concentration.

Acute inhalation toxicity

At room temperature, exposure to vapor is minimal due to low volatility.

LC50, Rabbit, 2 Hour, dust/mist, 317,042 mg/l No deaths occurred at this concentration.
Information for components:

Propylene glycol
LC50, Rabbit, 2 Hour, dust/mist, 317,042 mg/l No deaths occurred at this
concentration.

Skin corrosion/irritation
Based on product testing:
Prolonged contact is essentially nonirritating to skin.
Repeated contact may cause flaking and softening of skin.

Information for components:

Propylene glycol
Prolonged contact is essentially nonirritating to skin.
Repeated contact may cause flaking and softening of skin.

Serious eye damage/eye irritation

Based on product testing:
May cause slight temporary eye irritation.
Corneal injury is unlikely.
Mist may cause eye irritation.

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Information for components:

Propylene glycol
May cause slight temporary eye irritation.
Corneal injury is unlikely.
Mist may cause eye irritation.

Sensitization
Did not cause allergic skin reactions when tested in humans.

For respiratory sensitization:

No relevant data found.

Information for components:

Propylene glycol
Did not cause allergic skin reactions when tested in humans.

For respiratory sensitization:

No relevant data found.

Specific Target Organ Systemic Toxicity (Single Exposure)

Evaluation of available data suggests that this material is not an STOT-SE toxicant.

Information for components:

Propylene glycol
Evaluation of available data suggests that this material is not an STOT-SE toxicant.

Aspiration Hazard
Based on physical properties, not likely to be an aspiration hazard.

Information for components:

Propylene glycol
Based on physical properties, not likely to be an aspiration hazard.

Chronic toxicity (represents longer term exposures with repeated dose resulting in
chronic/delayed effects - no immediate effects known unless otherwise noted)

Specific Target Organ Systemic Toxicity (Repeated Exposure)

In rare cases, repeated excessive exposure to propylene glycol may cause central nervous system
effects.

Information for components:

Propylene glycol
In rare cases, repeated excessive exposure to propylene glycol may cause central nervous
system effects.

Carcinogenicity
Did not cause cancer in laboratory animals.

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Information for components:

Propylene glycol
Did not cause cancer in laboratory animals.

Teratogenicity
Did not cause birth defects or any other fetal effects in laboratory animals.

Information for components:

Propylene glycol
Did not cause birth defects or any other fetal effects in laboratory animals.

Reproductive toxicity
In animal studies, did not interfere with reproduction. In animal studies, did not interfere with fertility.

Information for components:

Propylene glycol
In animal studies, did not interfere with reproduction. In animal studies, did not interfere with
fertility.

Mutagenicity
In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.

Information for components:

Propylene glycol
In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.

12. ECOLOGICAL INFORMATION

Ecotoxicological information appears in this section when such data is available.

Ecotoxicity
Acute toxicity to fish
Material is practically non-toxic to aquatic organisms on an acute basis
(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).

LC50, Oncorhynchus mykiss (rainbow trout), static test, 96 Hour, 40.613 mg/l, OECD Test
Guideline 203

Acute toxicity to aquatic invertebrates

LC50, Ceriodaphnia dubia (water flea), static test, 48 Hour, 18.340 mg/l, OECD Test Guideline
202

Acute toxicity to algae/aquatic plants

ErC50, Pseudokirchneriella subcapitata (green algae), 96 Hour, Growth rate inhibition, 19.000
mg/l, OECD Test Guideline 201

Toxicity to bacteria
NOEC, Pseudomonas putida, 18 Hour, > 20.000 mg/l, Method Not Specified.

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Long-term (chronic) aquatic hazard

Chronic toxicity to aquatic invertebrates
NOEC, Ceriodaphnia dubia (water flea), semi-static test, 7 d, number of offspring, 13.020 mg/l

Persistence and degradability

Biodegradability: Material is readily biodegradable. Passes OECD test(s) for ready
biodegradability. Biodegradation may occur under anaerobic conditions (in the absence of
oxygen).
10-day Window: Pass
Biodegradation: 81 %
Exposure time: 28 d
Method: OECD Test Guideline 301F or Equivalent
10-day Window: Not applicable
Biodegradation: 96 %
Exposure time: 64 d
Method: OECD Test Guideline 306 or Equivalent

Theoretical Oxygen Demand: 1,68 mg/mg

Chemical Oxygen Demand: 1,53 mg/mg

Biological oxygen demand (BOD)

Incubation BOD
Time
5d 69.000 %
10 d 70.000 %
20 d 86.000 %

Photodegradation
Atmospheric half-life: 10 Hour
Method: Estimated.

Bioaccumulative potential
Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3).
Partition coefficient: n-octanol/water(log Pow): -1,07 Measured
Bioconcentration factor (BCF): 0,09 Estimated.

Mobility in Soil
Given its very low Henry's constant, volatilization from natural bodies of water or moist soil is
not expected to be an important fate process.
Potential for mobility in soil is very high (Koc between 0 and 50).
Partition coefficient (Koc): < 1 Estimated.

Results of PBT and vPvB assessment

This substance is not considered to be persistent, bioaccumulating and toxic (PBT). This
substance is not considered to be very persistent and very bioaccumulating (vPvB).

Other adverse effects

This substance is not on the Montreal Protocol list of substances that deplete the ozone layer.

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

13. DISPOSAL CONSIDERATIONS

Disposal methods: DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY
OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local
laws and regulations. Regulations may vary in different locations. Waste characterizations and
compliance with applicable laws are the responsibility solely of the waste generator. AS YOUR
SUPPLIER, WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR
MANUFACTURING PROCESSES OF PARTIES HANDLING OR USING THIS MATERIAL. THE
INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS
INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Information. FOR
UNUSED & UNCONTAMINATED PRODUCT, the preferred options include sending to a licensed,
permitted: Recycler. Reclaimer. Incinerator or other thermal destruction device. As a service to its
customers, Dow can provide names of information resources to help identify waste management
companies and other facilities which recycle, reprocess or manage chemicals or plastics, and that
manage used drums. Telephone Dow's Customer Information Group at 1-800-258-2436 or 1-989-
832-1556 (U.S.), or 1-800-331-6451 (Canada) for further details.

14. TRANSPORT INFORMATION

Classification for ROAD and Rail transport:

Not regulated for transport

Classification for SEA transport (IMO-IMDG):

Not regulated for transport
Transport in bulk Consult IMO regulations before transporting ocean bulk
according to Annex I or II
of MARPOL 73/78 and the
IBC or IGC Code

Classification for AIR transport (IATA/ICAO):

Not regulated for transport

This information is not intended to convey all specific regulatory or operational

requirements/information relating to this product. Transportation classifications may vary by container
volume and may be influenced by regional or country variations in regulations. Additional
transportation system information can be obtained through an authorized sales or customer service
representative. It is the responsibility of the transporting organization to follow all applicable laws,
regulations and rules relating to the transportation of the material.

15. REGULATORY INFORMATION

Based on our best knowledge, following regulations provide the requirements on trading, safety use,
transportation, labeling of chemicals in Vietnam:

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

Law No. 06/2007/QH12 on Chemicals, issued on November 21, 2007

Decree No. 113/2017/ND-CP, Specifying and Providing guidelines for implementation of certain
articles of the Law on chemicals (issued October 09, 2017).
Decree No. 104/2009/ND-CP, On Prescribing the List of Dangerous Goods and the Land-Road
Transport of Dangerous Goods (issued on November 9, 2009)
Decree No. 29/2005/ND-CP on Transportation of Dangerous Goods by Domestic Waterway (issued
on March 10, 2005).
Decree No. 43/2017/ND-CP, on Labeling of Goods (issued on June 01, 2017).
It is recommended the customer to check in the location of use of this product whether it is specifically
regulated for human perusal or veterinary applications, as food and pharmaceuticals additives or
packaging, domissanitary, and cosmetics, or even as controlled agent recognized as precursor to
drug, chemical weapons, and ammunition manufacture.

16. OTHER INFORMATION

Product Literature
Additional information on this and other products may be obtained by visiting our web page.

Revision
Identification Number: 99033322 / A634 / Issue Date: 29.10.2019 / Version: 1.6
Most recent revision(s) are noted by the bold, double bars in left-hand margin throughout this
document.

Legend
TWA 8-hr TWA
US WEEL USA. Workplace Environmental Exposure Levels (WEEL)

Full text of other abbreviations

AICS - Australian Inventory of Chemical Substances; ANTT - National Agency for Transport by Land
of Brazil; ASTM - American Society for the Testing of Materials; bw - Body weight; CMR - Carcinogen,
Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for Standardisation; DSL -
Domestic Substances List (Canada); ECx - Concentration associated with x% response; ELx -
Loading rate associated with x% response; EmS - Emergency Schedule; ENCS - Existing and New
Chemical Substances (Japan); ErCx - Concentration associated with x% growth rate response; ERG -
Emergency Response Guide; GHS - Globally Harmonized System; GLP - Good Laboratory Practice;
IARC - International Agency for Research on Cancer; IATA - International Air Transport Association;
IBC - International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals
in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization;
IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime
Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial Safety and Health Law
(Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemicals
Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a
test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of
Pollution from Ships; n.o.s. - Not Otherwise Specified; Nch - Chilean Norm; NO(A)EC - No Observed
(Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No
Observable Effect Loading Rate; NOM - Official Mexican Norm; NTP - National Toxicology Program;
NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic Co-operation and
Development; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent,
Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical
Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No
1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation,
Authorisation and Restriction of Chemicals; SADT - Self-Accelerating Decomposition Temperature;

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Product name: Propylene Glycol USP/EP Issue Date: 29.10.2019

SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TDG - Transportation of
Dangerous Goods; TSCA - Toxic Substances Control Act (United States); UN - United Nations;
UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very
Persistent and Very Bioaccumulative; WHMIS - Workplace Hazardous Materials Information System

DOW CHEMICAL VIETNAM LLC urges each customer or recipient of this (M)SDS to study it carefully
and consult appropriate expertise, as necessary or appropriate, to become aware of and understand
the data contained in this (M)SDS and any hazards associated with the product. The information
herein is provided in good faith and believed to be accurate as of the effective date shown above.
However, no warranty, express or implied, is given. Regulatory requirements are subject to change
and may differ between various locations. It is the buyer's/user's responsibility to ensure that his
activities comply with all federal, state, provincial or local laws. The information presented here
pertains only to the product as shipped. Since conditions for use of the product are not under the
control of the manufacturer, it is the buyer's/user's duty to determine the conditions necessary for the
safe use of this product. Due to the proliferation of sources for information such as manufacturer-
specific (M)SDSs, we are not and cannot be responsible for (M)SDSs obtained from any source other
than ourselves. If you have obtained an (M)SDS from another source or if you are not sure that the
(M)SDS you have is current, please contact us for the most current version.
VN

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