Duell 2018
Duell 2018
Duell 2018
Cognitive Development
journal homepage: www.elsevier.com/locate/cogdev
AR TI CLE I NF O AB S T R A CT
Keywords: The authors examined the association between working memory and response inhibition on the
Stroop Stroop task using a cross-sectional, international sample of 5099 individuals (49.3% male) ages
Working memory 10–30 (M = 17.04 years; SD = 5.9). Response inhibition was measured using a Stroop task that
Response inhibition included “equal” and “unequal” blocks, during which the relative frequency of neutral and in-
Development
congruent trials was manipulated. Competing stimuli in incongruent trials evinced inhibitory
functioning, and having a lower proportion of incongruent trials (as in unequal blocks) placed
higher demands on working memory. Results for accuracy indicated that age and working
memory were independently associated with response inhibition. Age differences in response
inhibition followed a curvilinear trajectory, with performance improving into early adulthood.
Response inhibition was greatest among individuals with high working memory. For response
time, age uniquely predicted response inhibition in unequal blocks. In equal blocks, age differ-
ences in response inhibition varied as a function of working memory, with age differences being
least pronounced among individuals with high working memory. The implications of considering
☆This research was supported by an award to Laurence Steinberg from the Klaus J. Jacobs Foundation and the Eunice Kennedy Shriver National Institute of Child
Health and Human Development grant RO1-HD054805.
⁎
Corresponding author at: Department of Psychology, Temple University, 6th Floor Weiss Hall, 1701 North 13th Street, Philadelphia, PA 19122, United States.
E-mail address: ntduell@temple.edu (N. Duell).
https://doi.org/10.1016/j.cogdev.2018.02.003
Received 14 September 2017; Received in revised form 21 February 2018; Accepted 23 February 2018
0885-2014/ © 2018 Elsevier Inc. All rights reserved.
N. Duell et al. Cognitive Development 47 (2018) 19–31
the association between response inhibition and working memory in the context of development
are discussed.
1. Introduction
Adolescence is a period during which individuals must learn to navigate the increasing academic, social, and personal challenges
they face. The ability to regulate behavior in favor of short- and long-term goals is one skill critical to mastering these challenges.
Response inhibition and working memory are two executive processes that facilitate the ability to engage in such goal-directed
behavior (DeLuca et al., 2003; Miller & Cohen, 2001). Research on adults indicates that response inhibition and working memory are
psychologically distinct (e.g., Friedman & Miyake, 2004), yet functionally concomitant processes (Davidson, Amso, Anderson, &
Diamond, 2006; Engle & Kane, 2004). Further, findings from some studies suggest that working memory facilitates response in-
hibition, such that individuals with high working memory demonstrate better performance on measures of response inhibition
compared to individuals with low working memory (e.g., Egner & Hirsch, 2005; Long & Prat, 2002; Miller & Cohen, 2001; Weldon,
Mushlin, Kim, & Sohn, 2013). However, such findings have not been replicated in samples that include adolescents. Understanding
the relation between these two processes at a time during which they are still developing (e.g., Huizinga, Dolan, & van der Molen,
2006) affords a more comprehensive picture of adolescent executive functioning. In the present study, we explored whether inter-
individual variation in working memory contributed to variation in response inhibition across different periods of development, using
a cross-sectional sample of individuals between the ages of 10 and 30 years.
Response inhibition − the ability to deliberately inhibit automatic or prepotent responses (Miyake, Friedman, Emerson, Witzki, &
Howerter, 2000) – is part of a family of functionally similar inhibitory processes responsible for regulating thoughts and actions
(Andrews-Hanna et al., 2011; Braver, 2012; Nigg, 2000). Cross-sectional studies of response inhibition indicate that inhibitory skills
continue maturing into the early twenties (Davidson et al., 2006; Luna et al., 2001; Velanova, Wheeler, & Luna, 2009), with evidence
to suggest that these age patterns are relatively consistent among individuals from various countries across the world (Steinberg et al.,
2017). Thus, adolescence is a time when individuals are still developing self-regulatory abilities. Understanding how to facilitate
inhibitory functioning during this sensitive period is important given the observed link between inhibitory function and academic
achievement, occupational success, law-abiding behaviors, and psychological well-being (Moffitt, Poulton, & Caspi, 2013).
Working memory, which also continues maturing into the early twenties (DeLuca et al., 2003; Huizinga et al., 2006; Luciana,
Conklin, Hooper, & Yarger, 2005), entails a set of cognitive processes responsible for the maintenance and manipulation of mentally
represented information, as well as attentional control (Cowan et al., 2005; Kane, Bleckley, Conway, & Engle, 2001). In many
conceptions of working memory, one of the crucial functions subserved by this system is the ability to hold current task goals in an
active, quickly retrievable state (Engle, 2002) and it is this domain-general facet of working memory that has been linked to in-
hibitory functioning (Kane & Engle, 2003). Researchers who advocate this view postulate that successful response inhibition requires
active maintenance of task goals in memory, which is achieved via efficient attentional control (Conway et al., 2005; Diamond, 2013;
Engle & Kane, 2004; Kuo, Stokes, & Nobre, 2012; Miyake et al., 2000). From this vantage point, working memory capacity refers to
the extent of an individual’s ability to control attention and actively maintain goals in mind (Engle, 2002).
One task well-suited for examining response inhibition in relation to goal maintenance in working memory is the Stroop task
(Kane & Engle, 2003; Long & Prat, 2002). On this standard measure of response inhibition (Friedman & Miyake, 2004; Huizinga et al.,
2006; MacLeod, 1991; Nee, Wager, & Jonides, 2007; Veroude, Jolles, Croiset, & Krabbendamn, 2013), participants are asked to
quickly and accurately indicate the color in which a word is displayed while ignoring its semantic meaning. On incongruent trials, a
color word is displayed in an incongruent color (e.g., the word ‘blue’ displayed in green font), requiring that participants inhibit the
prepotent response to read the word and instead respond on the basis of the word’s physical color. Response inhibition and the
resolution of cognitive conflict on incongruent trials not only requires efficient self-regulatory abilities, but also relies on attentional
resources and the active maintenance, in working memory, of the task goal (Kane & Engle, 2002; Marsh et al., 2006).
Response inhibition on the Stroop task is typically operationalized as the Stroop interference effect (Stroop effect) (Adleman et al.,
2002; Andrews-Hanna et al., 2011; Long & Prat, 2002; MacLeod, 1991; Morey et al., 2012) wherein performance on incongruent
trials is compared to performance on some variation of a baseline trial (e.g., Huizinga et al., 2006) such as congruent trials, in which
the color of the word matches its meaning (e.g., the word ‘blue’ displayed in the color blue) or neutral trials, where the presented
word is a non-color word (e.g., ‘math’ displayed in any color). Lower accuracy scores and slower response times on incongruent trials
relative to baseline trials reflect a larger Stroop effect. The Stroop effect is thought to result from cognitive conflict induced by
incongruent trials (Kane & Engle, 2003), which is exacerbated by a deficient ability to resist interfering stimuli (Andrews-Hanna
et al., 2011; Marsh et al., 2006). Additionally, researchers assert that the Stroop effect results from a failure to maintain the task goal
in active memory (Kane & Engle, 2003). In effect, individuals with stronger inhibitory control and greater working memory capacity
typically evince smaller Stroop effects compared to individuals with weak inhibitory control and low working memory (cf., Engle &
Kane, 2004). Thus, performance on the Stroop task captures information about both inhibitory function and working memory ca-
pacity.
Considering that executive functions such as response inhibition and working memory are not fully developed during the ado-
lescent years, one might expect that, compared to adults, adolescents evince a larger Stroop effect. However, cross-sectional ex-
aminations of Stroop performance yield inconsistent results, with findings from some studies indicating that adolescents evince a
larger Stroop effect with respect to response time (Huizinga et al., 2006) and accuracy (Marsh et al., 2006) compared to adults, other
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studies suggesting that these age differences are only observed for the Stroop effect for response time, but not accuracy (Schroeter,
Zysset, Wahl, & von Cramon, 2004), and still others finding no differences between adolescents and adults for either response time or
accuracy (Andrews-Hanna et al., 2011). The inconsistency of these findings may be explained in part by certain methodological
limitations. Importantly, very few cross-sectional studies of Stroop performance incorporate task manipulations that influence the
difficulty of the task. This is particularly important for developmental research on executive functioning, given previous work de-
monstrating that task difficulty influences the extent to which differences in both inhibitory control (Albert & Steinberg, 2011) and
working memory (DeLuca et al., 2003) are observed between adolescents and adults.
One task manipulation frequently employed in adult studies of Stroop performance is the relative frequency with which incon-
gruent and baseline trials are presented within a given task block (i.e., block type; Egner & Hirsch, 2005; Engle, 2002; Hutchison,
2011). Manipulations of block type are shown to affect the relative difficulty of the Stroop task by placing differential demands on
both working memory and inhibitory control (Davidson et al., 2006; Kane & Engle, 2003; Morey et al., 2012). Specifically, blocks
with a greater frequency of incongruent trials compared to baseline trials are easier than those with a lower frequency of incongruent
trials (and higher frequency of baseline trials) (see Kane & Engle, 2003). Incongruent trials remind participants of the task goal (to
focus on the color of the word). Thus, in blocks with a higher frequency of incongruent trials relative to baseline trials, working
memory demands are reduced because successful performance on the task does not require that participants actively engage in goal
maintenance. On the other hand, working memory demands are greater on blocks in which baseline trials are more frequent because
baseline trials, which have no conflicting stimuli, leave participants vulnerable to automatic responding (since there is no cognitive
conflict) rather than using the active representation of the task goal (i.e., to respond only on the basis of the word’s color) to guide
behavior. While prepotent responding without goal maintenance may lead to faster and more optimal performance on baseline trials,
performance on incongruent trials suffers because the lack of goal maintenance (or goal neglect, Morey et al., 2012) either diminishes
accuracy, increases response latency, or both. Viewed in this way, response inhibition on the Stroop task is undermined by low
working memory capacity.
Research comparing Stroop performance between adults with low and high working memory capacity reveals two important
findings: (1) individuals with high working memory capacity are less susceptible to Stroop interference (e.g., Kane & Engle, 2003;
Long & Prat, 2002), and (2) these working memory differences are exaggerated in blocks within which incongruent trials are rare
(e.g., Hutchison, 2011; Morey et al., 2012). Whether these findings hold true across different ages is yet to be determined. Whereas
high working memory may be associated with successful behavioral inhibition on the Stroop task across age, it may also be the case
that the memory and inhibitory demands of the task are handled differently across different stages of development (e.g., Albert &
Steinberg, 2011; Davidson et al., 2006). One compelling reason to explore the association between working memory and response
inhibition across age groups is to determine whether individuals with high working memory demonstrate mature response inhibition
at an earlier age than their low working memory counterparts.
In the present study, we explored the association between working memory capacity and response inhibition as a function of age.
In order to improve our ability to detect age differences in Stroop performance that may have been overlooked in previous cross-
sectional studies using this task, we explored Stroop performance across age and working memory in the context of task difficulty
(measured by block type). We predicted that higher working memory capacity would be associated with greater response inhibition
(i.e., a smaller Stroop effect), and that age differences in the Stroop effect would be comparatively smaller among individuals with
high working memory. Findings from this study contribute to the literature on cognitive development, which is currently limited in
its understanding of the interplay between working memory and inhibitory functioning across age.
2.1. Participants
Data were analyzed using a multinational sample of 5099 individuals ages 10 through 30 (M = 17.04 years; SD = 5.9). The
participants used for this study were initially recruited for an ongoing longitudinal study of parenting across cultures, Parent Behavior
and Child Adjustment Across Cultures (Lansford & Bornstein, 2011), which was approved by the participating university’s IRB (ap-
proval 2032), and has been described elsewhere (Steinberg et al., 2017). Participants were recruited from eleven countries: Guang-
Zhou and Shanghai, China (n = 484); Medellin, Colombia (n = 495); Nicosia, Cyprus (n = 344); Delhi, India (n = 416); Naples and
Rome, Italy (n = 543); Amman and Zarqa, Jordan (n = 418); Kisumu, Kenya (n = 463); Manila, the Philippines (n = 501); several
cities in the west of Sweden (n = 411); Chang Mai, Thailand (n = 495); and Durham and Winston-Salem, the United States (n = 529).
The gender distribution was nearly even within the full sample (49.3% (n = 2514) male) and within countries. Participants were
primarily working and middle class, with similar standings in terms of within-country socioeconomic status (SES). Participants in all
but the United States did not identify as being members of any ethnic minority groups. In the United States, approximately equal
numbers of Black, Latino, and White participants were enrolled.
2.2. Procedures
Participants were recruited via flyers posted in neighborhoods and schools, ads placed in newspapers, and word of mouth.
Because of the varied recruitment methods, we could not determine whether those who responded to recruitment ads differed from
those who did not. Informed consent was obtained from all adults age 18 and older, and parental consent and adolescent assent were
acquired for all individuals younger than 18. (In Sweden, informed consent was obtained from all participants age 15 and older, and
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parental consent and adolescent assent were acquired for all individuals younger than 15, in accordance with Swedish law.) Local
Institutional Review Boards approved all procedures.
Participants completed a 2-h test battery administered on laptop computers that included several behavioral tasks, self-report
measures, a demographic questionnaire, computerized tests of executive functions, and an intellectual functioning assessment. These
sessions were completed individually by the participant but in the presence of a research assistant in participants’ homes, schools, or
other locations designated by the participants.
To keep participants engaged, they were told that they would receive a base payment for participating, and that they could obtain
a bonus based on their performance on the computer tasks. In actuality, all participants received the bonus. This strategy was used to
increase motivation to perform well on tasks but ensure that no participants were penalized for their performance. In the United
States, the base payment was US$30 and the bonus was US$15. In other countries, the principal investigators and site coordinators
(with the approval of the local IRB) determined an appropriate amount of payment, accounting for the local standard of living and
minimum wage, and ensuring that the amount was sufficient to encourage participation but not so large so as to be coercive. (The
participating university in Sweden does not permit research subjects to be paid, so participants were given three movie tickets [two as
the base payment and one as a bonus] as compensation.)
Following each assessment, the interviewer answered five questions that asked about the participant’s perceived compliance and
engagement in the assessment and the quality of the data. A small number of assessments (3.2%, n = 172) were rated as unusable
(e.g., the participant did not appear to understand the questions or tasks, did not pay attention to instructions, or was obviously
disengaged); these cases were dropped from the analyses.
2.3. Measures
Measures were administered in the predominant language at each site, following forward- and back-translation and meetings to
resolve ambiguities in linguistic or semantic content (Erkut, 2010; Maxwell, 1996). Translators were fluent in English and the target
language. In addition to translating the measures, translators flagged items that did not translate well, were inappropriate for the
participants, were culturally insensitive, or elicited multiple meanings, and worked with site coordinators to make appropriate
modifications. Measures were administered in Mandarin Chinese (China), Spanish (Colombia and the United States), Italian (Italy),
Arabic (Jordan), Dholuo (Kenya), Filipino (the Philippines), Greek (Cyprus), Hindi (India), Swedish (Sweden), Thai (Thailand), and
American English (India, Kenya, the Philippines, and the United States).
2.3.1. Stroop
A computerized version of the classic Stroop color-word task was administered to assess prepotent response inhibition (see Banich
et al., 2007). On each trial, the participant was presented with either a color-word (e.g., “blue”, “yellow”) or a neutral, non-color
word (e.g., “Math”, “Add”) against a black screen and instructed to identify the color in which the word was printed (while ignoring
its semantic meaning) by pressing a corresponding key as quickly as possible. All color-word trials were incongruent such that the
color of the word did not match the semantic meaning of the word (e.g., the word “blue” displayed in yellow). There were no
congruent trials in this task.
Participants completed 16 practice trials followed by two 48-trial experimental blocks. Equal blocks included an equal mix of
neutral and incongruent trials (50/50) and unequal blocks included a greater number of neutral than incongruent trials (75/25). Half
of the participants were presented with an equal block first, and half of the participants were presented with an unequal block first.
Block order was assigned randomly and used as a covariate in all analyses. The order in which incongruent and neutral trials were
presented within these blocks was also random across participants.
The variable of interest was the Stroop effect, which was calculated as the difference in performance between incongruent and
neutral trials (i.e., Incongruent – Neutral) for both accuracy (percentage of correct responses) and response time (time recorded in
milliseconds) (Friedman & Miyake, 2004; Kane & Engle, 2003; Long & Prat, 2002; MacLeod, 1991; Schroeter et al., 2004; Veroude
et al., 2013). Only response times for accurate trials were used, consistent with previous research (e.g., Kane & Engle, 2003).
(Response times for inaccurate trials often yield excessive amounts of statistical noise that produce inaccurate and un-interpretable
representations of participant response patterns.) A larger Stroop effect is typically characterized by lower accuracy and longer
response times on incongruent relative to neutral trials. Thus, greater response inhibition was characterized by a smaller Stroop effect
for both accuracy and response time (e.g, MacLeod, 1991; Kane & Engle, 2003; Long & Prat, 2002).
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with a total of 64 trials (32 easy and 32 hard) that were presented in pseudo-random order, split into blocks of 8 trials each. Working
memory was measured as the number of correct responses on negative-recent trials (i.e., participants correctly indicated that the
current probe was not among the previous target set).
The spatial working memory task (Chein & Morrison, 2010) examined the ability to both maintain and retrieve information in
spatial working memory. Using a computer, subjects were shown a series of red squares on a white grid, presented one at a time (with
each square disappearing before the presentation of the subsequent square). After a short delay, participants were then asked to recall
the order in which the squares had appeared on the grid (by clicking with the computer mouse). This task was adaptive; when
subjects responded correctly, the task offered an additional square to remember (starting at a baseline of 3 squares for all partici-
pants). The number of test items increased until participants failed to correctly recall two successive trials at a given list length.
Spatial working memory was defined as the maximum list length for which all items were recalled in the correct serial order.
Finally, in the backwards digit span task (Wechsler, 1974), participants heard 12 sequences of digits (beginning with 2 digits and
increasing to 7) that they were asked to recall in the reverse order from which they had been presented. Backwards digit span was
defined as the highest number of digits correctly recalled backwards.
Items from all three tasks were standardized within the sample as a whole, and then averaged to create a working memory
composite score. Previous studies examining Stroop performance as a function of working memory capacity typically compare in-
dividuals at the bottom and top tertiles of the distribution (i.e., “low” and “high” working memory; Kane & Engle, 2003; Long & Prat,
2002). In the interest of preserving the continuous nature of the variable and using data from all participants rather than eliminating
a subset of the sample, working memory was used as a continuous variable in these analyses.
The purpose of the present study was to examine the relation between response inhibition and working memory across age.
Response inhibition (the Stroop effect) was computed as the difference in accuracy and response time between incongruent and
neutral trials (incongruent − neutral), across equal and unequal blocks. Two separate nonlinear mixed regression models were
conducted in Mplus Version 7.0—one for accuracy and one for response time. Block type (equal and unequal) was entered as a
dichotomous within-subjects variable. Age and working memory were continuous between-subjects variables. Age was centered on
10 years (the youngest age). A mixed modeling approach was used to account for the non-independence of the data within block type.
Both the linear and quadratic terms for age were tested to examine age patterns in response inhibition (the quadratic term was
included in light of previous work suggesting a curvilinear pattern of change in executive functioning across development).
In the first step of the analysis, the Stroop effect for accuracy was regressed on block type, age, and working memory. In the
second step, the quadratic term for age (age2) was added to the model. In the third step, the interaction between age and working
memory was examined (Age x WM), as well as the interaction between block type and age (Block x Age) and between block type and
working memory (Block x WM). In the fourth step, the two-way interaction between age2 and working memory was examined (Age2 x
WM), as well as the two-way interaction between age2 and block type (Age2 x Block), and the three-way interaction among block
type, age, and working memory (Block x Age x WM). Finally, the three-way interaction among block type, age2, and working memory
was examined (Block x Age2 x WM). This same analysis was repeated for the Stroop effect for response time.
Although culture was not a central component to the study, we chose to take advantage of our uniquely diverse sample and
explore age patterns in Stroop performance for accuracy and response time within individual countries. Based on previous research
suggesting noteworthy cross-cultural similarities in the development of self-regulation (Steinberg et al., 2017), we expected that age
would be associated with Stroop performance across cultures, with most countries evincing a linear increase in Stroop performance
across the adolescent years, followed by an apex in late adolescence or early adulthood. Using multiple group analysis, we entered
age in the first step of the analysis and age2 in the second step. The linear and quadratic effects of age were free to vary within
countries, but the covariates (described below) were constrained to be equal across countries. Constraining the covariates to be equal
across countries was necessary to avoid producing a saturated model, and is a method that has been used in previous cross-national
research (e.g., Duell et al., 2017; Steinberg et al., 2017).
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To control for practice effects, block order (i.e, whether participants started the task with unequal or equal blocks) was included as
a covariate in all analyses, as well as intellectual functioning, which has been consistently linked to executive functioning e.g.,
Unsworth, Fukuda, Awh, & Vogel, 2014). SES was also included as a covariate given findings demonstrating that across cultures,
socioeconomic factors such as parental education influence cognitive development (cf., Bradley & Corwyn, 2002). Country was also
included as a covariate in the primary analyses. Each country was entered as a dichotomous variable, with the United States excluded
as the comparison group. Correlations among the primary study variables and covariates are presented in Table 1. Gender was not
included as a covariate in the analysis given non-significant associations between gender and the main study variables. Results for
accuracy and response time are presented separately below.
3. Results
Adjusted means and standard errors for the Stroop effect across age, working memory group, and block type are presented in
Table 2 for accuracy and Table 3 for response time. Corresponding figures for the adjusted means are presented in Figs. 1 and 2 for
accuracy and response time, respectively. Adjusted means and standard errors for the individual countries included in our analyses
are tabled and graphed as a function of age in the supplementary material (for accuracy: Table and Fig. S1; for response time: Table
and Fig. S2).
3.1. Accuracy
Analysis of the Stroop effect for accuracy yielded a significant main effect of block type, such that individuals evinced a larger
Stroop effect for unequal than equal blocks. Furthermore, results yielded a significant effect of working memory, such that higher
working memory was associated with a lower Stroop effect for accuracy. Finally, there were significant linear and quadratic effects of
age (see Table 4 for regression coefficients). Fig. 3 illustrates the estimated regression coefficients for the linear and quadratic effects
of age on the Stroop effect for accuracy. Examination of the figure suggested that the Stroop effect for accuracy decreased linearly
across age groups before stabilizing in early adulthood and increasing again somewhat around the age of 30. There were no sig-
nificant interactions, indicating that block type, working memory, and age had independent effects on Stroop accuracy.
Table S3 in the supplementary material presents the within-country results for the linear and quadratic effects of age on the Stroop
effect for accuracy. Results indicate that most countries evinced a linear or quadratic function of age such that the Stroop effect for
accuracy decreased between the young adolescent and the adult age groups (age was not associated with Stroop performance in India
and Thailand). Age accounted for a small but comparable amount of variance (using R2) in the Stroop effect for accuracy across
countries. Examination of the graphed means in Fig. S1 suggests that in most countries, performance either plateaued in early
adulthood or continued improving into adulthood.
Results from the analysis examining the Stroop effect for response time revealed a main effect of block type, such that the Stroop
effect was larger in unequal than equal blocks. Results also pointed to a main effect of working memory, such that individuals with
higher working memory evinced a larger Stroop effect for response time (i.e., greater slowing on incongruent compared to neutral
trials). Furthermore, there were significant linear and quadratic effects of age groups, such that the Stroop effect increased linearly
through adolescence and stabilized in early adulthood. Finally, there was a three-way interaction among block type, working
memory, and the linear term for age. Given the presence of a significant quadratic effect of age, the three-way interaction suggested
that the instantaneous rate of change in the Stroop effect for response time (at age 10) varied as a function of working memory and
Table 1
Bivariate correlations among main study variables and covariates.
1 2 3 4 5 6 7 8 9
Note. RT = Response time; Acc = Accuracy. Values for RT and Accuracy reflect the Stroop effect (Incongruent – Neutral) within a given block (unequal/equal). For RT,
higher scores are associated with a larger Stroop effect; for accuracy, higher scores are associated with a lower Stroop effect. WM Comp = Working memory. Block
order is a dichotomous variable indicating whether participants played from equal (0) or unequal (1) blocks first.
* p < 0.05.
** p < 0.01.
*** p < 0.001.
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Table 2
Adjusted means (M) and standard errors (SE) for Stroop effect for accuracy for unequal and equal blocks within each age and working memory group.
Unequal Low −7.14 0.42 −6.49 0.65 −5.05 0.75 −6.19 0.85 −2.82 0.84 −5.30 0.86 −5.06 0.83 −5.44 0.31
Medium −8.04 0.54 −6.55 0.65 −3.33 0.71 −4.49 0.71 −4.59 0.72 −4.06 0.72 −4.70 0.71 −5.11 0.26
High −7.37 0.84 −5.39 0.83 −4.67 0.67 −2.53 0.66 −3.78 0.57 −3.10 0.61 −3.71 0.64 −4.37 0.28
Total −7.52 0.36 −6.15 0.41 −4.35 0.41 −4.41 0.43 −3.73 0.41 −4.15 0.42 −4.49 0.42 −4.97 0.15
Equal Low −6.08 0.34 −4.79 0.52 −5.14 0.61 −2.44 0.69 −3.92 0.68 −4.37 0.69 −2.97 0.67 −4.24 0.25
Medium −5.49 0.44 −4.28 0.53 −3.40 0.58 −3.57 0.57 −3.59 0.58 −3.10 0.58 −3.75 0.57 −3.88 0.21
High −6.55 0.68 −4.56 0.67 −3.25 0.54 −3.14 0.53 −2.10 0.46 −2.72 0.49 −3.03 0.52 −3.62 0.23
Total −6.04 0.29 −4.55 0.33 −3.93 0.33 −3.05 0.34 −3.20 0.33 −3.40 0.34 −3.25 0.34 −3.92 0.12
Note. Means and SEs adjusted for block order, intellectual functioning, SES, and country. Stroop effect for accuracy computed as: (% Incongruent Accuracy − %
Neutral Accuracy). Higher values indicate a lower Stroop effect. For purposes of presentation, working memory (WM) and age were categorized into groups. WM
groups were created based on WM scores at the lower (M = −0.83), middle (M = 0.06), and top (M = 0.8) tertiles of the distribution. In unequal blocks, the ratio of
neutral to incongruent trials was 3:1, respectively. In equal blocks, the ratio of neural to incongruent trials was 1:1. Italicized values represent grand means within each
age group (horizontal values) and within each working memory group (vertical values).
Table 3
Adjusted means (M) and standard errors (SE) for the Stroop effect for response time for unequal and equal blocks within each age and working memory group.
Unequal Low 37.83 3.06 39.64 4.70 42.84 5.47 43.59 6.17 57.97 6.09 48.34 6.25 59.65 6.02 47.12 2.28
Medium 46.98 3.92 42.90 4.73 43.54 5.19 60.59 5.17 71.54 5.21 59.57 5.22 62.67 5.15 55.40 1.88
High 47.16 6.11 34.27 6.04 49.49 4.89 52.84 4.76 64.14 4.12 56.87 4.42 59.47 4.68 52.03 2.05
Total 43.99 2.62 38.94 2.97 45.29 2.98 52.34 3.09 64.55 2.98 54.92 3.06 60.60 3.05 51.52 1.12
Equal Low 14.66 2.56 25.94 3.93 19.98 4.57 19.54 5.15 31.13 5.09 31.38 5.22 29.62 5.03 24.61 1.90
Medium 18.73 3.27 27.53 3.95 21.56 4.34 30.47 4.32 33.15 4.36 32.56 4.36 30.93 4.30 27.85 1.57
High 26.55 5.10 24.35 5.04 27.87 4.08 30.95 3.98 35.42 3.44 29.18 3.69 24.24 3.91 28.37 1.72
Total 19.98 2.19 25.94 2.48 23.14 2.49 26.99 2.58 33.23 2.49 31.04 2.56 28.26 2.55 26.94 0.93
Note. Means and SEs adjusted for block order, intellectual functioning, SES, and country. Stroop effect for response time computed as: (% Incongruent ms − % Neutral
ms). Higher values indicate a larger Stroop effect. For purposes of presentation, working memory (WM) and age were categorized into groups. WM groups were created
based on WM scores at the lower (M = −0.83), middle (M = 0.06), and top (M = 0.8) tertiles of the distribution. In unequal blocks, the ratio of neutral to incongruent
trials was 3:1, respectively. In equal blocks, the ratio of neural to incongruent trials was 1:1. Italicized values represent grand means within each age group (horizontal
values) and within each working memory group (vertical values).
Fig. 1. Adjusted means of the Stroop effect for accuracy across age for individuals with low, medium (MED), and high (HI) working memory within unequal (Un.) and
equal (Eq.) blocks. The Stroop effect was calculated as the difference in% accuracy between incongruent and neutral trials. The inverse of this value was graphed so
that higher values indicate a larger Stroop effect. Values represent means adjusted for block order, intellectual functioning, SES, and country. Working memory (WM)
and age were categorized into groups for purposes of presentation only. WM groups were created based on WM scores at the lower (M = −0.83), middle (M = 0.06),
and top (M = 0.8) tertiles of the distribution. In unequal blocks, the ratio of neutral to incongruent trials was 3:1, respectively. In equal blocks, the ratio of neural to
incongruent trials was 1:1. See Table 2 for corresponding mean values and standard errors.
block type, but that the overall shape of age patterns in the Stroop effect did not vary as a function of working memory and block type
(see Table 5 for the regression coefficients).
To probe the three-way interaction, we examined the two-way interaction between age and working memory in equal and
unequal blocks separately. As indicated in Table 6, there was no two-way interaction between age and working memory in unequal
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Fig. 2. Adjusted means of the Stroop effect for response time (RT) in milliseconds (ms) across age for individuals with low, medium (MED), and high (HI) working
memory within unequal (Un.) and equal (Eq.) blocks. The Stroop effect was calculated as the difference in response time between incongruent and neutral trials.
Values represent means adjusted for block order, intellectual functioning, SES, and country. Working memory (WM) and age were categorized into groups for purposes
of presentation only. WM groups were created based on WM scores at the lower (M = −0.83), middle (M = 0.06), and top (M = 0.8) tertiles of the distribution. In
unequal blocks, the ratio of neutral to incongruent trials was 3:1, respectively. In equal blocks, the ratio of neural to incongruent trials was 1:1. See Table 3 for
corresponding mean values and standard errors.
Table 4
Results from nonlinear multilevel model regression analysis for the Stroop effect for accuracy.
Note. Predictors were entered into the model in various steps (displayed under the Analysis heading). Random-mixed models indicate interactions between within- and
between-subjects variables. Mplus does not provide standardized estimates for models with random slopes. In the present analysis, the random slope of accuracy scores
regressed on block type was included as a moderating variable for the between-subjects variables of age and working memory (WM). For accuracy, higher scores are
indicative of a lower Stroop effect.
** p < 0.01.
*** p < 0.001.
Fig. 3. Age patterns in the Stroop effect for accuracy. The Stroop effect was calculated as the difference in % accuracy between incongruent and neutral trials. The
inverse of this value was graphed so that higher values indicate a larger Stroop effect. Values represent estimated regression coefficients.
blocks, but a significant two-way interaction in equal blocks. Further, age and working memory appeared to account for substantially
more variance in response time on equal blocks compared to unequal blocks. To further explore this effect, age patterns in the Stroop
effect for response time were graphed as a function of working memory by creating estimated slopes for individuals with low,
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N. Duell et al. Cognitive Development 47 (2018) 19–31
Table 5
Results from nonlinear multilevel model regression analysis for the Stroop effect for response time.
Note. Predictors were entered into the model in various steps (displayed under the Analysis heading). Random-mixed models indicate interactions between within- and
between-subjects variables. Mplus does not provide standardized estimates for models with random slopes. In the present analysis, the random slope of accuracy scores
regressed on block type was included as a moderating variable for the between-subjects variables of age and working memory (WM). For response time, higher scores
are indicative of a higher Stroop effect.
* p < 0.05.
** p < 0.01.
*** p < 0.001.
Table 6
Results from regression analyses examining the effect of age and working memory on the Stroop effect for response time in equal and unequal blocks separately.
Note. There was a significant 3-way interaction among block type, the linear term for age, and working memory. The present table displays results from two separate
regression analyses probing this interaction by examining the effect of age and working memory (WM) on the Stroop effefor response time in equal and unequal blocks
separately.
** p < 0.01.
*** p < 0.001.
Fig. 4. Age patterns in the Stroop efect for response time (RT) in milliseconds (ms) among individuals with low, medium, and high working memory (WM) in equal
blocks. The Stroop effect was calculated as the difference in RT between incongruent and neutral trials. WM groups were created for purposes of presentation only,
based on WM scores at the lower (M = −0.83), middle (M = 0.06), and top (M = 0.8) tertiles of the distribution. In equal blocks, the ratio of neutral to incongruent
trials was 1:1. Values represent estimated regression coefficients with a constant of 100 added, for ease of interpretation. Although there was no interaction with Age2,
this term was included in the model to more accurately depict the significant curvilinear trajectory of changes in RT across age.
medium, and high working memory (based on scores at the lower, middle, and top tertiles of the distribution; see Fig. 4). The figure
revealed a steep increase in the Stroop effect for response time between early adolescence and early adulthood among individuals
with low working memory. In contrast, among individuals with high working memory, there appeared to be little-to-no change in the
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N. Duell et al. Cognitive Development 47 (2018) 19–31
Stroop effect for response time between early adolescence and early adulthood, followed by a subtle decrease in the 20s.
Table S4 in the supplementary material presents results for the country-specific effects of age on the Stroop effect for response
time. As the table indicates, most countries in the sample evinced a linear or quadratic function of age (age was not associated with
Stroop performance in China and the US), suggesting that the Stroop effect for response time increased between the younger and
older age groups, such that late adolescents and adults slowed down responding in the presence of incongruent stimuli to a greater
extent than did younger adolescents. Consistent with the results for accuracy, age accounted for a minimal, but comparable amount
of variance (using R2) in Stroop performance across countries. Examination of the graphed means in Fig. S2 suggests that in most
countries, the Stroop effect either continued increasing into adulthood, or evinced a modest dip among the oldest adults.
4. Discussion
Evidence suggests that working memory facilitates response inhibition by supporting processes related to sustained attention and
goal maintenance (Engle, 2002), but few studies have explored this relation in a developmental context. In the present study, we
examined the association between working memory and response inhibition on the Stroop task across adolescence and early
adulthood. Traditionally, lower accuracy scores and slower response times on incongruent relative to neutral trials reflect a larger
Stroop effect and therefore weaker inhibitory control. The Stroop effect is thought to result from cognitive conflict induced by
incongruent trials, which is exacerbated by a deficient ability to resist interfering stimuli and a failure to maintain the task goal in
active memory. When measuring response inhibition in terms of accuracy, our results indicated that working memory was associated
with greater inhibitory control across development. On the other hand, when measuring response inhibition using response time, the
effect of age varied as a function of working memory, particularly in task conditions that minimized demands on working memory
(equal blocks). Thus, the effect of working memory on age differences in inhibitory control was most evident with respect to response-
time interference.
The Stroop effect for accuracy was generally lower among older individuals and individuals with high working memory. These
findings are in line with previous studies of differences in Stroop accuracy during adolescence and adulthood (Marsh et al., 2006) and
among individuals with low versus high working memory (Kane & Engle, 2003). Likewise, and consistent with work demonstrating
that response inhibition continues improving into early adulthood (Davidson et al., 2006; Luna et al., 2001), we found that inhibitory
control (measured using accuracy scores) followed a curvilinear trajectory across development, improving into the early 20s. Unlike
previous work demonstrating that age patterns in executive functioning vary as a function of task difficulty (Albert & Steinberg, 2011;
DeLuca et al., 2003; Huizinga et al., 2006; Luciana et al., 2005), we did not find that the age patterns observed in our study differed
between block types. Further, although we had hypothesized that individuals with high working memory would demonstrate mature
response inhibition at an earlier age than those with low working memory, we found no evidence that individual differences in
working memory moderated age differences in response inhibition—at least with respect to accuracy.
With respect to response time, age patterns in response inhibition varied as a function of both individual differences in working
memory and task difficulty. In unequal blocks, which placed higher demands on working memory by encouraging goal neglect, being
older was associated with a larger Stroop effect (i.e., more time spent on incongruent relative to neutral trials), independent of
individual differences in working memory. On the other hand, in equal blocks, which placed relatively fewer demands on working
memory, being older was associated with a larger Stroop effect only among individuals with relatively poorer working memory.
Among individuals with relatively higher working memory, age differences in the Stroop effect were comparatively subtler. This
moderating effect may have been driven by the 10 year olds in the low working memory group, who demonstrated a notably weaker
Stroop effect than older individuals in the low working memory group, and than all individuals in the high working memory group.
Alternatively, the finding that age was associated with a larger Stroop effect for response time among individuals with low working
memory may be reflective of these individuals slowing down their responding in order to preserve accuracy (Davidson et al., 2006;
Morey et al., 2012). This notion is in line with our finding that, regardless of individual differences in working memory, adults
demonstrated greater inhibitory control than young adolescents, evincing a lower Stroop effect for accuracy. Put differently, adults
with low working memory demonstrated greater response time interference compared to adults with higher working memory, despite
comparable accuracy scores.
Stroop interference is thought to be a function of two mechanisms: interference resolution on incongruent trials (i.e., resolving the
cognitive interference induced by color words being displayed in an incongruent font color) and goal maintenance (i.e., actively
maintaining in memory the need to indicate the color of the word rather than its meaning), which is especially difficult in unequal
blocks with infrequent incongruent trials. In studies of adults, the process of interference resolution is reflected primarily in response
times, and prevails in task contexts that minimize the need for goal maintenance, such as in equal blocks (Kane & Engle, 2003). Our
results have added to this finding by suggesting that the effect of working memory on age patterns in the Stroop effect for response
time are also limited to task contexts that minimize the need for goal maintenance. We do not have an obvious explanation as to why
age patterns in response inhibition varied as a function of working memory in equal but not unequal blocks. It may be that the effect
of working memory on response inhibition is primarily involved in interference resolution (which is a time-consuming process),
whereas other executive functions, such as attention (e.g., Unsworth, Redick, Lakey, & Young, 2010), are more prominently involved
in successful goal maintenance. Thus, individuals at a given age who vary in their working memory may be equally capable of
inhibiting prepotent responses, but those with low working memory take longer (compared to the time it takes to respond to neutral
trials) to resolve cognitive interference.
Differences between the correlates of inhibitory control indexed via accuracy versus response time are frequently reported in both
the developmental (see Andrews-Hanna et al., 2011; Huizinga et al., 2006; Marsh et al., 2006; Schroeter et al., 2004) and adult (Kane
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N. Duell et al. Cognitive Development 47 (2018) 19–31
& Engle, 2003; Long & Prat, 2002) literatures. For example, in a series of experiments comparing Stroop performance between young
adults with low and high working memory, Kane and Engle (2003) found that in task contexts with a high frequency of incongruent
trials (and therefore lower demands on working memory), working memory was related only to response time, but not accuracy. In
other words, individuals with low working memory took longer to respond to incongruent trials, but were still able to preserve their
accuracy. This is consistent with the present findings, which demonstrated that on equal blocks (with lower working memory de-
mands), individuals with low working memory took longer to respond to incongruent trials (compared to neutral trials) than did
individuals with high working memory. Differences in findings for response time and accuracy may be due to the extent to which age-
related differences in inhibitory functioning overlap with individual differences in working memory. Thus, age-related cognitive
development may determine the time it takes an individual to resolve cognitive conflict, regardless of accuracy, whereas individual
differences in working memory may affect the extent to which an individual is able to successfully inhibit prepotent responding (as
observed in the accuracy scores).
Results from the multiple group analyses examining age patterns in Stroop performance across countries yielded noteworthy
similarities, even when adjusting for in intellectual functioning and SES. In almost all countries, the Stroop effect for accuracy
decreased as a function of age, suggesting that across the world, inhibitory functioning (at least as measured by accuracy) improves
across adolescence and into adulthood, consistent with findings from previous cross-cultural research (Steinberg et al., 2017). Results
for response time indicated that in almost all countries, the Stroop effect increased as a function of age, consistent with the results of
the full-sample analysis, and suggesting that older individuals may slow down responding in the presence of incongruent stimuli in an
effort to preserve accuracy. We do not have an obvious explanation as to why we did not observe an association between age and
Stroop performance among a small number of countries (India and Thailand for accuracy; China and the US for response time),
although observation of the means suggests that floor effects (in India, Thailand, and the US) and ceiling effects (in China) may have
precluded improvement with age.
The extent of the observed cross-national similarities in inhibitory control may be a function of patterns in neurological devel-
opment in prefrontal brain regions subserving executive functions, a developmental process that is thought to be nearly universal
(e.g., Spear, 2013). Granted, age only accounted for a small portion of the variance in inhibitory control within countries; thus, there
are surely various other, potentially country-specific, factors influencing age patterns in inhibitory control. For example, countries
around the world vary in the expectations for and socialization practices of self-regulation (Larson, Wilson, & Rickman, 2009). Many
non-Western countries such as China, for example, place a strong emphasis on self-control and discipline (Chaudhary & Sharma,
2012; Chen, Cen, Li, & He, 2005). For this reason, individuals from non-Western countries may evince adult-like inhibitory control at
an earlier age, or they may evince greater inhibitory control overall compared to people from countries that do not place such a
strong emphasis on self-control (e.g., Rubin et al., 2006). Ultimately, more nuanced examinations of factors contributing to country-
level differences in cognitive development will be important for future research. At the most basic level, it seems that age patterns in
inhibitory control are largely consistent across cultures, but that the level of inhibitory functioning and the age at which this
functioning reaches adult levels is likely influenced by various cultural factors.
Although these are novel findings, there are a few limitations of this study that warrant caution when interpreting the results.
While other studies examining working memory differences in Stroop performance have tended to use complex working memory
span tasks having both a storage and a processing component (e.g., operation or reading span task) to index working memory
capacity (e.g., Hutchison, 2011; Kane & Engle, 2003; Long & Prat, 2002), ours utilized a composite of storage-only working memory
measures (item recognition, spatial span, and backwards digit span). Complex span tasks may tax domain-general aspects of working
memory to a greater extent than the tasks included in our battery. Although previous work has considered item recognition, spatial
span, and backwards digit span tasks as valid measures of working memory (e.g., Oberauer, Süß, Schulze, Wilhelm, & Wittmann,
2000; Thompson-Schill et al., 2002), it is possible that these tasks are best suited to capture variance with respect to storage in “short-
term memory” rather than the executive processes most often described as working memory (Conway et al., 2005). We note,
however, that because of the use of a composite index, we can be more confident that the observed differences in Stroop performance
were not dependent upon idiosyncratic features of a specific task. Future developmental studies of response inhibition and working
memory could benefit from an extension of these findings using different measures of working memory capacity and perhaps a
construct-level assessment of response inhibition.
An additional limitation of our study is that the Stroop task did not include congruent trials (i.e., trials in which the color of the
word matches its meaning), which may have affected our findings on age and working memory differences in response inhibition
(e.g., Andrews-Hanna et al., 2011; Hutchison, 2011; Kane & Engle, 2003). In addition to presenting non-conflicting stimuli, congruent
trials encourage word-reading, which ultimately becomes an adaptive (time-saving) strategy in blocks with a high proportion of
congruent trials. From this vantage point, congruent trials increase the potential for interference on incongruent trials, when word
reading is no longer an adaptive strategy. Thus, it is possible that including blocks that intermix congruent and incongruent trials
(rather than neutral and incongruent as was done in our study), may increase the overall difficulty of the task, potentially yielding
different results with respect to working memory differences in Stroop performance across age. Relatedly, the block manipulations
(i.e., equal and unequal) in our Stroop task did not appear to have a strong effect on participant performance, thus limiting our ability
to draw conclusions about the extent to which task difficulty interferes with inhibitory control across age and in relation to individual
differences in working memory. Future studies may benefit from more extreme variations of block manipulation, such as blocks with
0% and 75% congruent trials (rather than 50% and 75% as was used in our study) (see Kane & Engle, 2003).
One final consideration is our use of cross-sectional rather than longitudinal data. Although the cross-sectional design employed
in the present study did not allow for any conclusions to be made regarding the development of inhibitory functioning, it was well-
suited for the aims of the study, which focused on determining whether the associations between working memory and inhibitory
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functioning observed in previous studies of young adults were also present across different stages of development. Using a cross-
sectional design affords an examination of age differences (e.g., adolescence versus adulthood) in the association between working
memory and inhibitory control. Future research interested in examining predictors and moderators of the developmental trajectory of
inhibitory control as a function of working memory would benefit from a longitudinal design. Notwithstanding the importance of
longitudinal investigations of cognitive development, the research aims of the present study were ultimately more adequately ad-
dressed using a cross-sectional design.
5. Conclusions
The present study is one of the first to explore the association between working memory and response inhibition in a cross-
sectional sample. The findings from this study contribute to the developmental literature on Stroop performance, which currently
lacks an integrative account of how the interaction between development and individual differences influence executive functioning.
By accounting for these factors in our study, in addition to including a large sample that covers a wide span of development, we were
able to demonstrate that (a) working memory is associated with behavioral manifestations of inhibitory control, largely independent
of age; (b) older age and higher working memory capacity are associated with greater inhibitory control when measured using
accuracy; and (c) age differences in inhibitory control (as indexed by response time) are most pronounced among individuals with
low working memory. Such findings may be relevant to research on working memory training, which has already offered preliminary
evidence of transfer onto other executive functions such as response inhibition (see Chein & Morrison, 2010; Flook et al., 2010;
Karback & Kray, 2009; Klingberg, Forssberg, & Westerberg, 2002; Olesen, Westerberg, & Klingberg, 2004). Further, considering the
importance of inhibitory functioning during the adolescent years, specifically with respect to academic achievement, occupational
success, law-abiding behaviors, and psychological well-being (Moffitt et al., 2013), understanding the ways in which inhibitory
control may be improved during this developmental period has important implications for adolescent development and well-being. A
compelling next step for future research might be to explore how individual differences in executive functioning influence a variety of
outcomes in adolescence, such as academic achievement and risk taking.
Conflicts of interest
None.
Supplementary data associated with this article can be found, in the online version, at https://doi.org/10.1016/j.cogdev.2018.02.
003.
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