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Assignment Unit - 7, Genetics and Evolution

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XII BIOLOGY ASSIGNMENT GENETICS AND EVOLUTION

PRINCIPLES OF INHERITANCE AND VARIATION

1) What is Down’s syndrome? Give its symptoms and cause. Why is it that the chances of having a
child with Down’s syndrome increases if the age of the mother exceeds forty years? 3
2) (i) Why are grasshopper and Drosophila said to show male heterogamety? Explain.
(ii) Explain female heterogamety with the help of an example. 3
3) (a) How does mutation occur? 3
(b) Differentiate between point mutation and frameshift mutation
4) A red-eyed heterozygous female fruit fly is crossed with a red-eyed male. Work out all possible
genotypes and phenotypes of the progeny. Comment on the pattern of inheritance of eye colour
in fruit flies. 2
5) Explain the phenomena of dominance, multiple allelism and co-dominance taking ABO blood
group as an example. 2
6) In snapdragon (Antirrhinum majus), a plant with red flowers was crossed with a plant with
white flowers. Work out all the possible genotypes and phenotypes of F1 and F2 generations.
Comment on the pattern of inheritance in this case 2
7) Linkage and crossing-over of genes are alternatives of each other. Justify with the help of an
example. 2
8) Write the symptoms of haemophilia and sickle-cell anaemia in humans. Explain how the
inheritance pattern of the two diseases differs from each other. 2

Molecular Basis of Inheritance


1) Briefly describe the following:
(a) Transcription (b) Polymorphism (c) Translation (d) Bioinformatics
2) Draw a schematic diagram of lac operon
(i) In the absence of inducer (ii) In the presence of inducer
3) Draw a labelled schematic sketch of replication fork of DNA. Explain the role of the DNA
polymerase and Deoxyribonuclioside triphosphates .
4) Draw a labelled schematic structure of a transcription unit. Explain the function of each
component in the unit in the process of transcription.
5) One of the codons on mRNA is AUG. Draw the structure of tRNA adapter molecule for this codon.
Explain the uniqueness of this tRNA.
6) Explain how the biochemical characterisation (nature) of ‘Transforming Principle’ was
determined, which was not defined from Griffith’s experiments.
7) Explain the significance of satellite DNA and VNTR in DNA fingerprinting technique
8) Write salient features of the human genome as drawn from the human genome project.

Evolution
1) How does industrial melanism support Darwin’s theory of Natural Selection? Explain.
2) What is disturbance in Hardy-Weinberg genetic equilibrium indicative of? Explain how it is caused.
3) What was proposed by Oparin and Haldane on origin of life? How did S.L. Miller’s experiment
support their proposal?
4) Differentiate between analogy and homology giving one example each of plant and animal
respectively.
5) Explain the fallowing term (a) adaptive radiation (b) convergent evolution (c) founder effect
6) If 70% recessive alleles of a character present in population find (a) frequency of dominant
individuals (b) frequency of hetrozygous individuals

PREPARED BY –SUDHEER VERMA (ACADEMIC CO-ORDINATOR)


LUCKNOW PUBLIC SCHOOL [A C.P. SINGH FOUNDATION] Page 1

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